Results 151 to 160 of about 648,089 (387)

High Sensitivity L‐Cysteine Indium Telluriselenide Quantum Dot‐Inspired Aptasensor for Interferon Gamma TB Biomarker

ChemElectroChem, EarlyView.
An electrochemical interferon‐gamma (IFN‐γ) aptasensor is developed with L‐cysteine‐indium telluriselenide quantum dot (QD) and 24 mer guanine‐thymine DNA aptamer. The aptasensor exhibits high sensitivity in buffer and human serum samples. From calibration analysis, the limit of detection of the aptasensor is 0.312 pg mL−1 IFN‐γ, which indicates good ...
Kaylin Cleo Januarie, Usisipho Feleni, Candice Cupido, Nelia Abraham Sanga, Rachel Fanelwa Ajayi, Emmanuel Iheanyichukwu Iwuoha, Marlon Oranzie, Jaymi Leigh January, Zandile Dennis Leve   +8 more
wiley   +1 more source

Correlation between GenoType MTBDRplus Assay and Phenotypic Susceptibility Test for Prothionamide in Patients with Genotypic Isoniazid Resistance

Tuberculosis and Respiratory Diseases, 2019
Background The purpose of this study was to analyze the relationship between the gene mutation patterns by the GenoType MTBDRplus (MTBDRplus) assay and the phenotypic drug susceptibility test (pDST) results of isoniazid (INH) and prothionamide (Pto).
Joo Hee Lee, M.D., Kyung-Wook Jo, M.D., Ph.D., Tae Sun Shim, M.D., Ph.D.   +2 more
doaj  

Biologic Changes in Sulfonamide-resistant Mycobacterium ranae [PDF]

, 1946
Dirán Yegian, Vera Budd, Gardner Middlebrook   +2 more
openalex   +1 more source

Out-of-Africa migration and Neolithic co-expansion of Mycobacterium tuberculosis with modern humans

Nature Genetics, 2013
Tuberculosis caused 20% of all human deaths in the Western world between the seventeenth and nineteenth centuries and remains a cause of high mortality in developing countries. In analogy to other crowd diseases, the origin of human tuberculosis has been
Iñaki Comas, M. Coscollá, Tao Luo, S. Borrell, Kathryn E. Holt, M. Kato-Maeda, Julian Parkhill, Bijaya Malla, Stefan Berg, Guy Thwaites, D. Yeboah-Manu, G. Bothamley, Jian Mei, Lanhai Wei, S. Bentley, Simon R. Harris, Stefan Niemann, Roland Diel, Abraham Aseffa, Qian Gao, Douglas B. Young, S. Gagneux   +21 more
semanticscholar   +1 more source

Disruption of salt bridge interactions in the inter‐domain cleft of the tubulin‐like protein FtsZ of Escherichia coli makes cells sensitive to the cell division inhibitor PC190723

Cytoskeleton, EarlyView.
Abstract FtsZ forms a ring‐like assembly at the site of division in bacteria. It is the first protein involved in the formation of the divisome complex to split the cell into two halves, indicating its importance in bacterial cell division. FtsZ is an attractive target for developing new anti‐microbial drugs to overcome the challenges of antibiotic ...
Sakshi Mahesh Poddar, Joyeeta Chakraborty, Pananghat Gayathri, Ramanujam Srinivasan   +3 more
wiley   +1 more source

ANTAGONISM OF METHIONINE IN AMINOSALICYLATE-INHIBITION OF MYCOBACTERIUM TUBERCULOSIS [PDF]

, 1958
Loyd W. Hedgecock
openalex   +1 more source

Synthesis, Antimycobacterial Activity, and Computational Insight of Novel 1,4‐Benzoxazin‐2‐one Derivatives as Promising Candidates against Multidrug‐Resistant Mycobacterium Tuberculosis

ChemMedChem, EarlyView.
A series of 14 novel 1,4‐benzoxazinone derivatives is tested against various strains of Mycobacterium tuberculosis. All compounds show high activity against all tested strains, particularly the resistant strains. Additionally, the novel derivatives exhibit low cytotoxicity toward mammalian Vero cells.
Maria Grazia Mamolo, Emanuele Carosati, Diletta Pasin, Alessandro De Logu, Gianluigi Cabiddu, Marko Jukič, Daniele Zampieri   +6 more
wiley   +1 more source

Evaluation of Genetic Pattern of Non-Tuberculosis Mycobacterium Using VNTR Method

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2011
Background and Objectives: Epidemiological studies of Non-tuberculosis Mycobacterium is important because of the drug resistance pattern and worldwide dissemination of these organisms.
F Heidari, P Farnia, J Noorozi, A Majd
doaj  

Application of Transcriptomics to Enhance Early Diagnostics of Mycobacterial Infections, with an Emphasis on Mycobacterium avium ssp. paratuberculosis

Veterinary Sciences, 2019
Mycobacteria cause a wide variety of disease in human and animals. Species that infect ruminants include M. bovis and M. avium ssp. paratuberculosis (MAP). MAP is the causative agent of Johne’s disease in ruminants, which is a chronic granulomatous
Marielle H. van den Esker, Ad P. Koets
doaj   +1 more source

A Variant of Mycobacterium ranae Requiring Streptomycin for Growth [PDF]

, 1948
Dirán Yegian, Vera Budd
openalex   +1 more source