Cerebrospinal Fluid Metabolome in Central Nervous System Infections: A Study of Diagnostic Accuracy
Objective To assess the diagnostic accuracy of metabolites in cerebrospinal fluid (CSF) for central nervous system (CNS) infections. Methods Patients were derived from three prospective cohort studies in the Netherlands. All studies included adults suspected of a CNS infection who underwent a diagnostic lumbar puncture.
Steven L. Staal+7 more
wiley +1 more source
Deoxyribonucleic Acid Relatedness Among Selected Strains of Mycobacterium tuberculosis, Mycobacterium bovis, Mycobacterium bovis BCG, Mycobacterium microti, and Mycobacterium africanum [PDF]
Deoxyribonucleic acids (DNAs) of selected strains of the Mycobacterium tuberculosis complex, including strains of M. tuberculosis, Mycobacterium bovis, M. bovis BCG, Mycobacterium microti, and Mycobacterium africanum, were isolated and analyzed spectrophotometrically.
openaire +2 more sources
Photo‐controlled Release of Urea Enables the Detection of Urea‐Urease Intermediates by cryo‐FTIR
Caged compounds are a valuable tool to photocontrol the release of enzymatic substrates in a reaction. For example, caged urea molecules were proposed to control urea delivery to urease reactions and aid the determination of the catalytic mechanism of this enzyme.
Caterina Netto+7 more
wiley +1 more source
Abstract Analysis of triacylglycerol (TG) and phospholipid sn‐positional isomers can be divided into two main categories: (a) direct separation by chromatography or other means such as ion mobility mass spectrometry and (b) quantification of regioisomer ratios by structurally informative fragment ions with mass spectrometric methods.
Mikael Fabritius, Baoru Yang
wiley +1 more source
Relationship between Mycobacterium nonchromogenicum, Mycobacterium terrae, Mycobacterium novum and Subgroup “V” (Mycobacterium trivial) [PDF]
ABSTRACTComparison was made among Mycobacterium nonchromogenicum, M. terrae, M. novum and subgroup “V” (M. trivial) These organisms together are differentiated from other mycobacteria of group II and group III by the following characters: (1) Sensitiveness to ethambutol; (2) Tolerance to nitrite; (3) Tolerance to Tween 80; (4) Inability to utilize ...
openaire +3 more sources
Polyvinyl Alcohol‐Based Cryogels: Design, Characterization, and In Vitro Biological Studies
ABSTRACT Using inappropriate wound dressings makes the wound prone to bacteria invasion, impeding the wound‐healing process. In this work, cryogels were prepared from selected polymers, such as polyvinyl alcohol (PVA), hydroxypropylmethylcellulose (HPMC), and sodium alginate (SA) via a freeze–thaw method and loaded with Capparis sepiaria plant extract ...
Hlalisa Kula+10 more
wiley +1 more source
Noncoding RNAs in Host–Microbiota Interaction
The intricate interplay between gut microbiota and the host exerts a profound impact on host biological processes and disease development. This review highlights the pivotal role of noncoding RNAs (ncRNAs) in this interaction. Host ncRNAs regulate gene expression and microbiota composition, whereas microbial small RNAs (sRNAs) modulate host gene ...
Ziyi Zhao+7 more
wiley +1 more source
Confirmation of the presence of Mycobacterium-tuberculosis complex-specific DNA in three archaeological specimens [PDF]
This journal published the first reported identification of Mycobacterium tuberculosis complex (MTE) DNA in ancient human remains but CONCERNS were raised about the article two years after publication.
Donoghue, HD+4 more
core +1 more source
Gout and NLRP3 Inflammasome Biology
This review describes the three broad stages of acute inflammation in the context of gout: initiation, leucocyte mobilization, and self‐resolution. A typical case of a gout flare is presented. The role of the NLRP3 inflammasome in acute monosodium urate crystal–induced inflammation is reviewed in detail.
Raewyn Poulsen, Nicola Dalbeth
wiley +1 more source
Diagnóstico de meningitis tuberculosa
La tuberculosis continúa siendo un problema mundial de salud pública y su presentación como meningitis tuberculosa es grave, ya que ocasiona una gran parte de muertes y discapacidad.
Juan Sebastián Saavedra +3 more
doaj +1 more source