Results 121 to 130 of about 85,956 (299)
Prognostic significance of MyD88 expression by human epithelial ovarian carcinoma cells
Journal of Translational Medicine, 2012 Background MyD88 is an adaptor protein for TLR-4 signaling known to mediate paclitaxel resistance in epithelial ovarian carcinoma (EOC). This study examined the clinical significance of MyD88 expression in EOC.
Zhu Yi +4 more
doaj +1 more source
International Journal of Molecular Medicine, 2019 The role of myeloid differentiation factor 88 (MyD88) in malignant tumors is largely unknown. Therefore, in this study, we aimed to examine the function and underlying mechanism of MyD88 in colorectal carcinoma in vitro using SW480 and HCT116 cell lines ...
Guang-Wei Zhu +6 more
semanticscholar +1 more source
MYD88 Mutations and Sensitivity to Ibrutinib Therapy [PDF]
The Journal of Molecular Diagnostics, 2018 This Correspondence relates to the article by Bobee et al (Determination of Molecular Subtypes of Diffuse Large B-Cell Lymphoma Using a Reverse Transcriptase Multiplex Ligation-Dependent Probe Amplification Classifier: A CALYM Study. J Mol Diagn 2017,19:892-904).
openaire +2 more sources
Journal of Periodontology, EarlyView.Abstract Background Periodontitis has been associated with other systemic inflammatory diseases, such as cardiovascular disease, diabetes mellitus, and rheumatoid arthritis; through the translocation of oral bacteria and local inflammatory mediators systemically.
Hadeel Mohammed Abbood +3 more
wiley +1 more source
Spatiotemporal expression of MYD88 gene in pigs from birth to adulthood
Genetics and Molecular Biology, 2018 MYD88 plays an important role in the immune response against infections. To analyze MYD88 gene expression during different stages of pig development, we used real-time PCR. MYD88 was seen expressed in all tissues examined.
LiNa Gan +4 more
doaj +1 more source
Haematologica, 2019 More than 50 subtypes of B-cell non-Hodgkin lymphoma (B-NHL) are recognized in the most recent World Health Organization classification of 2016. The current treatment paradigm, however, is largely based on ‘one-size-fits-all’ immune-chemotherapy ...
R. D. de Groen +4 more
semanticscholar +1 more source
Real World Use of the IL‐36 Receptor Antagonist Spesolimab: A Systematic Review and Analysis
JEADV Clinical Practice, EarlyView.ABSTRACT Background Spesolimab, an interleukin‐36 receptor antagonist, is approved for the treatment and prevention of generalised pustular psoriasis (GPP) flares. Its use has increasingly been reported in real‐world settings for both GPP and other inflammatory dermatoses.
Sophia A. Mense +4 more
wiley +1 more source
Gastroenterology Research and Practice, 2011 Liver regeneration is known to occur in mice lacking one or more Toll-like receptors (TLRs) or the adaptor protein MyD88. Though MyD88 is required for signaling by many TLRs, others signal via MyD88-independent pathways, leading to the induction of type ...
Javier Vaquero +3 more
doaj +1 more source
Molecular Carcinogenesis, EarlyView.ABSTRACT Neutrophil extracellular traps (NETs) and inflammatory mediators have been implicated in head and neck squamous cell carcinoma, but their relationship with systemic inflammatory status during radiotherapy remains incompletely understood. This exploratory integrative study combined a literature‐guided network‐based bioinformatic prioritization ...
Eloa Mangabeira Santos +11 more
wiley +1 more source
Med Research, EarlyView.This review systematically compares the size‐dependent toxicity of microplastics and nanoplastics in the intestine, liver, kidney, lung, and brain. Particle size determines bioavailability, barrier penetration, and injury mechanisms. Because of their small size and high surface reactivity, NPs readily cross the intestinal epithelium and blood–brain ...
Yixian Cheng +14 more
wiley +1 more source