Results 101 to 110 of about 208,181 (247)
Granulomatous Panniculitis in a Patient Treated With Cemiplimab: Case Report and Literature Review
JEADV Clinical Practice, EarlyView.ABSTRACT Immune checkpoint inhibitors (ICIs) have become a cornerstone in the treatment of advanced malignancies by enhancing antitumor immunity, but they may also trigger a broad spectrum of immune‐related adverse events (irAEs) involving multiple organs.
B. Lada‐Colunga +6 more
wiley +1 more source
Uncovering Key Characteristics of Antibacterial Peptides through Machine Learning
Macromolecular Rapid Communications, EarlyView.Machine‐learning (ML) techniques using random forest classification models revealed key characteristics that predict effective antimicrobial peptides (AMPs) targeting Gram‐negative bacteria, Gram‐positive bacteria, and mycobacteria. The ideal cLogP (<$ < $−6) and net‐charge (≤+4) threshold was the same for all three targets with variations in the ...
Jooyoung Roh +2 more
wiley +1 more source
Quantifying Protein–Glycan Interactions Using Native Mass Spectrometry
Mass Spectrometry Reviews, EarlyView.ABSTRACT Interactions between glycan‐binding proteins (GBPs) and carbohydrates (glycans) are essential to many biological processes relevant to human health and disease. For most GBPs, however, their glycan interactome—the repertoire of glycans recognized and their specificities—is poorly defined.
Duong T. Bui +4 more
wiley +1 more source
Movement Disorders, EarlyView.Abstract Background Peripheral disease mechanisms such as immune dysregulation may contribute to Parkinson's disease (PD). To investigate interactions between common PD mutations and immune responses to environmental pathogens, we studied responses to Pseudomonas aeruginosa (P.
Julian R. Mark +8 more
wiley +1 more source
Medicinal Research Reviews, EarlyView.ABSTRACT Respiratory syncytial virus (RSV) is a common virus that causes respiratory infections, posing a serious threat, particularly to infants, the elderly, and individuals with compromised immune systems. As the leading cause of lower respiratory tract infections (LRTIs) in infants, RSV is responsible for millions of cases worldwide each year.
Jie Shi +6 more
wiley +1 more source
ATP burst is the dominant driver of antibiotic lethality in Mycobacterium smegmatis
eLifeAntibiotic-tolerant bacteria, due to their unique physiology, are refractory to antimicrobial killing and pose challenges for infection control. Incomplete knowledge of how bactericidal antibiotics work limits our understanding of partial resistance due ...
Tejan Lodhiya +5 more
doaj +1 more source
Mathematical Methods in the Applied Sciences, EarlyView.ABSTRACT In the present investigation, a mathematical model with vaccination, treatment, and environmental impact under real data is presented. Initially, we present the model without any interventions, followed by an examination of its equilibrium points.
Bashir Al‐Hdaibat +4 more
wiley +1 more source
Diagnosis and Management of Isolated Laryngeal Sarcoidosis: A Systematic Review
Otolaryngology–Head and Neck Surgery, EarlyView.Abstract Objective This study reviews the existing literature on patients diagnosed with sarcoidosis isolated to the larynx to improve our understanding of the diagnosis and management of this rare condition. Data Sources Embase, PubMed, Web of Science.
Raj Malhotra +5 more
wiley +1 more source
Persistent Facial Nodules in an Elderly Patient
JEADV Clinical Practice, EarlyView.
Qian Ding +2 more
wiley +1 more source
People and Nature, EarlyView.Abstract Understanding the frequency and socio‐ecological drivers of contacts between humans and non‐human primates (NHPs) is crucial for enhancing coexistence that favours NHP conservation, while limiting negative consequences such as aggressions and cross‐species disease transmission.
Cristina Caparrós‐Vallcorba +3 more
wiley +1 more source