Results 111 to 120 of about 648,089 (387)
Biosynthesis of mycobacterial arabinogalactan: identification of a novel (13)arabinofuranosyltransferase [PDF]
, 2008 The cell wall mycolyl-arabinogalactan-peptidoglycan complex is essential in mycobacterial species, such as Mycobacterium tuberculosis and is the target of several anti-tubercular drugs.
Alderwick, Luke J. +9 more
core +1 more source
Advanced Science, EarlyView.B‐OMVs, nanoscale vesicles derived from BCG, are identified as effective and safe inducers of trained immunity that protect against sepsis. Through TLR2‐mediated metabolic and epigenetic reprogramming of hematopoietic stem cells, B‐OMVs enhance inflammatory response and phagocytic activity.
Yuan Gong +16 more
wiley +1 more source
International Journal of Mycobacteriology, 2015 Representative strains of Mycobacterium avium, Mycobacterium intracellulare and Mycobacterium scrofulaceum (MAIS) grew at equal rates in laboratory medium at 21% (air) and 12% oxygen. Growth in 6% oxygen proceeded at a 1.4-1.8-fold lower rate. Colony formation was the same at 21% (air) and 6% oxygen.
Joseph O. Falkinham, Amy Herndon Lewis
openaire +4 more sources
Advanced Science, EarlyView.Naturally derived biomembrane nanostructures by mimicking evolutionarily optimized biological architectures could effectively suppress tumor growth and have emerged as a compelling strategy in translational biomedicine. This review provides a systematic overview of rational design and underlying antitumor therapeutic mechanisms of mammalian cells ...
Xiaodan Wei +10 more
wiley +1 more source
, 2006 POPULATION: Spinal cord injury (SCI) patients with neurogenic bladder have an increased risk for symptomatic urinary tract infection (UTI). Recurrent UTI requires multiple courses of antibiotic therapy, markedly increasing the incidence of multidrug ...
Bernard, Louis +6 more
core +1 more source
Plasticizer degradation by marine bacterial isolates : a proteogenomic and metabolomic characterization [PDF]
, 2020 Many commercial plasticizers are toxic endocrine-disrupting chemicals that are added to plastics during manufacturing and may leach out once they reach the environment.
Bosch, Rafael +3 more
core +3 more sources
The molecular clock of Mycobacterium tuberculosis
bioRxiv, 2019 The molecular clock and its phylogenetic applications to genomic data have changed how we study and understand one of the major human pathogens, Mycobacterium tuberculosis (MTB), the causal agent of tuberculosis.
Fabrizio Menardo +3 more
semanticscholar +1 more source
Diosgenin ameliorates silica‐induced tuberculosis in rats
Animal Models and Experimental Medicine, EarlyView.Silicosis increases susceptibility to tuberculosis due to impaired macrophage function and oxidative stress. This study demonstrates that diosgenin, a steroidal saponin, significantly inhibits Mycobacterium smegmatis (IC₅₀ = 0.006 μg/mL), reduces lung fibrosis, and restores antioxidant enzyme levels (↑SOD, ↑CAT, ↓MDA) in silica‐exposed rats ...
Williams Asamoah Adu +5 more
wiley +1 more source
A single regulator NrtR controls bacterial NAD+ homeostasis via its acetylation
eLife, 2019 Nicotinamide adenine dinucleotide (NAD+) is an indispensable cofactor in all domains of life, and its homeostasis must be regulated tightly. Here we report that a Nudix-related transcriptional factor, designated MsNrtR (MSMEG_3198), controls the de novo ...
Rongsui Gao +5 more
doaj +1 more source
Lipoproteins of Mycobacterium tuberculosis : an abundant and functionally diverse class of cell envelope components [PDF]
, 2004 Mycobacterium tuberculosis remains the predominant bacterial scourge of mankind. Understanding of its biology and pathogenicity has been greatly advanced by the determination of whole genome sequences for this organism.
Harrington, Dean, Sutcliffe, Iain
core +1 more source