Results 151 to 160 of about 8,110,219 (215)
THE ROLE OF INFLAMMASOMES IN NEUROMYELITIS OPTICA SPECTRUM DISORDER (NMOSD) AND MYELIN OLIGODENDROCYTE GLYCOPROTEIN ANTIBODY-ASSOCIATED DISEASE (MOGAD) The Role of Inflammasomes in Neuromyelitis Optica Spectrum Disorder (NMOSD) and Myelin ...
Alabdullah, Moataz
core
ABSTRACT Background Glatiramer acetate is an injectable disease‐modifying therapy indicated for multiple sclerosis (MS). Aim To evaluate the real‐world safety and effectiveness of glatiramer acetate for MS in Japan. Methods A prospective, multicenter, observational, all‐case post‐marketing survey was conducted in Japan between November 2015 and March ...
Masaaki Niino +3 more
wiley +1 more source
ECM, extracellular matrix; BDNF, brain‐derived neuroptrophic factor; FGF, fibroblast growth factor; VEGF, vascular endothelial growth factor. Abstract Heparan sulfate, a structurally diverse glycosaminoglycan that is abundant in the central nervous system (CNS), orchestrates essential processes fundamental to neural plasticity, neurorepair, and ...
Mozammel H. Bhuiyan +3 more
wiley +1 more source
Attenuation of DOX‐Associated Biochemical and Histological Brain Alterations
This research highlights the need for practical methods to lessen the neurotoxicity caused by doxorubicin. ABSTRACT Background Doxorubicin (DOX) is a common anticancer drug used to treat various types of neoplasms. However, its use is associated with neurotoxic effects, including neuronal degeneration and damage.
Ehab Y. Abdelhiee +11 more
wiley +1 more source
This study provides the first comprehensive macroanatomical, histological, histochemical and scanning electron microscopic characterisation of the kidney in the Aksaray Malaklı dog. Key findings include normal canine renal architecture, absence of acidic polysaccharides, PAS‐positive basement membranes, and a previously unreported breed‐specific ...
Hatice Yaren Kuloğlu +3 more
wiley +1 more source
In this 28‐patient retrospective cohort, rituximab‐based regimens for IgM‐related neuropathy yielded significant, sustained functional and neurological improvements over a 2‐year follow‐up. Furthermore, reductions in serum IgM levels correlated with improved Inflammatory Neuropathy Cause and Treatment disability scores, highlighting the long‐term ...
Maria Gavriatopoulou +15 more
wiley +1 more source
New perspectives on VEGF signalling in Alzheimer's disease
Emery et al. bring together findings from recent multi‐omic studies, including single‐cell mRNA analysis of human post‐mortem brain tissue, and proteomic analysis of matched CSF and blood samples in large clinical studies. The authors present evidence of the involvement of altered VEGF signalling in vascular and immune dysfunction and neurodegeneration
Cherelle E. G. Emery +2 more
wiley +1 more source
ABSTRACT The peripheral nervous system (PNS) is responsible for innervating all regions of the body outside of the central nervous system (CNS), the latter consisting of the brain, spinal cord, and optic nerves. While myelin is an essential component for the efficient functioning of both CNS and peripheral nerve cells, it is particularly important for ...
Kathleen Margaret Hagen +1 more
wiley +1 more source
Renally Generated Ammonia as a Cause of Hyperammonaemic Non‐Hepatic Encephalopathy
ABSTRACT Encephalopathy with high ammonia levels is most commonly associated with cirrhosis or urea cycle disorders, but it can also result from renal ammoniagenesis when renal excretion of ammonium is impaired. In the literature, this has been shown to occur in the presence of (1) urinary diversion to a segment of intestine; (2) urea‐splitting ...
Victoria E. Nkunu +6 more
wiley +1 more source

