Results 191 to 200 of about 17,684 (224)
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Bio-isoprene production using exogenous MVA pathway and isoprene synthase in Escherichia coli
Bioresource Technology, 2012In this paper, an original strategy is employed to biosynthesize the isoprene by heterologously co-expressing the Saccharomyces cerevisiae MVA pathway and isoprene synthase (IspS) from Populus alba in the Escherichia coli BL21 (DE3) strain, which was screened from three different IspS enzymes.
Jianming Yang +2 more
exaly +3 more sources
Journal of the Korean Society for Applied Biological Chemistry, 2014
Panax ginseng Meyer is one of the most important medicinal plants in Asia, and ginseng has attracted considerable attention worldwide. Triterpene saponins (ginsenosides) are the main bioactive compounds in P. ginseng. The isoprene units of triterpene are derived from the mevalonic acid (MVA) pathway.
Yong-Kyoung Kim +2 more
exaly +2 more sources
Panax ginseng Meyer is one of the most important medicinal plants in Asia, and ginseng has attracted considerable attention worldwide. Triterpene saponins (ginsenosides) are the main bioactive compounds in P. ginseng. The isoprene units of triterpene are derived from the mevalonic acid (MVA) pathway.
Yong-Kyoung Kim +2 more
exaly +2 more sources
Bioresource Technology, 2018
The multiple plasmid system, mostly relied, for heterogeneous gene expression, results in genetic instability and low mean productivity. To address this, an integration method was employed for investigating expression of heterogenous pathway in E. coli cells; where mevalonate upper pathway was found efficiently expressed.
Ali Mohsin, Meijin Guo, Hongqing Fang
exaly +3 more sources
The multiple plasmid system, mostly relied, for heterogeneous gene expression, results in genetic instability and low mean productivity. To address this, an integration method was employed for investigating expression of heterogenous pathway in E. coli cells; where mevalonate upper pathway was found efficiently expressed.
Ali Mohsin, Meijin Guo, Hongqing Fang
exaly +3 more sources
Proceedings of the 3rd International Symposium on Artificial Intelligence for Medicine Sciences, 2022
Yijun Chen, Minqi Chen, Wenjun Mao
exaly +2 more sources
Yijun Chen, Minqi Chen, Wenjun Mao
exaly +2 more sources
China Journal of Chinese Materia Medica, 2015
Methyl valerate (MVA) pathway is one of the important ways for synthesis of terpenoids. This study was based on data of the transcriptome sequencing of Magnolia officinalis, the associated genes MoACOT, MoHMGS, MoHMGR, MoMK in methyl valerate (MVA) pathway, were completed in detail by using bioinformatics methods.
Liang-ping, Zha +3 more
openaire +3 more sources
Methyl valerate (MVA) pathway is one of the important ways for synthesis of terpenoids. This study was based on data of the transcriptome sequencing of Magnolia officinalis, the associated genes MoACOT, MoHMGS, MoHMGR, MoMK in methyl valerate (MVA) pathway, were completed in detail by using bioinformatics methods.
Liang-ping, Zha +3 more
openaire +3 more sources
Network Analysis of the MVA and MEP Pathways for Isoprenoid Synthesis
Annual Review of Plant Biology, 2013Isoprenoid biosynthesis is essential for all living organisms, and isoprenoids are also of industrial and agricultural interest. All isoprenoids are derived from prenyl diphosphate (prenyl-PP) precursors. Unlike isoprenoid biosynthesis in other living organisms, prenyl-PP, as the precursor of all isoprenoids in plants, is synthesized by two ...
Eva Vranová +2 more
openaire +3 more sources
Chemico-Biological Interactions, 2023
Hepatocellular carcinoma (HCC) is one of the most common malignant tumors with high morbidity and mortality. Targeting abnormal cholesterol metabolism is a potential therapeutic direction. Therefore, more natural drugs targeting cholesterol in HCC need to be developed.
Man-Yu Xiao +9 more
openaire +2 more sources
Hepatocellular carcinoma (HCC) is one of the most common malignant tumors with high morbidity and mortality. Targeting abnormal cholesterol metabolism is a potential therapeutic direction. Therefore, more natural drugs targeting cholesterol in HCC need to be developed.
Man-Yu Xiao +9 more
openaire +2 more sources
Phytochemistry, 2011
Potato flavour is a complex trait resulting from the presence of a combination of volatile and non-volatile compounds. The aim of this work was to investigate the effect of specifically altering the volatile content of tubers and assess its impact on flavour. Tuber-specific over-expression of a potato α-copaene synthase gene resulted in enhanced levels
Wayne L, Morris +6 more
openaire +2 more sources
Potato flavour is a complex trait resulting from the presence of a combination of volatile and non-volatile compounds. The aim of this work was to investigate the effect of specifically altering the volatile content of tubers and assess its impact on flavour. Tuber-specific over-expression of a potato α-copaene synthase gene resulted in enhanced levels
Wayne L, Morris +6 more
openaire +2 more sources
Journal of Asian Natural Products Research, 2016
Celastrol is an important bioactive triterpenoid in traditional Chinese medicinal plant, Tripterygium wilfordii. Methyl Jasmonate (MJ) is a common plant hormone which can regulate the secondary metabolism in higher plants. In this study, the mevalonate (MVA) pathway genes in T. wilfordii were firstly cloned. The suspension cells of T.
Yu-Jia, Liu +7 more
openaire +2 more sources
Celastrol is an important bioactive triterpenoid in traditional Chinese medicinal plant, Tripterygium wilfordii. Methyl Jasmonate (MJ) is a common plant hormone which can regulate the secondary metabolism in higher plants. In this study, the mevalonate (MVA) pathway genes in T. wilfordii were firstly cloned. The suspension cells of T.
Yu-Jia, Liu +7 more
openaire +2 more sources
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2022
In this study, we used bioinformatic tools to analyze the 3-hydroxy-3-methylglutaryl-CoA reductase(HMGR) genes from Glycyrrhiza uralensis, Artemisia annua, and Arabidopsis thaliana. The results indicated that GuHMGR and AaHMGR contained two transmembrane regions while AtHMGR had three transmembrane regions. GuHMGR, AaHMGR, and AtHMGR all had the active
Xiao-Li, Zhang +5 more
openaire +1 more source
In this study, we used bioinformatic tools to analyze the 3-hydroxy-3-methylglutaryl-CoA reductase(HMGR) genes from Glycyrrhiza uralensis, Artemisia annua, and Arabidopsis thaliana. The results indicated that GuHMGR and AaHMGR contained two transmembrane regions while AtHMGR had three transmembrane regions. GuHMGR, AaHMGR, and AtHMGR all had the active
Xiao-Li, Zhang +5 more
openaire +1 more source