Results 211 to 220 of about 162,609 (263)
Some of the next articles are maybe not open access.
2018
Muscle atrophy typically is a direct effect of protein degradation induced by a diversity of pathophysiologic states such as disuse, immobilization, denervation, aging, sepsis, cachexia, glucocorticoid treatment, hereditary muscular disorders, cancer, diabetes and obesity, kidney and heart failure, and others.
Adrian, Dumitru +3 more
openaire +2 more sources
Muscle atrophy typically is a direct effect of protein degradation induced by a diversity of pathophysiologic states such as disuse, immobilization, denervation, aging, sepsis, cachexia, glucocorticoid treatment, hereditary muscular disorders, cancer, diabetes and obesity, kidney and heart failure, and others.
Adrian, Dumitru +3 more
openaire +2 more sources
Mechanisms of skeletal muscle atrophy
Current Opinion in Rheumatology, 2006Recent clinical and mechanistic studies have shown that increased proteolysis is a major determinant of muscle wasting in numerous catabolic states and of alterations in myopathies or dystrophies. The implications of these observations for improving muscle mass and function are discussed.Several proteolytic systems (i.e. the ubiquitin-proteasome system,
Ventadour, Sophie, Attaix, Didier
openaire +3 more sources
Imaging Patterns of Muscle Atrophy
Seminars in Musculoskeletal Radiology, 2018AbstractThe role of muscle imaging in the diagnosis of inherited and acquired muscle diseases has gained clinical relevance. In particular, magnetic resonance imaging (MRI) is increasingly being used for diagnostic purposes, especially with its capability of whole-body musculature assessment.
Marc-André, Weber +2 more
openaire +2 more sources
Glucocorticoid-induced skeletal muscle atrophy
The International Journal of Biochemistry & Cell Biology, 2013Many pathological states characterized by muscle atrophy (e.g., sepsis, cachexia, starvation, metabolic acidosis and severe insulinopenia) are associated with an increase in circulating glucocorticoids (GC) levels, suggesting that GC could trigger the muscle atrophy observed in these conditions. GC-induced muscle atrophy is characterized by fast-twitch,
O, Schakman +4 more
openaire +2 more sources
Science Signaling, 2010
Denervation makes muscles more responsive to the muscle-wasting cytokine TWEAK.
openaire +1 more source
Denervation makes muscles more responsive to the muscle-wasting cytokine TWEAK.
openaire +1 more source
2018
Muscle is the most abundant tissue in human body, and it can be atrophy when synthesis is inferior to degradation. Muscle atrophy is prevalent as it is a complication of many diseases. Besides its devastating effects on health, it also decreases life quality and increases mortality as well.
Shengguang, Ding +4 more
openaire +2 more sources
Muscle is the most abundant tissue in human body, and it can be atrophy when synthesis is inferior to degradation. Muscle atrophy is prevalent as it is a complication of many diseases. Besides its devastating effects on health, it also decreases life quality and increases mortality as well.
Shengguang, Ding +4 more
openaire +2 more sources
Physical Exercise for Muscle Atrophy
2018The most direct characteristic of muscle atrophy is reduction in muscle mass, which is due to increased protein degradation or reduced protein synthesis in skeletal muscle. The loss of muscle mass can directly affect the quality of daily life, prolong the recovery period, and become the main risk factor for chronic diseases. However, there is currently
Liang, Shen +3 more
openaire +2 more sources
Noncoding RNAs in Muscle Atrophy
2018Denervation, disuse, fasting, and various diseases could induce skeletal muscle atrophy, which results in the decline of life quality and increase of the mortality risk for patients. Noncoding RNAs (ncRNAs) are implicated important in regulating gene expression.
Yongqin, Li +4 more
openaire +2 more sources
Muscle Atrophy: Present and Future
2018Muscle atrophy is the loss of muscle mass and strength, and it occurs in many diseases, such as cancer, AIDS (acquired immunodeficiency syndrome), congestive heart failure, COPD (chronic obstructive pulmonary disease), renal failure, and severe burns.
Richard Y, Cao +4 more
openaire +2 more sources
Archives of Neurology, 1970
DENERVATION of striated muscle leads to characteristic histological, histochemical, physiological, and pharmacological changes which have been ascribed to the loss of a trophic influence of nerve on muscle. The exact nature of this trophic effect has not been determined, although the release of acetylcholine at the motor end-plate seems necessary to ...
openaire +2 more sources
DENERVATION of striated muscle leads to characteristic histological, histochemical, physiological, and pharmacological changes which have been ascribed to the loss of a trophic influence of nerve on muscle. The exact nature of this trophic effect has not been determined, although the release of acetylcholine at the motor end-plate seems necessary to ...
openaire +2 more sources