Results 31 to 40 of about 170,216 (297)

Synthesis of antagonists of Myelin-associated glycoprotein (MAG) for conformational and SAR studies [PDF]

, 2004
Damage to the central nervous system (CNS) of higher vertebrates, including humans, often results in devastating and persistent functional deficits.
Gao, Gan-Pan
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Data from: Assessment of dysmyelination with RAFFn MRI: application to murine MPS I

, 2021
Type I mucopolysaccharidosis (MPS I) is an autosomal recessive lysosomal storage disorder with neurological features. Humans and laboratory animals with MPS I exhibit various white matter abnormalities involving the corpus callosum and other regions.
Idiyatullin, Djaudat,University of Minnesota, Michaeli, Shalom,University of Minnesota, Satzer, David,University of Minnesota, Liimatainen, Timo,University of Eastern Finland, Parr, Ann M.,University of Minnesota, Ritchie, Michael M.,University of Minnesota, Storino, Christine,University of Minnesota, Low, Walter C.,University of Minnesota, Hakkarainen, Hanne,University of Eastern Finland, DiBartolomeo, Christina,University of Minnesota, Mangia, Silvia,University of Minnesota   +10 more
core   +2 more sources

Time-lapse imaging of the dynamics of CNS glial-axonal interactions in vitro and ex vivo [PDF]

, 2012
<b>Background</b> Myelination is an exquisite and dynamic example of heterologous cell-cell interaction, which consists of the concentric wrapping of multiple layers of oligodendrocyte membrane around neuronal axons.
Strachan, D., Susan C Barnett, Edgar Julia M., David Strachan (186501), Ioannidou, K., Julia M Edgar, Kurt I Anderson, Susan C. Barnett (186504), David Strachan, Julia M. Edgar (37537), Anderson, K.I., Barnett, S.C., Strachan David, Kalliopi Ioannidou, Kurt I. Anderson (186499), Edgar, J.M., Kalliopi Ioannidou (186497), Ioannidou Kalliopi, Anderson Kurt I., Barnett Susan C.   +19 more
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Myelin-associated proteins are potential diagnostic markers in patients with primary brain tumour

, 2021
Taking into account the possibility of myelin-associated proteins having a role in brain tumour development, the study aimed to evaluate the diagnostic usefulness of myelin-associated proteins (Nogo-A, MAG, OMgp) released into extracellular space in ...
Ewa Matuszczak (4821702), Olga M. Koper-Lenkiewicz (11602751), Mariusz W. Mucha (11602769), Karol Sawicki (11602757), Joanna Matowicka-Karna (9344574), Violetta Dymicka-Piekarska (9344568), Robert Pawlak (400743), Joanna Reszeć (9344565), Marzena Tylicka (4821696), Anna J. Milewska (11602754), Joanna Kamińska (8886032), Justyna Zińczuk (11602763), Robert Chrzanowski (11602760), Zenon Mariak (11602766)   +13 more
core   +1 more source

Glycoproteins as targets of autoantibodies in CNS inflammation: MOG and more [PDF]

, 2012
B cells and antibodies constitute an important element in different inflammatory diseases of the central nervous system (CNS). Autoantibodies can serve as a biomarker to identify disease subgroups and may in addition contribute to the pathogenic process.
Mayer, Marie Cathrin, Meinl, Edgar, Marie Cathrin Mayer, Edgar Meinl, Meinl, E., Mayer, M.   +5 more
core   +1 more source

Clinical presentation and outcome in infantile Sandhoff disease: a case series of 25 patients from Iranian neurometabolic bioregistry with five novel mutations

Orphanet Journal of Rare Diseases, 2018
Background Infantile Sandhoff disease (ISD) is a GM2 gangliosidosis that is classified as a lysosomal storage disorder. The most common symptoms of affected individuals at presentation are neurologic involvement.
Ali Reza Tavasoli, Nima Parvaneh, Mahmoud Reza Ashrafi, Zahra Rezaei, Johannes Zschocke, Parastoo Rostami   +5 more
doaj   +1 more source

Myelin Peptide–Mannan Conjugate Multiple Sclerosis Vaccines: Conjugation Efficacy and Stability of Vaccine Ingredient

Vaccines, 2021
Myelin peptide–mannan conjugates have been shown to be potential vaccines in the immunotherapy of multiple sclerosis. The conjugates are comprised from the epitope peptide and the polysaccharide mannan which transfers as a carrier the antigenic peptide ...
John Matsoukas, George Deraos, Kostas Kelaidonis, Md Kamal Hossain, Jack Feehan, Andreas G. Tzakos, Elizabeth Matsoukas, Emmanuel Topoglidis, Vasso Apostolopoulos   +8 more
doaj   +1 more source

lnc’edin to Myelin [PDF]

Neuron, 2017
Long non-coding RNAs (lncRNAs) have been implicated in numerous developmental processes. In a technical and bioinformatics tour-de-force, He et al. (2017) provide critical insight into the dynamics of lncRNA expression, function, and mechanism during oligodendrocyte development and after injury.
Stacey M, Glasgow, Benjamin, Deneen
openaire   +2 more sources

The septin cytoskeleton is associated with distinct myelin structures of the central and peripheral nervous system [PDF]

, 2008
Rapid conduction of nerve impulses in the nervous system of higher vertebrates is made possible by ensheathment of nerve fibers by the specialized plasma membrane structure myelin. Consequently, failure of myelination or damage to the myelin sheath leads
Buser, Andres
core   +1 more source

Polyphosphoinositides in myelin [PDF]

Biochemical Journal, 1965
1. On fractionation of guinea-pig forebrain homogenates by differential and gradient-density centrifugation most of the polyphosphoinositides were recovered in the myelin-rich particles. 2. The phospholipids of pure preparations of myelin contained di- and tri-phosphoinositide in proportions 2-3 times greater than in the whole-brain phospholipids.
J, Eichberg, R M, Dawson
openaire   +2 more sources