Results 111 to 120 of about 76,910 (294)

Atg5 regulates formation of MyD88 condensed structures and MyD88-dependent signal transduction. [PDF]

application/pdfMyD88 is known as an essential adaptor protein for Toll-like receptors (TLRs). Previous studies have shown that transfected MyD88 forms condensed structures in the cytoplasm.
1778, Murakami, Yukitaka, 9000258692374, Niida, Shumpei, INOMATA, MEGUMI, INTO, TAKESHI, 3933, 3934, 1779   +8 more
core   +1 more source

MyD88 Intrinsically Regulates CD4 T-Cell Responses

, 2009
Myeloid differentiation factor 88 (MyD88) is an essential adaptor protein in the Toll-like receptor-mediated innate signaling pathway, as well as in interleukin-1 receptor (IL-1R) and IL-18R signaling.
Bronson, R T, Robert W. Finberg, Chan, M, Anna M. Cerny, Chan, Melvin, Roderick Terry Bronson, Bronson, Roderick T., Finberg, R W, Finberg, Robert W., Zhou, S, Kurt, Jones E, Cerny, Anna M., Shenghua Zhou, Melvin Chan, Evelyn A. Kurt-Jones, Zhou, Shenghua, Kurt-Jones, Evelyn A., Cerny, A M   +17 more
core   +2 more sources

Myeloid Differentiation Primary Response Protein 88: An Important Therapeutic Target for Chronic Pain

Journal of Pain Research
Hanlin Liang,1 Linbin Fu,1 Zheng Li,1,2,* Zhiheng Liu1,* 1Department of Anesthesiology, The First Affiliated Hospital of Shenzhen University, Shenzhen Second People’s Hospital, Shenzhen, People’s Republic of China; 2Department of Anesthesiology ...
Liang H, Fu L, Li Z, Liu Z
doaj  

Eudragit®‐engineered pH‐responsive probiotic microspheres with enhanced gastrointestinal resistance and prolonged storage stability for inflammatory bowel disease therapy

BMEMat, EarlyView.
This study reports the development of AMS@Eud core‐shell microspheres, combining calcium alginate and pH‐responsive Eudragit® L100, which exhibit exceptional gastrointestinal resistance and long‐term storage stability (only 5.28%–9.09% viability loss over 35 days at 4–25°C), and effectively alleviate inflammatory bowel disease via gut microbiota ...
Ming Teng, Xiaomin Luo, Peng Zhang, Chen Yang, Yuniel Ma, Xinhua Liu   +5 more
wiley   +1 more source

The Salmonella pathogenicity island (SPI)-2 and SPI-1 type III secretion systems allow Salmonella serovar typhimurium to trigger colitis via MyD88-dependent and MyD88-independent mechanisms.

, 2005
Salmonella typhimurium can colonize the gut, invade intestinal tissues, and cause enterocolitis. In vitro studies suggest different mechanisms leading to mucosal inflammation, including 1) direct modulation of proinflammatory signaling by bacterial type ...
Stecher, Bärbel, Barthel, Manja, Stallmach, Thomas, Hensel, Michael, Hapfelmeier, Siegfried, Müller, Andreas J, Heikenwalder, Mathias, Kremer, Marcus, Pfeffer, Klaus, Akira, Shizuo, Hardt, Wolf-Dietrich   +10 more
core  

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source

Cell-type specific MyD88 signaling is required for intestinal tumor initiation and progression to malignancy

OncoImmunology, 2018
The signal adapter MyD88, an essential component of Toll-like receptor (TLR) signaling, is important for gut-microbiome interactions. However, its contribution to cancer and its cell-type specific functions are controversially discussed.
Anne Holtorf, Anja Conrad, Bernhard Holzmann, Klaus-Peter Janssen   +3 more
doaj   +1 more source

Atomically precise metal cluster enzymes for pathological tissue regeneration

BMEMat, EarlyView.
Schematic illustration of atomically precise metal cluster enzymes (MCEs) for pathological tissue regeneration. Atomically precise MCEs can modulate biological processes, such as attenuation of inflammatory responses, eradication of bacterial pathogens, regulation of angiogenesis, and promotion of cell development.
Ziqiang Xiong, Zhifeng Shi, Mengqing Li, Jien Han, Haoyan Chen, Maofei Ran, Shaojian Zhong, Limin Ma, Chengyun Ning, Youzhun Fan, Zhenghua Tang, Peng Yu   +11 more
wiley   +1 more source

Prognostic significance of MyD88 expression by human epithelial ovarian carcinoma cells

Journal of Translational Medicine, 2012
Background MyD88 is an adaptor protein for TLR-4 signaling known to mediate paclitaxel resistance in epithelial ovarian carcinoma (EOC). This study examined the clinical significance of MyD88 expression in EOC.
Zhu Yi, Huang Jian-Ming, Zhang Guo-Nan, Zha Xiao, Deng Bi-Fang   +4 more
doaj   +1 more source

MYD88 Mutations and Sensitivity to Ibrutinib Therapy [PDF]

The Journal of Molecular Diagnostics, 2018
This Correspondence relates to the article by Bobee et al (Determination of Molecular Subtypes of Diffuse Large B-Cell Lymphoma Using a Reverse Transcriptase Multiplex Ligation-Dependent Probe Amplification Classifier: A CALYM Study. J Mol Diagn 2017,19:892-904).
openaire   +2 more sources