Results 141 to 150 of about 436,421 (289)

Mechanism of action and potential therapeutic targets of TGF-β-related signaling pathway and its downstream miRNA expression in pulmonary arterial hypertension

Frontiers in Pharmacology
Pulmonary hypertension is a major cardiovascular disease characterized by the persistent elevation of pulmonary artery pressure, leading to vascular remodeling, fibrosis, and endothelial dysfunction.
Yimo Huang, Wende Ma, Cen Guo, Cen Guo, Xiaoling Su   +4 more
doaj   +1 more source

4D Bioprinted Self‐Folding Scaffolds Enhance Cartilage Formation in the Engineering of Trachea

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
A bilayer self‐folding scaffold, triggerable by humidity, is fabricated via 4D bioprinting for trachea engineering. An analytical model is derived to predict its radius of curvature, enabling its scalability. Cartilage progenitor cells seeded on the scaffold perceive scaffold final curvature and react to it, by enhancing the upregulation of pro ...
Irene Chiesa, Alessio Esposito, Giovanni Vozzi, Riccardo Gottardi, Carmelo De Maria   +4 more
wiley   +1 more source

Extract of Aquilaria crassna leaves and mangiferin are vasodilators while showing no cytotoxicity

Journal of Traditional and Complementary Medicine, 2019
The leaves of Aquilaria spp. promote “physiological balance”, and are “cardiotonic and provide blood nourishment”. In Asia, these leaves are increasingly consumed as tea and claimed to provide benefits to cardiovascular function, albeit without any ...
Sutthinee Wisutthathum, Natakorn Kamkaew, Anjaree Inchan, Usana Chatturong, Tamkeen Urooj Paracha, Kornkanok Ingkaninan, Eakkaluk Wongwad, Krongkarn Chootip   +7 more
doaj  

Local regulation of the coronary circulation in health and disease: role of nitric oxide and endothelin [PDF]

, 2016
Coronary artery disease is the leading cause of morbidity and mortality in western countries. Its pathogenesis is unknown, but involves enhanced vasoconstriction, increased interaction of platelets and monocytes with the vessel wall, as well as ...
Lüscher, T. F., Noll, G., Wenzel, R. R.
core  

Miniaturized Devices for On‐the‐Spot Generation of Small‐Diameter Vascular Grafts

Advanced Materials Technologies, EarlyView.
An intracorporeal extrusion device is developed for on‐the‐spot generation of vascular grafts with tunable diameters spanning from 1 to 6 mm. The device uses biomimetic polymers and light, to promptly obtaining biocompatible and high‐burst pressure‐resistant grafts.
Deyanira Hernandez‐Sanchez, Maxime‐Emmanuel Comtois‐Bona, Antony El‐Khoury, Sergio David Garcia Schejtman, Aidan Macadam, Juan‐David Figueroa‐Alegria, Jesus M. Calderon‐Torres, Irene Guzmán‐Soto, Marc Ruel, Erik J. Suuronen, Marcelo Muñoz, Emilio I. Alarcon   +11 more
wiley   +1 more source

Paxillin participates in the sphingosylphosphorylcholine-induced abnormal contraction of vascular smooth muscle by regulating Rho-kinase activation

Cell Communication and Signaling
Background The Ca2+-independent contraction of vascular smooth muscle is a leading cause of cardiovascular and cerebrovascular spasms. In the previous study, we demonstrated the involvement of Src family protein tyrosine kinase Fyn and Rho-kinase in the ...
Ying Zhang, Nan Li, Sei Kobayashi
doaj   +1 more source

Microfluidic Platform with Local Oxygen Sensors Demonstrates That 3D Blood Vessel Networks Exhibit Time‐Dependent Changes in Oxygen Concentrations During Their Formation and Perfusion

Advanced Materials Technologies, EarlyView.
Novel OoC platform with functional vascular networks highlights challenges in oxygenation. This study uses optical oxygen sensors to monitor oxygen during vascular formation, revealing perfusion limitations and highlighting the need for better oxygenation strategies.
Tarek Gensheimer, Stefanie Fuchs, Laura E. de Heus, Kim Vermeul, Torsten Mayr, Andries v.d. Meer   +5 more
wiley   +1 more source

Transformative 4D Printed SMPs into Soft Electronics and Adaptive Structures: Innovations and Practical Insights

Advanced Materials Technologies, EarlyView.
This review highlights recent advancements in 3DP techniques that incorporate emerging multifunctional SMP materials for applications in e‐electronics, soft actuators, biomedical devices, and more. Abstract Shape memory polymers (SMP) have recently gained significant attention as multifunctional materials for flexible and wearable electronics ...
Muhammad Yasir Khalid, Adam Otabil, Omar Samir Mamoun, Khalid Askar, Mahdi Bodaghi   +4 more
wiley   +1 more source

Adaptive Elastin‐Like Hydrogel with Unidirectional and Controllable Anisotropic Actuation for Soft Robotics and Tissue Engineering

Advanced Materials Technologies, EarlyView.
Fiber‐reinforced elastin‐like tubular scaffolds are engineered to achieve anisotropic and reversible actuation under external stimuli. By adjusting fiber's angle, actuation behavior is finely tuned, enabling distinct actuation responses, even within different regions of the same scaffold.
Federica Sallustio, Amanda Schmidt, Ikram El Maachi, Alexander Greenhalgh, Martin Frydrych, Stefan Jockenhoevel, José Carlos Rodríguez‐Cabello, Alicia Fernández‐Colino   +7 more
wiley   +1 more source

Recent Advances in Variable‐Stiffness Robotic Systems Enabled by Phase‐Change Materials

Advanced Robotics Research, EarlyView.
Phase‐change materials (PCMs), such as shape memory alloys, hydrogels, shape memory polymers, liquid crystal elastomers, and low‐melting‐point alloys, are driving advancements in stiffness‐tunable robotic systems across a wide range of applications. This review highlights recent progress in PCM‐enabled robotics, focusing on their underlying mechanisms,
Sukrit Gaira, Liao Wu, Ming Li, Priyank Kumar, Xiaopeng Li, Shi‐Yang Tang   +5 more
wiley   +1 more source