Results 21 to 30 of about 228,458 (257)
Brain Sciences, 2022 Myelin in humans is composed of about 80% lipids and 20% protein. Initially, myelin protein composition was considered low, but various recent proteome analyses have identified additional myelin proteins.
Christos T. Chasapis +4 more
doaj +1 more source
Confined Multilamellae Prefer Cylindrical Morphology [PDF]
, 2005 By evaporating a drop of lipid dispersion we generate the myelin morphology often seen in dissolving surfactant powders. We explain these puzzling nonequilibrium structures using a geometric argument: The bilayer repeat spacing increases and thus the ...
Huang, Jung-Ren +2 more
core +1 more source
Focus on 1,25-Dihydroxyvitamin D3 in the Peripheral Nervous System
Frontiers in Neuroscience, 2019 In this review, we draw attention to the roles of calcitriol (1,25-dihydroxyvitamin D3) in the trophicity of the peripheral nervous system. Calcitriol has long been known to be crucial in phosphocalcium homeostasis. However, recent discoveries concerning
Pierre Antoine Faye +11 more
doaj +1 more source
Towards in vivo g-ratio mapping using MRI: unifying myelin and diffusion imaging [PDF]
, 2020 The g-ratio, quantifying the comparative thickness of the myelin sheath encasing an axon, is a geometrical invariant that has high functional relevance because of its importance in determining neuronal conduction velocity.
Callaghan, Martina F. +1 more
core +3 more sources
Orphanet Journal of Rare Diseases, 2019 Background Ribonucleases (RNases) are crucial for degradation of ribosomal RNA (rRNA). RNASET2 as a subtype of RNASEs is a 256 amino acid protein, encoded by RNASET2 gene located on chromosome six.
Reyhaneh Kameli +9 more
doaj +1 more source
Learning Myelin Content in Multiple Sclerosis from Multimodal MRI through Adversarial Training [PDF]
, 2018 Multiple sclerosis (MS) is a demyelinating disease of the central nervous system (CNS). A reliable measure of the tissue myelin content is therefore essential for the understanding of the physiopathology of MS, tracking progression and assessing ...
Ayache, Nicholas +6 more
core +3 more sources
Myelin pathology: Involvement of molecular chaperones and the promise of chaperonotherapy [PDF]
, 2019 The process of axon myelination involves various proteins including molecular chaperones. Myelin alteration is a common feature in neurological diseases due to structural and functional abnormalities of one or more myelin proteins.
Cappello F. +4 more
core +1 more source
EMBO Molecular Medicine, 2019 Current treatments in multiple sclerosis (MS) are modulating the inflammatory component of the disease, but no drugs are currently available to repair lesions.
Fabien Binamé +12 more
doaj +1 more source
MicroRNA-23a promotes myelination in the central nervous system. [PDF]
, 2013 Demyelinating disorders including leukodystrophies are devastating conditions that are still in need of better understanding, and both oligodendrocyte differentiation and myelin synthesis pathways are potential avenues for developing treatment ...
Fu, Ying-Hui +5 more
core +2 more sources
Bilateral horizontal gaze palsy in an 8‐year‐old girl: A rare case with NDUFS4 gene mutation
Clinical Case Reports, 2021 We report a patient with complex clinical presentation including multiple neurological symptoms and eye involvement. Upon genetic investigation, the patient was found to carry a novel homozygous mutation in the NDUFS4 gene, thus adding to the ...
Mohammad Vafaee‐Shahi +6 more
doaj +1 more source