Results 51 to 60 of about 294,817 (379)

T Cells Actively Infiltrate the White Matter of the Aging Monkey Brain in Relation to Increased Microglial Reactivity and Cognitive Decline

open access: yesFrontiers in Immunology, 2021
Normal aging is characterized by declines in processing speed, learning, memory, and executive function even in the absence of neurodegenerative diseases such as Alzheimer's Disease (AD). In normal aging monkeys and humans, neuronal loss does not account
Katelyn V. Batterman   +6 more
doaj   +1 more source

AxonDeepSeg: automatic axon and myelin segmentation from microscopy data using convolutional neural networks [PDF]

open access: yes, 2017
Segmentation of axon and myelin from microscopy images of the nervous system provides useful quantitative information about the tissue microstructure, such as axon density and myelin thickness. This could be used for instance to document cell morphometry
Antonsanti, Pierre-Louis   +5 more
core   +3 more sources

Astrocytes and Microglia as Major Players of Myelin Production in Normal and Pathological Conditions

open access: yesFrontiers in Cellular Neuroscience, 2020
Myelination is an essential process that consists of the ensheathment of axons by myelin. In the central nervous system (CNS), myelin is synthesized by oligodendrocytes. The proliferation, migration, and differentiation of oligodendrocyte precursor cells
E. Traiffort   +3 more
semanticscholar   +1 more source

A Novel Lysolecithin Model for Visualizing Damage in vivo in the Larval Zebrafish Spinal Cord

open access: yesFrontiers in Cell and Developmental Biology, 2021
Background: Lysolecithin is commonly used to induce demyelinating lesions in the spinal cord and corpus callosum of mammalian models. Although these models and clinical patient samples are used to study neurodegenerative diseases, such as multiple ...
Angela D. Morris   +2 more
doaj   +1 more source

Polyphosphoinositides in myelin [PDF]

open access: yesBiochemical Journal, 1965
1. On fractionation of guinea-pig forebrain homogenates by differential and gradient-density centrifugation most of the polyphosphoinositides were recovered in the myelin-rich particles. 2. The phospholipids of pure preparations of myelin contained di- and tri-phosphoinositide in proportions 2-3 times greater than in the whole-brain phospholipids.
R. M. C. Dawson, Joseph Eichberg
openaire   +3 more sources

Pathological Insights From Quantitative Susceptibility Mapping and Diffusion Tensor Imaging in Ice Hockey Players Pre and Post-concussion

open access: yesFrontiers in Neurology, 2018
Myelin sensitive MRI techniques, such as diffusion tensor imaging and myelin water imaging, have previously been used to reveal changes in myelin after sports-related concussions.
Alexander M. Weber   +14 more
doaj   +1 more source

A Physical Perspective to the Inductive Function of Myelin—A Missing Piece of Neuroscience

open access: yesFrontiers in Neural Circuits, 2021
Starting from the inductance in neurons, two physical origins are discussed, which are the coil inductance of myelin and the piezoelectric effect of the cell membrane.
Hao Wang   +7 more
doaj   +1 more source

Preliminary Evidence of Increased Hippocampal Myelin Content in Veterans with Posttraumatic Stress Disorder. [PDF]

open access: yes, 2015
Recent findings suggest the formation of myelin in the central nervous system by oligodendrocytes is a continuous process that can be modified with experience.
Chao, Linda L   +4 more
core   +1 more source

CD36-mediated uptake of myelin debris by macrophages and microglia reduces neuroinflammation

open access: yesJournal of Neuroinflammation, 2020
Background The presence of foamy macrophages and microglia containing intracellular myelin remnants is a pathological hallmark of neurodegenerative disorders such as multiple sclerosis (MS).
Elien Grajchen   +11 more
semanticscholar   +1 more source

Myelin figures: the buckling and flow of wet soap

open access: yes, 2009
Myelin figures are interfacial structures formed when certain surfactants swell in excess water. Here, I present data and model calculations suggesting myelin formation and growth is due to the fluid flow of surfactant, driven by the hydration gradient ...
A. M. Figueiredo Neto   +3 more
core   +1 more source

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