Results 1 to 10 of about 467,254 (265)

Extracellular vesicle distribution and localization in skeletal muscle at rest and following disuse atrophy

Skeletal Muscle, 2023
Background Skeletal muscle (SkM) is a large, secretory organ that produces and releases myokines that can have autocrine, paracrine, and endocrine effects.
Ahmed Ismaeel, Douglas W. Van Pelt, Zachary R. Hettinger, Xu Fu, Christopher I. Richards, Timothy A. Butterfield, Jonathan J. Petrocelli, Ivan J. Vechetti, Amy L. Confides, Micah J. Drummond, Esther E. Dupont-Versteegden   +10 more
doaj   +1 more source

Muscle-Specific Cellular and Molecular Adaptations to Late-Life Voluntary Concurrent Exercise

Function, 2022
Murine exercise models can provide information on factors that influence muscle adaptability with aging, but few translatable solutions exist. Progressive weighted wheel running (PoWeR) is a simple, voluntary, low-cost, high-volume endurance/resistance ...
Cory M Dungan, Camille R Brightwell, Yuan Wen, Christopher J Zdunek, Christine M Latham, Nicholas T Thomas, Alyaa M Zagzoog, Benjamin D Brightwell, Georgia L Nolt, Alexander R Keeble, Stanley J Watowich, Kevin A Murach, Christopher S Fry   +12 more
doaj   +1 more source

The Effect of Bacterial Endotoxin LPS on Serotonergic Modulation of Glutamatergic Synaptic Transmission

Biology, 2020
The release of the endotoxin lipopolysaccharides (LPS) from gram-negative bacteria is key in the induction of the downstream cytokine release from cells targeting cells throughout the body.
Jate Bernard, Abigail Greenhalgh, Oscar Istas, Nicole T. Marguerite, Robin L. Cooper   +4 more
doaj   +1 more source

Prior AICAR induces elevated glucose uptake concomitant with greater γ3-AMPK activation and reduced membrane cholesterol in skeletal muscle from 26-month-old rats

FACETS, 2022
Attenuated skeletal muscle glucose uptake (GU) has been observed with advancing age. It is important to elucidate the mechanisms linked to interventions that oppose this detrimental outcome. Earlier research using young rodents and (or) cultured myocytes
Haiyan Wang, Amy Zheng, Edward B. Arias, Gregory D. Cartee   +3 more
doaj   +1 more source

Fusion-Independent Satellite Cell Communication to Muscle Fibers During Load-Induced Hypertrophy

Function, 2020
The “canonical” function of Pax7+ muscle stem cells (satellite cells) during hypertrophic growth of adult muscle fibers is myonuclear donation via fusion to support increased transcriptional output.
Kevin A Murach, Ivan J Vechetti, Douglas W Van Pelt, Samuel E Crow, Cory M Dungan, Vandre C Figueiredo, Kate Kosmac, Xu Fu, Christopher I Richards, Christopher S Fry, John J McCarthy, Charlotte A Peterson   +11 more
doaj   +1 more source

In Vitro Fish Models for the Analysis of Ecotoxins and Temperature Increase in the Context of Global Warming

Toxics, 2021
Rising temperatures can affect fish survival, especially from shallower waters, as temperatures increase faster and more intensively in these areas; thus, species-specific temperature tolerance can be exceeded.
Bianka Grunow, George Philipp Franz, Katrin Tönißen   +2 more
doaj   +1 more source

Role of steroid growth promoter on growth performance and meat quality traits in broiler

Poultry Science, 2022
: Growth promoters are added with broiler feed to boost the overall feed efficiency and growth rate. The current study investigated the effect of dexamethasone (DEX)—a commonly used growth promoter—on the broiler growth rate, meat quality, and muscle ...
Rafiqul Islam, Nasrin Sultana, Ummay Ayman, Mohammad Rafiqul Islam, Md. Abul Hashem   +4 more
doaj   +1 more source

Transcriptional Time Course After Rotator Cuff Tear

Frontiers in Physiology, 2021
Rotator cuff (RC) tears are prevalent in the population above the age of 60. The disease progression leads to muscle atrophy, fibrosis, and fatty infiltration in the chronic state, which is not improved with intervention or surgical repair.
Laura S. Vasquez-Bolanos, Laura S. Vasquez-Bolanos, Michael C. Gibbons, Michael C. Gibbons, Severin Ruoss, Isabella T. Wu, Mario Vargas-Vila, Sydnee A. Hyman, Sydnee A. Hyman, Mary C. Esparza, Donald C. Fithian, John G. Lane, Anshuman Singh, Anshuman Singh, Chanond A. Nasamran, Kathleen M. Fisch, Samuel R. Ward, Samuel R. Ward, Samuel R. Ward   +18 more
doaj   +1 more source

A novel tetracycline-responsive transgenic mouse strain for skeletal muscle-specific gene expression

Skeletal Muscle, 2018
Background The tetracycline-responsive system (Tet-ON/OFF) has proven to be a valuable tool for manipulating gene expression in an inducible, temporal, and tissue-specific manner.
Masahiro Iwata, Davis A. Englund, Yuan Wen, Cory M. Dungan, Kevin A. Murach, Ivan J. Vechetti, Christopher B. Mobley, Charlotte A. Peterson, John J. McCarthy   +8 more
doaj   +1 more source

Transcriptional time course after rotator cuff repair in 6 month old female rabbits

Frontiers in Physiology, 2023
Introduction: Rotator cuff tears are prevalent in the population above the age of 60. The disease progression leads to muscle atrophy, fibrosis, and fatty infiltration, which is not improved upon with surgical repair, highlighting the need to better ...
Laura S. Vasquez-Bolanos, Laura S. Vasquez-Bolanos, Michael C. Gibbons, Michael C. Gibbons, Severin Ruoss, Isabella T. Wu, Mary C. Esparza, Donald C. Fithian, John G. Lane, Anshuman Singh, Anshuman Singh, Chanond A. Nasamran, Kathleen M. Fisch, Kathleen M. Fisch, Samuel R. Ward, Samuel R. Ward, Samuel R. Ward   +16 more
doaj   +1 more source