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MiR-208b Regulates the Conversion of Skeletal Muscle Fiber Types by Inhibiting Mettl8 Expression

open access: yesFrontiers in Genetics, 2022
Skeletal muscle, the main source of animal meat products, contains muscle fiber as a key unit. It is well known that transformation takes place between different types of muscle fibers, however, the conversion mechanism is not clear. In a previous study,
Xiang Li   +3 more
doaj   +1 more source

Aging of Skeletal Muscle Fibers [PDF]

open access: yesAnnals of Rehabilitation Medicine, 2015
Aging has become an important topic for scientific research because life expectancy and the number of men and women in older age groups have increased dramatically in the last century. This is true in most countries of the world including the Republic of Korea and the United States. From a rehabilitation perspective, the most important associated issue
Miljkovic, Natasa   +3 more
openaire   +2 more sources

mTORC1 mediates fiber type-specific regulation of protein synthesis and muscle size during denervation

open access: yesCell Death Discovery, 2021
Skeletal muscle denervation occurs in diverse conditions and causes severe muscle atrophy. Signaling by mammalian target of rapamycin complex 1 (mTORC1) plays a central role in the maintenance of skeletal muscle mass by regulating net protein balance ...
Jae-Sung You   +4 more
doaj   +1 more source

Targeted myostatin loss-of-function mutation increases type II muscle fibers in Meishan pigs

open access: yesJournal of Integrative Agriculture, 2022
Myostatin (MSTN) is a negative regulator of skeletal muscle growth and development. The skeletal muscle in MSTN−/– mice is significantly hypertrophied, with muscle fiber type II increasing significantly while muscle fiber type I decreasing.
Li-li QIAN   +7 more
doaj   +1 more source

Human and Rodent Skeletal Muscles Express Angiotensin II Type 1 Receptors

open access: yesCells, 2020
Abundant evidence reveals that activation of the renin-angiotensin system promotes skeletal muscle atrophy in several conditions including congestive heart failure, chronic kidney disease, and prolonged mechanical ventilation. However, controversy exists
Rafael Deminice   +6 more
doaj   +1 more source

Mechanisms of exercise-induced preconditioning in skeletal muscles

open access: yesRedox Biology, 2020
Endurance exercise training promotes numerous biochemical adaptations within skeletal muscle fibers culminating into a phenotype that is safeguarded against numerous perils including doxorubicin-induced myopathy and inactivity-induced muscle atrophy ...
Scott K. Powers   +3 more
doaj   +1 more source

A Combined Differential Proteome and Transcriptome Profiling of Fast- and Slow-Twitch Skeletal Muscle in Pigs

open access: yesFoods, 2022
Skeletal muscle fiber types can contribute in part to affecting pork quality parameters. Biceps femoris (Bf) (fast muscle or white muscle) and Soleus (Sol) (slow muscle or red muscle) are two typical skeletal muscles characterized by obvious muscle fiber
Wei Wei   +7 more
doaj   +1 more source

Mitochondrial Properties in Skeletal Muscle Fiber

open access: yesCells, 2023
Mitochondria are the primary source of energy production and are implicated in a wide range of biological processes in most eukaryotic cells. Skeletal muscle heavily relies on mitochondria for energy supplements. In addition to being a powerhouse, mitochondria evoke many functions in skeletal muscle, including regulating calcium and reactive oxygen ...
Han Dong, Shih-Yin Tsai
openaire   +3 more sources

Redox signaling regulates skeletal muscle remodeling in response to exercise and prolonged inactivity

open access: yesRedox Biology, 2022
Skeletal muscle fibers are malleable and undergo rapid remodeling in response to increased contractile activity (i.e., exercise) or prolonged periods of muscle inactivity (e.g., prolonged bedrest).
Scott K. Powers, Matthew Schrager
doaj   +1 more source

Mechanical Properties of Single Muscle Fibers: Understanding Poor Muscle Quality in Older Adults with Diabetes [PDF]

open access: yesAnnals of Geriatric Medicine and Research, 2020
Background While aging causes muscle weakness, type 2 diabetes mellitus (T2DM) is also considered a high-risk factor for the induction of skeletal muscle weakness.
Eun-Jeong Lee   +4 more
doaj   +1 more source

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