Results 11 to 20 of about 467,254 (265)

Role of autophagy in bone and muscle biology. [PDF]

open access: yesWorld J Stem Cells, 2016
Autophagy in eukaryotic cells is a constitutive process and functions as a homeostatic mechanism; it is upregulated in response to specific stress stimuli such as starvation, hypoxia and as oxidative stress. In addition to playing a crucial role in adaptive responses to different stimuli, autophagy is also required for intracellular quality control ...
Valenti MT, Dalle Carbonare L, Mottes M.
europepmc   +3 more sources

Emerging role of HDAC11 in skeletal muscle biology. [PDF]

open access: yesFront Cell Dev Biol
HDAC11 is an epigenetic repressor of gene transcription, acting through its deacetylase activity to remove functional acetyl groups from the lysine residues of histones at genomic loci. It has been implicated in the regulation of different immune responses, metabolic activities, as well as cell cycle progression. Recent studies have also shed lights on
Chen J, Li Q.
europepmc   +4 more sources

Antioxidants Reduce Muscular Dystrophy in the dy2J/dy2J Mouse Model of Laminin α2 Chain-Deficient Muscular Dystrophy

open access: yesAntioxidants, 2020
Congenital muscular dystrophy with laminin α2 chain-deficiency (LAMA2-CMD) is a severe neuromuscular disorder without a cure. Using transcriptome and proteome profiling as well as functional assays, we previously demonstrated significant metabolic ...
Vahid M. Harandi   +5 more
doaj   +1 more source

Molecular biology of muscle development [PDF]

open access: yesCell, 1994
Margaret Buckingham Department of Molecular Biology Pasteur Institute 25, rue du Dr. Roux 75724 Paris Cedex 15 France In April 1994 a Keystone Symposium on the Molecular Biology of Muscle Development, organized by E. Band- man (University of California, Davis, Davis, California), E. Olson (M. D. Anderson Cancer Center, Houston), and N.
openaire   +3 more sources

Myopathy of the upper airway in snoring and obstructive sleep apnea

open access: yesLaryngoscope Investigative Otolaryngology, 2022
Objective Previous reports of muscle changes in the upper airways of obstructive sleep apnea (OSA) patients have primarily been attributed to acquired nerve lesions due to snoring vibrations.
Farhan Shah, Per Stål
doaj   +1 more source

Differences in muscle satellite cell dynamics during muscle hypertrophy and regeneration

open access: yesSkeletal Muscle, 2022
Skeletal muscle homeostasis and function are ensured by orchestrated cellular interactions among several types of cells. A noticeable aspect of skeletal muscle biology is the drastic cell–cell communication changes that occur in multiple scenarios.
So-ichiro Fukada   +2 more
doaj   +1 more source

Effects of inhibiting mTOR with rapamycin on behavior, development, neuromuscular physiology and cardiac function in larval Drosophila

open access: yesBiology Open, 2019
Rapamycin and other mTOR inhibitors are being heralded as possible treatments for many human ailments. It is currently being utilized clinically as an immunomodulator after transplantation procedures and as a treatment for certain forms of cancer, but it
Samuel Potter   +7 more
doaj   +1 more source

Homer 1 genotype AA variant relates to congenital splay leg syndrome in piglets by repressing Pax7 in myogenic progenitors

open access: yesFrontiers in Veterinary Science, 2023
IntroductionPorcine congenital splay leg syndrome (PCS) is a major birth defect in piglets, resulting in lameness and high mortality rates. The multifactorial pathogenesis of PSC is not well understood but includes a polygenic inheritance.MethodsHere, in
Toni Schumacher   +3 more
doaj   +1 more source

Determination and Comparison of Physical Meat Quality Parameters of Percidae and Salmonidae in Aquaculture

open access: yesFoods, 2020
Although aquaculture has been the fastest growing food sector for decades, there are no standardized parameters for most of the fish species regarding physical meat quality.
Katrin Komolka   +5 more
doaj   +1 more source

Effects of temperature on proliferation of myoblasts from donor piglets with different thermoregulatory maturities

open access: yesBMC Molecular and Cell Biology, 2021
Background Climate change and the associated risk for the occurrence of extreme temperature events or permanent changes in ambient temperature are important in the husbandry of farm animals.
Katharina Metzger   +4 more
doaj   +1 more source

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