Results 161 to 170 of about 648,089 (387)

Molecular biology techniques as a tool for detection and characterisation of Mycobacterium avium subsp. paratuberculosis [PDF]

open access: yes, 2002
Mycobacterium avium subsp. paratuberculosis (M. paratuberculosis) is the causative agent of paratuberculosis, also known as Johne’s disease, a chronic intestinal infection in cattle and other ruminants.
Englund, Stina
core  

Mycobacterium abscessus Complex Infections in Humans

open access: yesEmerging Infectious Diseases, 2015
New treatments, rapid and inexpensive identification methods, and measures to contain nosocomial transmission and outbreaks are urgently needed.
Meng-Rui Lee   +5 more
semanticscholar   +1 more source

Intracellular and Extracellular Efficacy of Homoisoflavone Derivatives Against Mycobacterium Tuberculosis: Progress Toward Novel Antitubercular Agents

open access: yesChemMedChem, EarlyView.
A series of 42 homoisoflavones were synthesized and evaluated against Mycobacterium tuberculosis (Mtb). Three derivatives showed potent inhibition of Mtb strains. Evaluation in infected macrophages revealed promising intracellular activity, where one derivative featuring a nitrofuranyl and piperidine group emerges as the most promising.
Sanderson D. Calixto   +12 more
wiley   +1 more source

Mycobacterium tuberculosis - the 10 years of epidemiological and diagnostics studies [PDF]

open access: yes, 2005
Tuberculosis (ТВ) is the main bacterial pathogen that causes more deaths than AIDS, malaria and all infectious diseases. The unusual long doubling time (about 24h), highly hydrophobic cell envelope resistant to chemical lysis was the reason to delay ...
Boruń-Popławska, Marta   +3 more
core  

Limitations of variable number of tandem repeat typing identified through whole genome sequencing of Mycobacterium avium subsp. paratuberculosis on a national and herd level [PDF]

open access: yes, 2015
Background: Mycobacterium avium subsp. paratuberculosis (MAP), the causative bacterium of Johne’s disease in dairy cattle, is widespread in the Canadian dairy industry and has significant economic and animal welfare implications. An understanding of the
Ahlstrom, Christina   +13 more
core   +1 more source

The distinct fate of smooth and rough Mycobacterium abscessus variants inside macrophages

open access: yesOpen Biology, 2016
Mycobacterium abscessus is a pathogenic, rapidly growing mycobacterium responsible for pulmonary and cutaneous infections in immunocompetent patients and in patients with Mendelian disorders, such as cystic fibrosis (CF). Mycobacterium abscessus is known
A. Roux   +15 more
semanticscholar   +1 more source

Synthesis of Bioorthogonal Mycolic Acids: Chemoselective Reduction of β‐Ketoesters Containing an Alkyne Using the Noyori Catalyst

open access: yesEuropean Journal of Organic Chemistry, Accepted Article.
The asymmetric reduction of β‐ketoesters using the Noyori catalyst is a highly effective synthetic methodology, offering excellent stereocontrol for the preparation of enantiopure b‐hydroxyesters from prochiral substrates in high yields. This reaction has been used in the total synthesis of mycolic acids, which are α‐alkyl, β‐hydroxy fatty acids ...
Paulin Rollando   +5 more
wiley   +1 more source

Prolonged Outbreak of Mycobacterium chimaera Infection After Open-Chest Heart Surgery.

open access: yesClinical Infectious Diseases, 2015
BACKGROUND Invasive Mycobacterium chimaera infections were diagnosed in 2012 in 2 heart surgery patients on extracorporeal circulation. We launched an outbreak investigation to identify the source and extent of the potential outbreak and to implement ...
H. Sax   +10 more
semanticscholar   +1 more source

Associations between the gut microbiota, immune cells, and different subtypes of epilepsy: A Mendelian randomization study

open access: yesEpilepsia Open, EarlyView.
Abstract Objective The gut microbiota (GM) plays a role in epilepsy development via the microbiota–gut–brain axis. However, its relationship with various epilepsy subtypes and its mediating role through immune cells remain unclear. Thus, identifying the GM linked to specific epilepsy subtypes and investigating immune mechanisms to predict epilepsy risk,
Xu Zhang   +4 more
wiley   +1 more source

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