Results 11 to 20 of about 117,705 (306)

Chemotherapy-induced muscle wasting: an update

open access: yesEuropean Journal of Translational Myology, 2018
The majority of cancers are associated to cachexia, a severe form of weight loss mostly accounted for by skeletal muscle wasting. Cancer patients are often treated with chemotherapy, whose side effects are at times neglected or underestimated ...
Dario Coletti
doaj   +4 more sources

Muscle-tendon cross talk during muscle wasting [PDF]

open access: yesAmerican Journal of Physiology-Cell Physiology, 2021
In organisms from flies to mammals, the initial formation of a functional tendon is completely dependent on chemical signals from muscles (myokines). However, how myokines affect the maturation, maintenance, and regeneration of tendons as a function of age is completely unstudied.
Alec M. Avey, Keith Baar
openaire   +4 more sources

MicroRNAs in muscle wasting [PDF]

open access: yesJournal of Cachexia, Sarcopenia and Muscle, 2018
Skeletal muscle makes up approximately 40% of the total body mass; it is essential in providing structural support, to regulate motion and as an energy store, thereby playing a major role in the overall metabolism. Skeletal muscle retains a high plasticity in order to respond to various stimuli, which subsequently lead to changes in gene transcription ...
Tsuyoshi Suzuki, Jochen Springer
doaj   +5 more sources

Association between histological diaphragm atrophy and ultrasound diaphragm expiratory thickness in ventilated patients

open access: yesJournal of Intensive Care, 2022
Background Diaphragm fiber atrophy has been evidenced after short periods of mechanical ventilation (MV) and related to critical illness-associated diaphragm weakness.
Irene Dot   +10 more
doaj   +1 more source

Effects of Exercise Training on Circulating Biomarkers of Endothelial Function in Pulmonary Arterial Hypertension

open access: yesBiomedicines, 2023
Introduction: In stable patients with pulmonary arterial hypertension (PAH), pulmonary rehabilitation (PR) is an effective, safe and cost-effective non-pharmacological treatment.
Diego A. Rodríguez-Chiaradía   +14 more
doaj   +1 more source

The role of extracellular vesicles in skeletal muscle wasting

open access: yesJournal of Cachexia, Sarcopenia and Muscle, 2023
Skeletal muscle wasting is a complicated metabolic syndrome accompanied by multiple diseases ranging from cancer to metabolic disorders and infectious conditions. The loss of muscle mass significantly impairs muscle function, resulting in poor quality of
Xiaohui Zhang, Yanxia Zhao, Wei Yan
doaj   +1 more source

CHAC1 inactivation is effective to preserve muscle glutathione but is insufficient to protect against muscle wasting in cachexia.

open access: yesPLoS ONE, 2023
Muscle wasting is one of the main characteristics of cachexia associated with cancer and other chronic diseases and is often exacerbated by antineoplastic agents.
Junjie Li   +7 more
doaj   +1 more source

Mitochondrial Dysfunction Is a Common Denominator Linking Skeletal Muscle Wasting Due to Disease, Aging, and Prolonged Inactivity

open access: yesAntioxidants, 2021
Skeletal muscle is the most abundant tissue in the body and is required for numerous vital functions, including breathing and locomotion. Notably, deterioration of skeletal muscle mass is also highly correlated to mortality in patients suffering from ...
Hayden W. Hyatt, Scott K. Powers
doaj   +1 more source

Sarcopenia and risk of infection in adult heart transplant recipients in Japan

open access: yesESC Heart Failure, 2022
Aims Heart transplantation (HT) is an effective therapeutic option for end‐stage heart failure. Infection is a major cause of morbidity and mortality after HT.
Masaki Tsuji   +12 more
doaj   +1 more source

Nutrient modulation in the management of disease-induced muscle wasting: evidence from human studies [PDF]

open access: yes, 2017
Purpose of review: In addition to being essential for movement, skeletal muscles act as both a store and source of key macronutrients. As such, muscle is an important tissue for whole body homeostasis, undergoing muscle wasting in times of starvation ...
Atherton, Philip J.   +2 more
core   +2 more sources

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