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Muscle Differentiation in Anencephaly

Developmental Medicine & Child Neurology, 1973
‡Professor of Human Genetics, University Department of Human Genetics, Western General Hospital, Edinburgh EH4 2XUSUMMARYWhen adult human muscle is deprived of its motor nerve supply the fibres atrophy and die. In anencephaly, there is a disturbance in the development of the central nervous system at an early stage, yet the limb muscles are well‐formed.
J, Toop, J N, Webb, A E, Emery
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Muscle differentiation and macromolecular synthesis

Journal of Cellular Physiology, 1968
Cytodifferentiation of skeletal muscle has been studied in cell cultures derived from leg muscle of 12-day chicken embryos. Myogenesis in cell culture closely simulates myogenesis in vivo, but is more highly synchronized. Massive cell fusion occurs in control cultures between the second and third days in vitro, during which time most of the myoblasts ...
J R, Coleman, A W, Coleman
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Lung smooth muscle differentiation

The International Journal of Biochemistry & Cell Biology, 1998
The vascular and visceral smooth muscle tissues of the lung perform a number of tasks that are critical to pulmonary function. Smooth muscle function often is compromised as a result of lung disease. Though a great deal is known about regulation of smooth muscle cell replication and cell and tissue contractility, much less is understood regarding the ...
R B, Low, S L, White
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IGFS and Muscle Differentiation

1994
The Role of IGFs in Myogenesis. Thus we are now convinced that the control of myogenesis by IGFs is a general phenomenon that occurs in all skeletal muscle cells, whether or not IGFs are added to the "differentiation" medium. We believe that several medium components contribute to the suppression of IGF-II expression in myoblasts incubated in high ...
J R, Florini   +3 more
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Histochemical characterization of muscle differentiation

Developmental Biology, 1970
Abstract A histochemical study of fiber differentiation was conducted on the longissimus muscle of pigs varying in age from 1 day to approximately 24 weeks. The longissimus, as well as other muscles of the pig, is favorable for developmental studies because of the characteristic arrangement of the three fiber types within the fascicles ...
C C, Cooper   +3 more
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Muscle differentiation

Current Opinion in Cell Biology, 1992
Recent studies indicate that vertebrate skeletal muscle originates from two distinct populations of muscle precursor cells formed in early embryogenesis. Divergent patterns of expression for the myoD family of myogenic regulatory genes in different vertebrate embryos suggest some functional redundancy amongst the myogenic factors. Initial gene knockout
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Tumors with Smooth Muscle Differentiation

Dermatologic Surgery, 1996
In the classification of tumors of soft tissue, modern schemes describe tumors by the normal adult tissue type the tumor resembles. Thus, tumors are described as smooth muscle tumors if the cells are differentiating towards smooth muscle. We may infer that in fact the tumor arose from smooth muscle, but this is only an inference.
J M, Spencer, R A, Amonette
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Muscle cell differentiation

Current Opinion in Cell Biology, 1989
The appeal of myogenic differentiation as a model developmental system derives in part from the complexity of regulatory steps required to account for the diversity of muscle structure and function. The intricate patterns of contractile tissue formation in the adult animal depend on the orderly progression of molecular signals that lead primordial ...
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Differential diagnosis of muscle calcification

Clinical Imaging, 2019
We report the case of a 36 year old male who demonstrated extensive high attenuation in the muscles of the chest wall and neck on a noncontrast chest CT. The high attenuation in the musculature was due to calcium, sequela from a recent episode of rhabdomyolysis.
Elizabeth, Lee   +2 more
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TRAF2 expression in differentiated muscle

Journal of Cellular Biochemistry, 1998
Recent data involving traf2 knockout mice have suggested a necessity of the protein in viability of skeletal muscle tissue. traf2 -/- mice are born with decreased muscle mass that is hypothesized to be due to the increased circulating tumor necrosis factor in these mice.
MacLachlan T. K., Giordano A.
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