Results 21 to 30 of about 115,632 (206)

Incidence of muscle wasting in the critically ill: a prospective observational cohort study

open access: yesScientific Reports, 2023
Loss of muscle mass occurs rapidly during critical illness and negatively affects quality of life. The incidence of clinically significant muscle wasting in critically ill patients is unclear.
Ondrej Hrdy   +5 more
doaj   +1 more source

Nutrient modulation in the management of disease-induced muscle wasting: evidence from human studies [PDF]

open access: yes, 2017
Purpose of review: In addition to being essential for movement, skeletal muscles act as both a store and source of key macronutrients. As such, muscle is an important tissue for whole body homeostasis, undergoing muscle wasting in times of starvation ...
Atherton, Philip J.   +2 more
core   +2 more sources

Myopenia-a new universal term for muscle wasting [PDF]

open access: yes, 2011
A universal term describing the presence of clinically relevant muscle wasting that warrants medical intervention is required. The term sarcopenia might be used in this context.
Kenneth Fearon   +2 more
core   +1 more source

HCT116 colorectal liver metastases exacerbate muscle wasting in a mouse model for the study of colorectal cancer cachexia [PDF]

open access: yes, 2020
Colorectal cancer (CRC) is often accompanied by formation of liver metastases (LM) and skeletal muscle wasting, i.e. cachexia. Despite affecting the majority of CRC patients, cachexia remains underserved, understudied and uncured.
Bonetto, Andrea   +3 more
core   +1 more source

Micro(RNA)-managing muscle wasting [PDF]

open access: yesJournal of Applied Physiology, 2019
Progressive skeletal muscle wasting is a natural consequence of aging and is common in chronic and acute diseases. Loss of skeletal muscle mass and function (strength) often leads to frailty, decreased independence, and increased risk of hospitalization.
Anthony J. Sannicandro   +2 more
openaire   +2 more sources

Myocardial Dysfunction in an Animal Model of Cancer Cachexia [PDF]

open access: yes, 2011
Aims Fatigue is a common occurrence in cancer patients regardless of tumor type or anti-tumor therapies and is an especially problematic symptom in persons with incurable tumor disease.
Crawford, Danielle   +7 more
core   +2 more sources

A shared mechanism of muscle wasting in cancer and Huntington's disease. [PDF]

open access: yes, 2015
Skeletal muscle loss and dysfunction in aging and chronic diseases is one of the major causes of mortality in patients, and is relevant for a wide variety of diseases such as neurodegeneration and cancer.
Constantinou C   +4 more
core   +2 more sources

Hypoxia Aggravates Inactivity-Related Muscle Wasting [PDF]

open access: yesFrontiers in Physiology, 2018
Frontiers in physiology 9, 494 (2018).
Tadej Debevec   +9 more
openaire   +6 more sources

The bone morphogenetic protein axis is a positive regulator of skeletal muscle mass [PDF]

open access: yes, 2013
Although the canonical transforming growth factor β signaling pathway represses skeletal muscle growth and promotes muscle wasting, a role in muscle for the parallel bone morphogenetic protein (BMP) signaling pathway has not been defined. We report,
Amthor   +75 more
core   +2 more sources

Growth differentiation factor 11 induces skeletal muscle atrophy via a STAT3-dependent mechanism in pulmonary arterial hypertension

open access: yesSkeletal Muscle, 2022
Skeletal muscle wasting is a clinically remarkable phenotypic feature of pulmonary arterial hypertension (PAH) that increases the risk of mortality.
Guiling Xiang   +7 more
doaj   +1 more source

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