Results 71 to 80 of about 920,865 (221)

Laryngeal Cryotherapy for Neurogenic Cough: Safety, Feasibility, and Prospective Outcomes

The Laryngoscope, EarlyView.
A prospective clinical trial investigated the safety and clinical outcomes of office‐based selective laryngeal cryotherapy for patients with refractory chronic cough. Patient were followed for 6 months posttreatment and had durable improvement in cough severity index and urge‐to‐cough scores and no serious long term adverse effects.
Shumon I. Dhar, Eric Allen, Yun‐Lun Liu, Alexandra D. D'Oto, Rishi Suresh, Adrianna Shembel, Ted Mau   +6 more
wiley   +1 more source

The time course of changes in the myonuclear domain during denervation in young-adult and old rat gastrocnemius muscle [PDF]

, 2011
If myonuclear loss initiates muscle wasting, it should precede the loss of muscle mass. As aging affects muscle plasticity, the time-course of muscle atrophy during disuse may differ between young and old animals.
Jaspers, R.T., Richard T. Jaspers, Hans Degens, van der Meer, S.F., van der Meer, S.F.T., Degens, Hans, Jones, David A, Degens, H., van der Meer, Sander, Jones, D.A., Jaspers, Richard, David A. Jones, Sander F.T. van der Meer   +12 more
core   +1 more source

Cranial Vault and Scalp Reconstruction Utilizing Anterolateral Thigh Free Tissue Transfer

The Laryngoscope, EarlyView.
The anterolateral thigh free flap with perforator harvest and minimal access recipient vessel procurement technique offers an adaptable and effective reconstructive option for a wide variety of complex scalp and cranial vault defects. There were no significant differences in outcomes or complications of the three flap types analyzed (fasciocutaneous ...
Conrad Blunck, Stephen P. Hadford, Lacey Magee, Derek Vos, Dane J. Genther, Sarah W. Liu, Michael A. Fritz, Peter J. Ciolek   +7 more
wiley   +1 more source

Therapeutic potential of omaveloxolone in counteracting muscle atrophy post-denervation: a multi-omics approach

Journal of Translational Medicine
Background Muscle atrophy caused by denervation is common in neuromuscular diseases, leading to loss of muscle mass and function. However, a comprehensive understanding of the overall molecular network changes during muscle denervation atrophy is still ...
Sulong Wang, Xin Yang, Kai Liu, Debin Xiong, Ainizier Yalikun, Yimurang Hamiti, Aihemaitijiang Yusufu   +6 more
doaj   +1 more source

GADD45A is a protective modifier of neurogenic skeletal muscle atrophy

JCI Insight, 2021
Neurogenic muscle atrophy is the loss of skeletal muscle mass and function that occurs with nerve injury and in denervating diseases, such as amyotrophic lateral sclerosis.
Jeffrey T. Ehmsen, Riki Kawaguchi, Damlanur Kaval, Anna E. Johnson, Daniel Nachun, Giovanni Coppola, Ahmet Höke   +6 more
doaj   +1 more source

Novel Injectable Supports Long‐Term Recurrent Laryngeal Nerve and Partial Peripheral Nerve Repair

The Laryngoscope, EarlyView.
Following recurrent laryngeal nerve transection in C57BL/6 mice, intramuscular Agrin, neuregulin‐1, and acetylcholine treatment of the thyroarytenoid muscle supported functional reinnervation and preservation of neuromuscular structure at 84 days.
Aditya Bhatt, William Boswell, Elena Kennedy, Sunjay Anekal, Emma Mazurek, Ananya Tadikonda, Christopher Rafalko, Jasmine Strelow, Isaac Shipchandler, Patrick R. Finnegan, Stacey Halum   +10 more
wiley   +1 more source

The TWEAK-Fn14 system is a critical regulator of denervation-induced skeletal muscle atrophy in mice [PDF]

, 2010
Skeletal muscle atrophy occurs in a variety of clinical settings, including cachexia, disuse, and denervation. Inflammatory cytokines have been shown to be mediators of cancer cachexia; however, the role of cytokines in denervation- and immobilization ...
makonchuk, denys, Bhatnagar, S, David J. Glass, Kumar, A, Lach-Trifilieff, E, li, hong, Li, H, Glass, DJ, Ashok Kumar, Shephali Bhatnagar, Makonchuk, DY, kumar, ashok, Bhatnagar, Shephali, Glass, David, Sandrine Wauters, Ashwani Mittal, Akhilesh Kumar, Estelle Lach-Trifilieff, Denys Y. Makonchuk, Mittal, Ashwani, Wauters, Sandrine, Trifilieff, Estelle, Hong Li, Wauters, S, Mittal, A   +24 more
core   +1 more source

JAK2 Variant and Parkinsonian Syndromes: Coincidence or Pathophysiological Link?

Movement Disorders Clinical Practice, EarlyView.
Abstract Background JAK2 variants are a hallmark of myeloproliferative neoplasms (MPNs), including polycythemia vera and essential thrombocythemia. These disorders are often associated with thrombotic and inflammatory complications. From a movement disorder perspective, chorea is a rare but well‐recognized neurological occurrence in this context ...
Elena Ardila Jurado, Koustubh Bavdhankar, Divyani Garg, Francesca Magrinelli, Huw R. Morris, Kailash P. Bhatia   +5 more
wiley   +1 more source

The miR-206-3p/Cpeb1 axis delays acetylcholine receptor degradation and preserves neuromuscular junction stability in denervation-induced muscle atrophy

Cellular and Molecular Life Sciences
Peripheral nerve injury leads to progressive neuromuscular junction (NMJ) destabilization and acetylcholine receptor (AChR) degradation, which are critical drivers of denervation-induced muscle atrophy and impaired motor recovery.
Guohua Jiang, Long Li, Yanhua Wang, Tianjing Zhao, Hao Guo, Han Yan, Jianwen Xu, Canjun Zeng, Yijun Liu   +8 more
doaj   +1 more source

Electrical Modalities in the Rehabilitation of Peripheral Nerve Injuries: State of the Literature and Current Clinical Applications

Muscle &Nerve, EarlyView.
ABSTRACT Peripheral nerve injuries (PNIs) are a common cause of long‐term motor and sensory disability despite advances in microsurgical repair. Functional recovery following PNI depends not only on axonal regeneration, but also on preservation of distal nerve pathways, maintenance of neuromuscular junction integrity, prevention of irreversible muscle ...
Sarah M. Smith, Kirsten M. Schlosser, Ranee Munaim, Stephanie H. Vu, JulieAnn H. Uh, Yusha K. Liu   +5 more
wiley   +1 more source