Results 31 to 40 of about 13,277,354 (332)

Social context prevents heat hormetic effects against mutagens during fish development

open access: yesFEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere   +5 more
wiley   +1 more source

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren   +16 more
wiley   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

The mutagenicity of benzimidazole and benzimidazole derivatives III . The influence of the 2-substituent in benzimidazole on the mutagenic activity

open access: yesCHIMIA, 1973
A number of 2-substituted benzimidazoles has been prepared and the compounds were characterized by their physico-chemical and spectral properties. - Mutagenicity tests with two strains of Salmonella typhimurium revealed that on one hand the mutagenic ...
J.P. Seiler, H. Limacher
doaj   +1 more source

Powder Metallurgy Preparation of Metastable β Ti–Cr–Ge Alloys for Medical Applications

open access: yesAdvanced Engineering Materials, EarlyView.
This study develops metastable β Ti–Cr–Ge alloys using powder metallurgy for biomedical implants. The Ti–10Cr–2Ge alloy exhibits superior mechanical performance with high yield strength (>1100 MPa), low Young's modulus (<85 GPa), and excellent strain hardening behavior.
Teddy Sjafrizal   +3 more
wiley   +1 more source

Biological properties of a novel coladerm-beta glucan membrane.In vitro assessment using human fibroblasts

open access: yesBiomedical Papers, 2015
Aim: The purpose of this study was to prepare a coladerm-beta glucan membrane (CBGM) and to evaluate its biocompatibility, cytotoxicity, antimicrobial activity, genotoxicity and mutagenicity.
Sona Jantova   +3 more
doaj   +1 more source

Evaluation of transcriptional fusions with green fluorescent protein versus luciferase as reporters in bacterial mutagenicity tests.

open access: yesMutagenesis, 1999
A bacterial plasmid was constructed on which the regulatory region of the umuC gene of Escherichia coli was fused to the coding sequence of the green fluorescent protein gene (gfp) from the jellyfish Aequorea victoria.
Timothy Justus, S. M. Thomas
semanticscholar   +1 more source

A Visible Light‐Responsive Hydrogel to Study the Effect of Dynamic Tissue Stiffness on Cellular Mechanosensing

open access: yesAdvanced Functional Materials, EarlyView.
A visible light‐responsive polyacrylamide‐azobenzene hydrogel enables safe, reversible stiffness control for studying cell mechanobiology without harmful UV exposure. This approach reveals stem cells respond rapidly to mechanical changes, showing altered shape and protein distribution within one hour.
Aafreen Ansari   +11 more
wiley   +1 more source

Copper‐based Materials for Photo and Electrocatalytic Process: Advancing Renewable Energy and Environmental Applications

open access: yesAdvanced Functional Materials, EarlyView.
Cu‐based catalysts as a cornerstone in advancing sustainable energy technologies are fully reviewed in this manuscript, highlighting their potential in photo‐ and electrocatalysis. It includes metallic copper, copper oxides, copper sulfides, copper halide perovskites, copper‐based metal–organic frameworks (MOFs), and covalent organic frameworks (COFs),
Jéssica C. de Almeida   +16 more
wiley   +1 more source

Genotoxicity of Di (2-ethyl hexyl) phthalate

open access: yesZhongguo shipin weisheng zazhi, 2022
ObjectiveTo assess the genotoxicity of Di(2-ethylhexyl) phthalate (DEHP).MethodsA series of guideline-compliant assays were performed to evaluate mutagenicity, chromosomal or DNA damage of DEHP, including Ames test, in vitro mammalian chromosome ...
LI Juntao   +9 more
doaj   +1 more source

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