Results 131 to 140 of about 8,110,219 (215)

Paramagnetic Rim Lesions Are Associated With Trans‐Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, Volume 13, Issue 9, Page 1831-1841, September 2026.
ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem   +17 more
wiley   +1 more source

Editorial: Myelin-Mediated Inhibition of Axonal Regeneration: Past, Present, and Future

open access: yesFrontiers in Molecular Neuroscience, 2017
Wilfredo Mellado, Sari Hannila
doaj   +1 more source

Proinflammatory Epstein–Barr Virus Antibody Functions Track with Disease Activity in Multiple Sclerosis

open access: yesAnnals of Neurology, Volume 100, Issue 3, Page 547-558, September 2026.
Objective Epstein–Barr virus (EBV) has been implicated in the pathogenesis of multiple sclerosis (MS). Elevated immunoglobulin G (IgG) titers against EBV nuclear antigen 1 (EBNA1) represent the most consistent serological marker of MS risk, with levels remaining persistently elevated following disease onset.
Malina Behrens   +9 more
wiley   +1 more source

A Phase Ib Case Series Using Bortezomib With Chemotherapy in Atypical Teratoid/Rhabdoid Tumors

open access: yesCancer Medicine, Volume 15, Issue 9, September 2026.
ABSTRACT Background Atypical teratoid/rhabdoid tumors (ATRTs) are aggressive pediatric brain tumors that are sensitive to proteasome inhibitors in preclinical models. We evaluated the feasibility of combining the proteasome inhibitor, bortezomib, with chemotherapy.
Wan‐Ling Ho   +38 more
wiley   +1 more source

Myelin oligodendrocyte glycoprotein associated disease

open access: yesJournal of Clinical Ophthalmology and Research
Nikhat Iqbal Tamboli   +3 more
doaj   +1 more source

Persistent Post‐Traumatic Brain Injury Hiccups Unresponsive to Standard Agents: Resolution Associated With Levetiracetam Therapy

open access: yesClinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Post‐traumatic hiccups are an uncommon but distressing complication of traumatic brain injury (TBI), often resistant to conventional pharmacological agents, and the underlying mechanism may involve central neurological disruption of inhibitory pathways rather than gastrointestinal or metabolic aetiologies. We report a male patient in his early
Rostom Karajeh   +4 more
wiley   +1 more source

Anaesthetic concerns in pregnancy associated with myelin oligodendrocyte glycoprotein encephalomyelitis

open access: yesIndian Journal of Anaesthesia, 2022
Aswini Kuberan   +3 more
doaj   +1 more source

Anti‐TNF‐Alpha Associated Central Nervous System Demyelination. Drug‐Induced Demyelination or Multiple Sclerosis Trigger? A Case Series

open access: yesClinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Adalimumab is a monoclonal antibody that targets TNF‐α and is effective in treating several autoimmune disorders, including non‐infectious uveitis; however, it has been associated with demyelinating lesions. This study presents two cases of CNS demyelination in patients who consumed adalimumab. First, an 18‐year‐old man presented with subacute
Marzie Abutorabi‐zarchi   +2 more
wiley   +1 more source

Recent Advancements in Drug Delivery Across the Blood–Brain Barrier in Amyotrophic Lateral Sclerosis (ALS)

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
Progressive BBB/BSCB dysfunction is increasingly recognized as both a pathological feature and a therapeutic barrier in ALS. Novel delivery technologies and barrier‐restoration strategies may enhance CNS drug exposure, improve the efficacy of disease‐modifying therapies, and advance ALS treatment. ABSTRACT Background Amyotrophic lateral sclerosis (ALS)
Nitesh Sanghai   +9 more
wiley   +1 more source

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