Results 141 to 150 of about 11,554 (309)

KAT2A Deficiency Suppresses Lung Cancer Progression by Downregulating MYC Through Decreasing MYC Succinylation

Cancer Science, EarlyView.
ABSTRACT Succinylation has been shown to promote lung cancer development, but its mechanism remains incompletely understood. KAT2A, a succinyltransferase, acts as an oncogene in multiple cancers, but its role in mediating lung cancer progression is unclear.
Junping Li, Feng Zhao, Zhongchao Wang, Shaojun Yang, Zhichao Lu, Xiaoyan Li, Jincheng Song, Zhaoxia Dai   +7 more
wiley   +1 more source

Guidelines for the assessment and control of mutagenic impurities in pharmaceuticals. [PDF]

Genes Environ
Honma M.
europepmc   +1 more source

Contact Allergy to Ingredients of Hair Cosmetics Associated with Occupational and Non‐Occupational Exposure—Trends from 1995 to 2020 in Central Europe, with or without Regulation

Contact Dermatitis, EarlyView.
Among 2678 female hairdressers and 6244 female consumers with contact dermatitis suspected to be related to use of hair cosmetics, including dyes, patch tested in the IVDK between 1995 and 2020, diverging contact allergy trends were observed. In the case of toluene‐2,5‐diamine (PTD) shown in the figure, sensitization was at a stable, high level in ...
Wolfgang Uter, Jakob Ferløv Baselius Schwensen, Brunhilde Blömeke, Olaf Gefeller, Swen M. John, Cara Bieck, Steffen Schubert   +6 more
wiley   +1 more source

Application of error-corrected sequencing technologies for in vivo regulatory mutagenicity assessment. [PDF]

Regul Toxicol Pharmacol
Yauk CL, Lynch AM, Dobrovolsky VN, Schuler M, Smith-Roe SL, Fitzgerald D, Higgins J, Honarvar N, Le Curieux F, Matsumura S, Minocherhomji S, Recio L, Salk JJ, Sugiyama KI, Suzuki T, Wills JW, Marchetti F.   +16 more
europepmc   +1 more source

Mutagenicity tests.

Japan journal of water pollution research, 1984
openaire   +2 more sources

Red era: Dyeing yak hair fibres red with in situ generated silver nanoparticles using silver nitrate and a flavonoid‐containing plant extract

Coloration Technology, EarlyView.
Abstract Plants and their extracts have been used for dyeing fabrics, skin and hair for thousands of years and have been experiencing a revival in the last years due to increasing health risks arising from oxidative hair dye precursors. We developed a novel two‐step method to dye keratin fibres based on in situ formed silver nanoparticles including a ...
Julia K. Hachmann, Jule M. Sauler, Charlotte Ruhmlieb, Volkmar Vill, Fabian Straske   +4 more
wiley   +1 more source

SAR Modeling to Predict Ames Mutagenicity Across Different <i>Salmonella typhimurium</i> Strains. [PDF]

Pharmaceuticals (Basel)
Dmitriev AV, Lagunin AA, Rudik AV, Savosina PI, Druzhilovskiy DS, Filimonov DA, Poroikov VV.   +6 more
europepmc   +1 more source

Mutagenic effects of tributyltin and inorganic lead (Pb II) on the fish H. malabaricus as evaluated using the comet assay and the piscine micronucleus and chromosome aberration tests [PDF]

, 2004
Marcos Vinícius Mocellin Ferraro, Alberto Sérgio Fenocchio, Mário Sérgio Mantovani, Ciro Alberto de Oliveira Ribeiro, Marta Margarete Cestari   +4 more
openalex   +1 more source

Identification and Phylogenetic Characterisation of Novel Adeno‐Associated Virus Capsids in Non‐Human Primate Tissues

Cell Proliferation, EarlyView.
AAV's widespread application is currently confronting critical challenges. This study established a systematic framework of ‘natural discovery–evolutionary analysis–functional optimization’, providing a new paradigm for the development of next‐generation AAV vectors with clinical‐grade tissue specificity, low immunogenicity, and cross‐species ...
Liyu Zhu, Kai Xu, Yali Ding, Kailun Liu, Jing Liu, Zongren Hou, Rui Niu, Ning Yang, Hualing Qin, Baoyang Hu, Ying Zhang, Wei Li   +11 more
wiley   +1 more source

Chemical components of electric vehicle and internal combustion engine vehicle fire smoke and their mutagenic effects. [PDF]

Environ Sci Pollut Res Int
Kim YH, Nored A, Horn GP, Kesler RM, Barowy A, Schraiber A, Gaudet B, Mayer AC, Niemeier-Walsh M, Fent KW, Kovalcik K, Pancras JP, Gilmour MI.   +12 more
europepmc   +1 more source