Results 31 to 40 of about 51,525 (291)

Structural homology of myelin basic protein and muscarinic acetylcholine receptor: Significance in the pathogenesis of complex regional pain syndrome

Molecular Pain, 2018
Complex regional pain syndrome is an extremely painful condition that develops after trauma to a limb. Complex regional pain syndrome exhibits autoimmune features in part mediated by autoantibodies against muscarinic‐2 acetylcholine (M2) receptor.
Veronica I Shubayev, Alex Y Strongin, Tony L Yaksh   +2 more
doaj   +1 more source

Chronic Unpredictable Stress Reduces Immunostaining for Connexins 43 and 30 and Myelin Basic Protein in the Rat Prelimbic and Orbitofrontal Cortices

Chronic Stress, 2018
Background Astrocytes and oligodendrocytes are pathologically altered in dorsolateral prefrontal and orbitofrontal cortices in major depressive disorder.
José Javier Miguel-Hidalgo, Mohadetheh Moulana, Preston Hardin Deloach, Grazyna Rajkowska   +3 more
doaj   +1 more source

Lipid and basic protein interaction in myelin [PDF]

Biochemical Journal, 1974
1. Purified myelin labelled with [3H]myo-inositol or [1-14C]acetate was incubated with trypsin or acetylated trypsin at 37°C, pH8.0 for 30min. 2. After incubation and centrifugation analysis of the myelin pellet showed marked digestion of basic protein on polyacrylamide-gel electrophoresis. Proteolipid and Wolfgram proteins remained unchanged. 3.
N L, Banik, A N, Davison
openaire   +2 more sources

Glycoproteins as targets of autoantibodies in CNS inflammation: MOG and more [PDF]

, 2012
B cells and antibodies constitute an important element in different inflammatory diseases of the central nervous system (CNS). Autoantibodies can serve as a biomarker to identify disease subgroups and may in addition contribute to the pathogenic process.
Mayer, Marie Cathrin, Meinl, Edgar, Marie Cathrin Mayer, Edgar Meinl, Meinl, E., Mayer, M.   +5 more
core   +1 more source

Activation and expression of μ-calpain in dorsal root contributes to RTX-induced mechanical allodynia

Molecular Pain, 2017
Background Calpain is a calcium-dependent cysteine protease, and inhibition of calpain by pre-treatment with MDL28170 attenuated the rat mechanical allodynia in a variety of pain models. Postherpetic neuralgia (Shingles) is a neuropathic pain conditioned
Xiao-Cui Yuan, Cai-Hua Wu, Fang Gao, Hong-Ping Li, Hong-Chun Xiang, He Zhu, Xiao-Li Pan, Li-Xue Lin, Yan-Shen Liu, Wei Yu, Bo Tian, Xian-Fang Meng, Man Li   +12 more
doaj   +1 more source

Loss of Myelin Basic Protein Function Triggers Myelin Breakdown in Models of Demyelinating Diseases

Cell Reports, 2016
Breakdown of myelin sheaths is a pathological hallmark of several autoimmune diseases of the nervous system. We employed autoantibody-mediated animal models of demyelinating diseases, including a rat model of neuromyelitis optica (NMO), to target myelin ...
Marie-Theres Weil, Wiebke Möbius, Anne Winkler, Torben Ruhwedel, Claudia Wrzos, Elisa Romanelli, Jeffrey L. Bennett, Lukas Enz, Norbert Goebels, Klaus-Armin Nave, Martin Kerschensteiner, Nicole Schaeren-Wiemers, Christine Stadelmann, Mikael Simons   +13 more
doaj   +1 more source

Central and peripheral dysmyelination in a 3‐year‐old girl with ring chromosome 18

Clinical Case Reports, 2019
Myelin basic protein (MBP) contributes to peripheral and central nervous system myelin. Developmental myelinopathies exist on a clinical spectrum, but MBP is not included on leukodystrophy or CMT gene panels.
Dawn Brianna Lammert, David Miedema, Josiree Ochotorena, Nienke Dosa, Kalliopi Petropoulou, Roger Robert Lebel, Ai Sakonju   +6 more
doaj   +1 more source

CONTENTS OF SERUM MYELIN BASIC PROTEIN-IGG ANTIBODIES COMPLEXES IN NORMAL PREGNANCY AND GESTOSIS

Медицинская иммунология, 2014
Serum levels of myelin basic protein (MBP)-bound immune complexes were studied in blood sera from women with gestosis, as compared with those in normal pregnancy and non-pregnant woman.
V. G. Levchenko, N. V. Maltseva, O. F. Lykova, T. V. Konysheva, V. N. Zorina   +4 more
doaj   +1 more source

Characterization of immune response to neurofilament light in experimental autoimmune encephalomyelitis [PDF]

, 2013
PMCID: PMC3856490This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided ...
Amor, Sandra, Gerritsen, W.H., Victor, M. (Marion), Peferoen-Baert, R., Gerritsen, Wouter, Kimberley Ummenthum, Reijerkerk, Arie, Puentes, F. (Fabiola), Baker, D., Amor, S, Fabiola Puentes, Ruth Huizinga, van der Star, BJ, Sandra Amor, van der Valk, P, Gerritsen, W. (Wouter), David Baker, van der Star, B.J., Regina Peferoen-Baert, Baker, David, Markus Kipp, Marion Victor, Amor, S., Star, B.J. (Baukje) van der, Arie Reijerkerk, Puentes, F., Pryce, Gareth, Baker, D, Victor, Marion, Pryce, K. (Karena), Victor, M., Victor, M, Peferoen-Baert, R, Paul van der Valk, Kipp, M., Ummenthum, K, Victor, Marion Barbara, Beyer, C. (Cordian), Huizinga, R., Baker, D.A. (David), Reijerkerk, A., van der Star, Baukje J., Peferoen-Baert, Regina, Ummenthum, K. (Kimberley), Puentes, F, Amor, S. (Sandra), Ummenthum, Kimberley, Cordian Beyer, Baukje J van der Star, Reijerkerk, A, Huizinga, Ruth, Ummenthum, K., Gareth Pryce, Peferoen-Baert, R.M.B. (Regina), Valk, P. (Paul) van der, Wouter Gerritsen, Huizinga, R, Puentes, Fabiola, Huizinga, R. (Ruth), Beyer, C., Kipp, M, Gerritsen, W, Kipp, Markus, Beyer, C, Beyer, Cordian, Reijerkerk, A. (Arie), Kipp, M. (Markus), Pryce, G, Pryce, G., van der Valk, P., van der Valk, Paul   +70 more
core   +1 more source

Fingolimod modulates microglial activation to augment markers of remyelination [PDF]

, 2011
Introduction Microglial activation in multiple sclerosis has been postulated to contribute to long-term neurodegeneration during disease. Fingolimod has been shown to impact on the relapsing remitting phase of disease by modulating autoreactive T-cell ...
Giovannoni Gavin, Jackson Samuel J, Jackson, SJ, Baker, D, Gavin Giovannoni, Baker David, Giovannoni, G, David Baker, Samuel J Jackson   +8 more
core   +1 more source