Results 61 to 70 of about 12,851 (183)
Transposable elements: Functional aspects and applications as drivers of crop innovation
Abstract Transposable elements (TEs), which were once relegated to the status of genomic parasites, are today accepted as important agents of plant genome evolution and adaptation. This review integrates evidence pointing to their dual function as drivers of genetic diversity and instability, with a focus on their contribution to phenotypic innovation,
Flávia Layse Belém Medeiros +12 more
wiley +1 more source
The role of mitochondrial DNA mutations in organismal fitness and lifespan have been studied in mitochondrial mutator models with varying results. Here, the authors generate a new APOBEC1 expression-based Drosophila mutator model and show that it has ...
Simonetta Andreazza +15 more
doaj +1 more source
Abstract Phytophthora crown rot, caused by Phytophthora cactorum, is a soilborne disease with broad impacts on cultivated strawberry (Fragaria × ananassa). A resistance locus, RPc2, was previously identified in octoploid strawberries, but the underlying genomic architecture and causal genes remained uncharacterized.
Hyeondae Han +14 more
wiley +1 more source
Abstract Meiotic recombination is essential for generating genetic diversity, driving plant evolution, and enabling crop improvement, yet its uneven distribution across genomes constrains breeding efforts. Here, we investigated the multi‐omic landmarks that shape the recombination landscape in Brassica napus by integrating epigenomic, genomic, and ...
Jose A. Montero‐Tena +6 more
wiley +1 more source
Abstract Maize (Zea mays L.) kernel mutants are valuable tools for investigating kernel development. In this study, we employed ethyl methanesulfonate (EMS) mutagenesis of pollen on five inbred lines, which displayed varying performance after treatment. Over 400 independent kernel mutants were generated, showing a wide range of defects in both type and
Haixiao Dong +10 more
wiley +1 more source
Detection of mutator phenotype in Brazilian patients with acute and chronic myeloid leukemia
The multisteps of tumorigenesis involve the classic chromosomal instability and the mutator phenotype pathways featured by a predisposition to acquire mutations in tumor suppressor genes and oncogenes.
Flávio Monteiro Ayres +3 more
doaj +1 more source
There is a great need for approaches to control how species evolve in response to environmental changes, particularly in complex microbiomes. The feasibility is often met with scepticism due to the multitude of open questions and high dimensionality of community eco‐evolutionary dynamics.
Thomas Scheuerl, Damian W. Rivett
wiley +1 more source
Carcinogenesis is a process of somatic evolution. Previous models of stem and transient amplifying cells in epithelial proliferating units like colonic crypts showed that intermediate numbers of stem cells in a crypt should optimally prevent progression ...
David Birtwell +2 more
doaj +1 more source
Summary Southern leaf blight (SLB), caused by the necrotrophic fungus Cochliobolus heterostrophus, is a major foliar disease of maize (Zea mays) world‐wide. A genome‐wide association study was performed to dissect the genetic basis of SLB resistance in maize. Functional validation was performed using mutant and transgenic analyses.
Tao Zhong +8 more
wiley +1 more source

