Results 51 to 60 of about 5,696,273 (256)
The Effect of Pax3 Over-expression on Myoblast Function [PDF]
, 2009 The paired-box transcription factor 3 (Pax3), is a powerful myogenic regulatory factor during embryo-myogenesis. The expression of Pax3 is involved in determining somitic cell fate, resulting in the formation of the first differentiated muscle, the ...
Brijs, Erik
core
Advanced Functional Materials, EarlyView.This study presents a magneto‐mechanical strategy that incorporates FP@MSCs into an aligned PCL/GelMA nerve guidance conduit. Magnetic stimulation increases membrane tension in FP@MSCs, triggering cytoskeletal remodeling, Schwann cell‐like differentiation, and TIMP1 secretion. TIMP1 activates ITGB1/CD63–FAK signaling in NE‐4C cells, increasing membrane
Xinyu Zhu +14 more
wiley +1 more source
Pro-myogenic small molecules revealed by a chemical screen on primary muscle stem cells
Skeletal Muscle, 2020 Satellite cells are the canonical muscle stem cells that regenerate damaged skeletal muscle. Loss of function of these cells has been linked to reduced muscle repair capacity and compromised muscle health in acute muscle injury and congenital ...
Sean M. Buchanan +9 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.FeS‐VA@lanifibranor (FVL), an activated hepatic stellate cell (aHSC)‐targeted nanoplatform comprising vitamin A‐functionalized two‐dimensional iron sulfide nanosheets and lanifibranor, is engineered for precision therapy of liver fibrosis. FVL suppresses the TGF‐β signaling pathway by inhibiting SMAD2/3 phosphorylation and induces ferroptosis in aHSCs,
Yinuo Yang +11 more
wiley +1 more source
A Coupled Mechanobiological Model of Muscle Regeneration In Cerebral Palsy
Frontiers in Bioengineering and Biotechnology, 2021 Cerebral palsy is a neuromusculoskeletal disorder associated with muscle weakness, altered muscle architecture, and progressive musculoskeletal symptoms that worsen with age. Pathological changes at the level of the whole muscle have been shown; however,
Stephanie Khuu +3 more
doaj +1 more source
Optical Detection of Cellular Signals at Material Interfaces
Advanced Healthcare Materials, EarlyView.Emerging functional materials are transforming optical detection of cellular signals. This review highlights optical techniques that exploit the unique optical properties of diverse materials to detect and quantify cellular electrical, chemical, and mechanical signals, and discusses key opportunities and challenges.
Xuchen Ren +5 more
wiley +1 more source
Synthesis of extracellular matrix components by human ciliary muscle cells in culture [PDF]
, 1992 The production and spatial organization of connective tissue components in ciliary muscle cell cultures was studied with immunohistochemical and ultrastructural methods.
Baur, A. +2 more
core +1 more source
Advanced Materials, EarlyView.TESCLA (tubular electromagnetic soft conformal linear actuator) combines liquid‐metal solenoids and compliant magnetic composites to achieve large‐stroke bidirectional actuation with continuous bending. Integrated inductance‐based self‐sensing enables proprioceptive position estimation without external sensors, providing a versatile platform for soft ...
Yeongjin Choi +3 more
wiley +1 more source
A simplified but robust method for the isolation of avian and mammalian muscle satellite cells
BMC Cell Biology, 2012 Background Current methods of isolation of muscle satellite cells from different animal species are highly variable making inter-species comparisons problematic.
Baquero-Perez Belinda +3 more
doaj +1 more source
CONSTRUCTIVE TISSUE REMODELING BY EXTRACELLULAR MATRIX BIOSCAFFOLDS WITHIN THE AGING SKELETAL MUSCLE MICROENVIRONMENT [PDF]
, 2013 Adult mammalian skeletal muscle tissue retains inherent regenerative capability in response to injury. This regenerative response is contingent upon an activated progenitor cell population and a temporal transition from pro-inflammatory M1 to ...
Sicari, Brian
core