Results 111 to 120 of about 541,488 (343)

Molecular epidemiology of Mycobacterium bovis in Cameroon [PDF]

open access: yes, 2017
We describe the largest molecular epidemiological study of Bovine Tuberculosis (bTB) in a sub-Saharan African country with higher spatial resolution providing new insights into bTB. Four hundred and ninety-nine samples were collected for culture from 201
Asuquo, A.   +13 more
core   +2 more sources

A case report of cutaneous infection with Mycobacterium neoaurum [PDF]

open access: gold, 2023
Alireza Mohebbipour‐Loren   +3 more
openalex   +1 more source

Population pharmacokinetics of TBAJ‐587 and its main metabolites—Evaluation of different loading dose strategies and early dose selection

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Background and Aim The rise of drug‐resistant tuberculosis (TB) poses a need for new drugs and combinations. TBAJ‐587, a new diarylquinoline (DARQ), has shown promising efficacy in preclinical studies. This work aimed to describe the pharmacokinetics (PK) of TBAJ‐587 and its metabolites M2 and M3 after single ascending dosing in healthy volunteers and ...
Albin A. M. Leding   +6 more
wiley   +1 more source

Evaluation of Genetic Pattern of Non-Tuberculosis Mycobacterium Using VNTR Method

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2011
Background and Objectives: Epidemiological studies of Non-tuberculosis Mycobacterium is important because of the drug resistance pattern and worldwide dissemination of these organisms.
F Heidari, P Farnia, J Noorozi, A Majd
doaj  

No difference in paratuberculosis seroprevalence between organic and conventional dairy herds in the Netherlands [PDF]

open access: yes, 2005
Purpose. Paratuberculosis or Johne’s disease in cattle is considered to play a role in the pathogenesis of Crohn’s disease in humans. Whether organic production may influence the prevalence of paratuberculosis in dairy herds was not known until now and ...
Kijlstra, Prof.Dr. A.
core   +10 more sources

Mycobacterial panniculitis caused by Mycobacterium thermoresistibile in a cat. [PDF]

open access: yes, 2016
Case summaryA domestic shorthair cat was evaluated for chronic, bilateral, ulcerative dermatitis affecting the inguinal region and lateral aspects of both pelvic limbs.
Keel, M Kevin   +3 more
core   +2 more sources

Pharmacokinetics of dolutegravir, tenofovir and lamivudine during venous–venous extracorporeal membrane oxygenation (VV‐ECMO): A case report

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
While providing potentially life‐saving cardiorespiratory support for critically ill patients, extracorporeal membrane oxygenation (ECMO) may detrimentally affect pharmacokinetic (PK) performance and concurrent drug efficacy and safety. We describe a patient with Pneumocystis jirovecii pneumonia (PJP) in the context of acquired immunodeficiency ...
Tom C. Zwart   +7 more
wiley   +1 more source

New and Improved Diagnostics for Detection of Drug-Resistant Pulmonary Tuberculosis. [PDF]

open access: yes, 2011
PURPOSE OF REVIEW: Tuberculosis (TB) remains a global emergency and continues to kill 1.7 million people globally each year. Drug-resistant TB is now well established throughout the world and most TB patients are not being screened for drug resistance ...
Affolabi   +41 more
core   +1 more source

Engineering of 2‐ketoacid Decarboxylases for Production of Isobutanol and Other Fusel Alcohols in Saccharomyces cerevisiae

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Isobutanol is a fusel alcohol that can be produced microbially for use as a biofuel or upgraded into sustainable aviation fuel (SAF). A key enzyme in the isobutanol biosynthetic pathway is 2‐ketoacid decarboxylase (KDC), which irreversibly decarboxylates 2‐ketoisovalerate (KIV) to yield isobutyraldehyde.
Joshua J. Dietrich   +6 more
wiley   +1 more source

Screening vaccine formulations for biological activity using fresh human whole blood. [PDF]

open access: yes, 2014
Understanding the relevant biological activity of any pharmaceutical formulation destined for human use is crucial. For vaccine-based formulations, activity must reflect the expected immune response, while for non-vaccine therapeutic agents, such as ...
Aboutorabian, Sepideh   +9 more
core   +1 more source

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