Results 31 to 40 of about 89,485 (332)

Structural and molecular characteristics of axons in the long head of the biceps tendon [PDF]

open access: yes, 2020
The innervation of the long head of the biceps tendon (LHBT) is not sufficiently documented. This is a drawback since pathologies of the LHBT are a major source of shoulder pain.
Blumer, Roland   +7 more
core   +1 more source

Chronic Unpredictable Stress Reduces Immunostaining for Connexins 43 and 30 and Myelin Basic Protein in the Rat Prelimbic and Orbitofrontal Cortices

open access: yesChronic Stress, 2018
Background Astrocytes and oligodendrocytes are pathologically altered in dorsolateral prefrontal and orbitofrontal cortices in major depressive disorder.
José Javier Miguel-Hidalgo   +3 more
doaj   +1 more source

Loss of Myelin Basic Protein Function Triggers Myelin Breakdown in Models of Demyelinating Diseases

open access: yesCell Reports, 2016
Breakdown of myelin sheaths is a pathological hallmark of several autoimmune diseases of the nervous system. We employed autoantibody-mediated animal models of demyelinating diseases, including a rat model of neuromyelitis optica (NMO), to target myelin ...
Marie-Theres Weil   +13 more
doaj   +1 more source

Emerging immunopharmacological targets in multiple sclerosis. [PDF]

open access: yes, 2015
Inflammatory demyelination of the central nervous system (CNS) is the hallmark of multiple sclerosis (MS), a chronic debilitating disease that affects more than 2.5 million individuals worldwide. It has been widely accepted, although not proven, that the
Abdolmohamad Rostami   +182 more
core   +2 more sources

Activation and expression of μ-calpain in dorsal root contributes to RTX-induced mechanical allodynia

open access: yesMolecular Pain, 2017
Background Calpain is a calcium-dependent cysteine protease, and inhibition of calpain by pre-treatment with MDL28170 attenuated the rat mechanical allodynia in a variety of pain models. Postherpetic neuralgia (Shingles) is a neuropathic pain conditioned
Xiao-Cui Yuan   +12 more
doaj   +1 more source

Methylation-dependent PAD2 upregulation in multiple sclerosis peripheral blood [PDF]

open access: yes, 2012
Background: Peptidylarginine deiminase 2 (PAD2) and peptidylarginine deiminase 4 (PAD4) are two members of PAD family which are over-expressed in the multiple sclerosis (MS) brain.
ANNIBALI, Viviana   +9 more
core   +1 more source

Polyunsaturated fatty acids in the pathogenesis and treatment of multiple sclerosis [PDF]

open access: yes, 2007
Epidemiological, biochemical, animal model and clinical trial data described in this overview strongly suggest that polyunsaturated fatty acids, particularly n-6 fatty acids, have a role in the pathogenesis and treatment of multiple sclerosis (MS).
Copeland   +16 more
core   +2 more sources

Central and peripheral dysmyelination in a 3‐year‐old girl with ring chromosome 18

open access: yesClinical Case Reports, 2019
Myelin basic protein (MBP) contributes to peripheral and central nervous system myelin. Developmental myelinopathies exist on a clinical spectrum, but MBP is not included on leukodystrophy or CMT gene panels.
Dawn Brianna Lammert   +6 more
doaj   +1 more source

CONTENTS OF SERUM MYELIN BASIC PROTEIN-IGG ANTIBODIES COMPLEXES IN NORMAL PREGNANCY AND GESTOSIS

open access: yesМедицинская иммунология, 2014
Serum levels of myelin basic protein (MBP)-bound immune complexes were studied in blood sera from women with gestosis, as compared with those in normal pregnancy and non-pregnant woman.
V. G. Levchenko   +4 more
doaj   +1 more source

Evidence for gliadin antibodies as causative agents in schizophrenia. [PDF]

open access: yes, 2010
Antibodies to gliadin, a component of gluten, have frequently been reported in schizophrenia. Highly immunogenic B cell epitopes along its length are homologous to numerous proteins relevant to schizophrenia, including members of the DISC1 interactome ...
Chris J. Carter
core   +2 more sources

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