Results 171 to 180 of about 8,110,219 (215)

ANOMALIES OF MYELIN‐ASSOCIATED GLYCOPROTEINS IN‘QUAKING MICE

Journal of Neurochemistry, 1974
Abstract— Proteins and glycoproteins in a myelin fraction isolated from Quaking mutant mice were separated by polyacrylamide gel electrophoresis in the presence of sodium dodecyl sulphate and stained with Fast Green or with periodic acid‐Schiff reagents.
J M, Matthieu, R O, Brady, R H, Quarles
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Phosphorylation of Myelin-Associated Glycoprotein in Cultured Oligodendrocytes

Developmental Neuroscience, 1992
The myelin-associated glycoprotein (MAG) in primary cultures of oligodendrocytes is subject to phosphorylation in the absence of neurons. The positive response of this phosphorylation to vanadate suggests that one of the modified sites in MAG is phosphotyrosine.
L L, Bambrick, P E, Braun
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Preparation and characterization of antisera to the myelin-associated glycoprotein

Neurochemical Research, 1981
Rabbits were immunized with the myelin-associated glycoprotein (MAG) that had been purified from isolated rat brain myelin by selective extraction with lithium diiodosalicylate (LIS) and phenol followed by preparative SDS gel electrophoresis. Antibodies to MAG were detected qualitatively by immunodiffusion and quantitatively by a double antibody assay ...
R H, Quarles, D, Johnson, R O, Brady, N H, Sternberger   +3 more
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Structure of mouse myelin-associated glycoprotein gene

Biochemical and Biophysical Research Communications, 1991
The mouse myelin-associated glycoprotein gene was isolated from a mouse gene library. This gene was split into 13 exons distributed about 15 kb in length. Each extracellular immunoglobulin-related domain was encoded by a single exon, and RNA splicing between those exons occurred between the first and second nucleotides of the junctional codon, the ...
R, Nakano, N, Fujita, S, Sato, T, Inuzuka, K, Sakimura, H, Ishiguro, M, Mishina, T, Miyatake   +7 more
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Myelin-Associated Glycoprotein in Development and Disease

Developmental Neuroscience, 2009
The myelin-associated glycoprotein (MAG) is a 100 K-dalton, integral membrane glycoprotein containing 30% carbohydrate that is in central and peripheral myelin sheaths. Recent research on its function during normal myelinogenesis and possible roles in the pathology of demyelinating diseases is reviewed.
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Myelin-associated glycoprotein in the developing human retina

Experimental Eye Research, 1986
The immunohistochemical presence of myelin-associated glycoprotein (MAG) in Müller cells of the developing human retina was examined with rat monoclonal antibodies to MAG and the peroxidase antiperoxidase (PAP) method of Sternberger. Retinas of various developmental stages ranging between 9-31 gestational weeks were stained.
M L, Molnàr, M, Röytta, K, Stefansson, T A, Salmi, G K, Molnàr   +4 more
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Structural Properties of the Myelin‐Associated Glycoprotein Ectodomain

Journal of Neurochemistry, 1993
Abstract: Myelin‐associated glycoprotein (MAG) has been proposed to mediate adhesive interactions during myelin development. We have used the baculovirus expression system to produce a truncated form of this molecule [soluble extracellular domain of MAG (sMAG)] consisting of the complete extracellular ectodomain.
J, Attia, L, Hicks, K, Oikawa, C M, Kay, R J, Dunn   +4 more
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Molecular cloning of human myelin‐associated glycoprotein

Journal of Neuroscience Research, 1989
AbstractThe nucleotide sequence for human myelin‐associated glycoprotein (MAG) and its deduced amino acid sequence, obtained by analysis of two overlapping cDNA clones isolated from a human brain cDNA library, is presented and compared to that reported for rat MAG.The sequence provides an open reading frame of 1,878 nucleotides encoding a peptide of ...
G, Spagnol, M, Williams, J, Srinivasan, J, Golier, D, Bauer, R V, Lebo, N, Latov   +6 more
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Developmental and pathophysiological aspects of the myelin-associated glycoprotein

Cellular and Molecular Neurobiology, 1988
1. A glycoslylated sulfate-containing protein known as myelin-associated glycoprotein (MAG) appears to be unique to the central and peripheral nervous systems. This component has been characterized and cDNA clones have been isolated. 2. MAG is a member of the immunoglobulin superfamily.
R O, Brady, R H, Quarles
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Differential intracellular sorting of the myelin-associated glycoprotein isoforms

Journal of Neuroscience Research, 1996
Myelin-associated glycoprotein (MAG), a myelin-specific protein, is expressed as two isoforms, designated as L-MAG and S-MAG. Both share identical extracellular and transmembrane domains but differ in their cytoplasmic domains. L-MAG is expressed earlier during myelination than S-MAG.
J, Minuk, P E, Braun
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