Results 41 to 50 of about 106,966 (124)

Label-free optical vibrational spectroscopy to detect the metabolic state of M. tuberculosis cells at the site of disease [PDF]

open access: yes, 2017
Tuberculosis relapse is a barrier to shorter treatment. It is thought that lipid rich cells, phenotypically resistant to antibiotics, may play a major role. Most studies investigating relapse use sputum samples although tissue bacteria may play an important role. We developed a non-destructive, label-free technique combining wavelength modulated Raman (
arxiv   +1 more source

Screening and Drug Resistance Analysis of Non-Tuberculous Mycobacteria in Patients with Suspected Pulmonary Tuberculosis on the Hainan Island, China

open access: yesInfection and Drug Resistance, 2023
Jieying Wang,* Zhuoling Chen,* Yuni Xu, Wenhua Qiu, Shaowen Chen, Hua Pei, Yeteng Zhong Department of Clinical Laboratory, The Second Affiliated Hospital Hainan Medical University, Haikou, People’s Republic of China*These authors contributed ...
Wang J   +6 more
doaj  

Modelling Bovine Granuloma Formation In Vitro upon Infection with Mycobacterium Avium Subspecies Paratuberculosis

open access: yesVeterinary Sciences, 2019
Mycobacterium avium subspecies paratuberculosis (Map) causes chronic granulomatous disease in cattle and ruminant livestock, causing substantial economic losses.
J. Hunter Rice   +3 more
doaj   +1 more source

Trends and Species Diversity of Non-tuberculous Mycobacteria Isolated From Respiratory Samples in Northern China, 2014–2021

open access: yesFrontiers in Public Health, 2022
BackgroundPulmonary non-tuberculous mycobacteria (NTM) infection has become a public health concern in China and around the world. The objective of this study was to describe the longitudinal changes in the frequency and diversity of NTM in northern ...
Qing Sun   +10 more
doaj   +1 more source

On the ability to reconstruct ancestral genomes from Mycobacterium genus [PDF]

open access: yesarXiv, 2017
Technical signs of progress during the last decades has led to a situation in which the accumulation of genome sequence data is increasingly fast and cheap. The huge amount of molecular data available nowadays can help addressing new and essential questions in Evolution.
arxiv  

Using Capsule Neural Network to predict Tuberculosis in lens-free microscopic images [PDF]

open access: yesarXiv, 2020
Tuberculosis, caused by a bacteria called Mycobacterium tuberculosis, is one of the most serious public health problems worldwide. This work seeks to facilitate and automate the prediction of tuberculosis by the MODS method and using lens-free microscopy, which is easy to use by untrained personnel.
arxiv  

A single regulator NrtR controls bacterial NAD+ homeostasis via its acetylation

open access: yeseLife, 2019
Nicotinamide adenine dinucleotide (NAD+) is an indispensable cofactor in all domains of life, and its homeostasis must be regulated tightly. Here we report that a Nudix-related transcriptional factor, designated MsNrtR (MSMEG_3198), controls the de novo ...
Rongsui Gao   +5 more
doaj   +1 more source

Analysis of DevR regulated genes in Mycobacterium tuberculosis [PDF]

open access: yesarXiv, 2013
The DevRS two component system of Mycobacterium tuberculosis is responsible for its dormancy in host and becomes operative under hypoxic condition. It is experimentally known that phosphorylated DevR controls the expression of several downstream genes in a complex manner.
arxiv  

Elusive preferred hosts or nucleic acid level selection? A commentary on: Evolutionary interpretations of mycobacteriophage biodiversity and host-range through the analysis of codon usage bias (Esposito et al. 2016) [PDF]

open access: yesarXiv, 2016
While confirming the long held view that viruses do not closely imitate the use of their host's codon catalogue, Esposito and coworkers nevertheless consider it surprising that, despite having the ability to infect the same host, many mycobacteriophages share little or no genetic similarity (i.e.
arxiv  

Construction and Use of Transposon MycoTetOP2 for Isolation of Conditional Mycobacteria Mutants

open access: yesFrontiers in Microbiology, 2020
Mycobacteria are unique in many aspects of their biology. The development of genetic tools to identify genes critical for their growth by forward genetic analysis holds great promises to advance our understanding of their cellular, physiological and ...
Sarah D. Riggs-Shute   +3 more
doaj   +1 more source

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