Results 61 to 70 of about 12,851 (183)

Transposable elements: Functional aspects and applications as drivers of crop innovation

open access: yesCrop Science, Volume 66, Issue 2, March/April 2026.
Abstract Transposable elements (TEs), which were once relegated to the status of genomic parasites, are today accepted as important agents of plant genome evolution and adaptation. This review integrates evidence pointing to their dual function as drivers of genetic diversity and instability, with a focus on their contribution to phenotypic innovation,
Flávia Layse Belém Medeiros   +12 more
wiley   +1 more source

Mitochondrially-targeted APOBEC1 is a potent mtDNA mutator affecting mitochondrial function and organismal fitness in Drosophila

open access: yesNature Communications, 2019
The role of mitochondrial DNA mutations in organismal fitness and lifespan have been studied in mitochondrial mutator models with varying results. Here, the authors generate a new APOBEC1 expression-based Drosophila mutator model and show that it has ...
Simonetta Andreazza   +15 more
doaj   +1 more source

Genomic architecture of the resistance to Phytophthora cactorum 2 (RPc2) locus in strawberry (Fragaria × ananassa)

open access: yesThe Plant Genome, Volume 19, Issue 1, March 2026.
Abstract Phytophthora crown rot, caused by Phytophthora cactorum, is a soilborne disease with broad impacts on cultivated strawberry (Fragaria × ananassa). A resistance locus, RPc2, was previously identified in octoploid strawberries, but the underlying genomic architecture and causal genes remained uncharacterized.
Hyeondae Han   +14 more
wiley   +1 more source

Machine learning and multi‐omic analysis reveal contrasting recombination landscape of A and C subgenomes of winter oilseed rape

open access: yesThe Plant Genome, Volume 19, Issue 1, March 2026.
Abstract Meiotic recombination is essential for generating genetic diversity, driving plant evolution, and enabling crop improvement, yet its uneven distribution across genomes constrains breeding efforts. Here, we investigated the multi‐omic landmarks that shape the recombination landscape in Brassica napus by integrating epigenomic, genomic, and ...
Jose A. Montero‐Tena   +6 more
wiley   +1 more source

Quick creation and mapping of EMS‐induced maize kernel mutants identifies classical gene ZmBT1 and novel gene ZmTOP6A

open access: yesThe Plant Genome, Volume 19, Issue 1, March 2026.
Abstract Maize (Zea mays L.) kernel mutants are valuable tools for investigating kernel development. In this study, we employed ethyl methanesulfonate (EMS) mutagenesis of pollen on five inbred lines, which displayed varying performance after treatment. Over 400 independent kernel mutants were generated, showing a wide range of defects in both type and
Haixiao Dong   +10 more
wiley   +1 more source

Detection of mutator phenotype in Brazilian patients with acute and chronic myeloid leukemia

open access: yesGenetics and Molecular Biology, 2004
The multisteps of tumorigenesis involve the classic chromosomal instability and the mutator phenotype pathways featured by a predisposition to acquire mutations in tumor suppressor genes and oncogenes.
Flávio Monteiro Ayres   +3 more
doaj   +1 more source

A Concept Using α‐Niche Evolution Within Bacterial Communities to Direct β‐Niche Evolution of Focal Species

open access: yesEnvironmental Microbiology, Volume 28, Issue 3, March 2026.
There is a great need for approaches to control how species evolve in response to environmental changes, particularly in complex microbiomes. The feasibility is often met with scepticism due to the multitude of open questions and high dimensionality of community eco‐evolutionary dynamics.
Thomas Scheuerl, Damian W. Rivett
wiley   +1 more source

The evolution of metapopulation dynamics and the number of stem cells in intestinal crypts and other tissue structures in multicellular bodies

open access: yesEvolutionary Applications, 2020
Carcinogenesis is a process of somatic evolution. Previous models of stem and transient amplifying cells in epithelial proliferating units like colonic crypts showed that intermediate numbers of stem cells in a crypt should optimally prevent progression ...
David Birtwell   +2 more
doaj   +1 more source

The maize mitogen‐activated protein kinase kinase kinase gene ZmMAPKKK45 is associated with multiple disease resistance

open access: yesNew Phytologist, Volume 249, Issue 6, Page 3003-3020, March 2026.
Summary Southern leaf blight (SLB), caused by the necrotrophic fungus Cochliobolus heterostrophus, is a major foliar disease of maize (Zea mays) world‐wide. A genome‐wide association study was performed to dissect the genetic basis of SLB resistance in maize. Functional validation was performed using mutant and transgenic analyses.
Tao Zhong   +8 more
wiley   +1 more source

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