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Miro1-mediated mitochondrial transfer boosts stem cell therapy for muscle atrophy via restoring mitochondrial homeostasis. [PDF]
Stem Cell Res TherZhao F +10 more
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Estrogen deficiency induces pelvic floor muscle atrophy via ERα/GLUT4 pathway. [PDF]
PLoS OneHuang X +11 more
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Current Progress in the Role of Ferroptosis in Skeletal Muscle Atrophy. [PDF]
Mediators InflammChen Y +5 more
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Inactivation of SERCA2 at Cys674 induces skeletal muscle atrophy by activating the TGFβ/Smad-S100a4 axis to promote inflammation. [PDF]
Redox BiolNan F +10 more
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Muscle Atrophy and the Sestrins
New England Journal of Medicine, 2020Sussing out the Sestrins Two recent scientific reports implicate the sestrin proteins in protecting against muscle atrophy, which occurs in old age and with disuse, denervation, and systemic inflam...
J.A. Jeevendra Martyn, Masao Kaneki
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2020
The incidence of muscle atrophy is increasing with each passing year, which imposes a huge burden on the quality of life of patients. It is a public health issue that causes a growing concern around the world. Exercise is one of the key strategies to prevent and treat various diseases.
Nana, He, Honghua, Ye
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The incidence of muscle atrophy is increasing with each passing year, which imposes a huge burden on the quality of life of patients. It is a public health issue that causes a growing concern around the world. Exercise is one of the key strategies to prevent and treat various diseases.
Nana, He, Honghua, Ye
openaire +2 more sources
Neuromuscular Disorders, 1993
Two patients with slowly progressive muscle atrophy limited to only one leg are reported. They had pes equinovarus deformity and muscle weakness in the affected leg but no symptom in the other limbs. Muscle biopsies from the affected leg showed dystrophic changes consisting of variation in muscle fiber size, endomysial fibrosis, and necrotic and ...
M, Takemitsu +6 more
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Two patients with slowly progressive muscle atrophy limited to only one leg are reported. They had pes equinovarus deformity and muscle weakness in the affected leg but no symptom in the other limbs. Muscle biopsies from the affected leg showed dystrophic changes consisting of variation in muscle fiber size, endomysial fibrosis, and necrotic and ...
M, Takemitsu +6 more
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2018
The endocrine system is an essential regulator of muscle metabolism in both health and disease. Hormones such as growth hormone (GH), insulin-like growth factor-I (IGF-I) and androgens are the main regulators of muscle metabolism in both health and disease; have profound influences on muscle, acting as anabolic factors; and are important regulators of ...
Ana Isabel, Martín +2 more
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The endocrine system is an essential regulator of muscle metabolism in both health and disease. Hormones such as growth hormone (GH), insulin-like growth factor-I (IGF-I) and androgens are the main regulators of muscle metabolism in both health and disease; have profound influences on muscle, acting as anabolic factors; and are important regulators of ...
Ana Isabel, Martín +2 more
openaire +2 more sources
Science Signaling, 2001
Muscle atrophy that occurs when physical activity is decreased results from enhanced breakdown of muscle protein by the ubiquitin proteasome pathway, but the precise molecular mediators are unknown. Using gene expression profiling methods and subsequent analyses of knockout mice, Bodine et al.
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Muscle atrophy that occurs when physical activity is decreased results from enhanced breakdown of muscle protein by the ubiquitin proteasome pathway, but the precise molecular mediators are unknown. Using gene expression profiling methods and subsequent analyses of knockout mice, Bodine et al.
+4 more sources
2018
Muscle is the most abundant tissue in human body, and it can be atrophy when synthesis is inferior to degradation. Muscle atrophy is prevalent as it is a complication of many diseases. Besides its devastating effects on health, it also decreases life quality and increases mortality as well.
Shengguang, Ding +4 more
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Muscle is the most abundant tissue in human body, and it can be atrophy when synthesis is inferior to degradation. Muscle atrophy is prevalent as it is a complication of many diseases. Besides its devastating effects on health, it also decreases life quality and increases mortality as well.
Shengguang, Ding +4 more
openaire +2 more sources