Results 51 to 60 of about 212,147 (360)

Characterization of immune response to neurofilament light in experimental autoimmune encephalomyelitis [PDF]

, 2013
PMCID: PMC3856490This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided ...
Amor, S, Baker, D, Beyer, C, Gerritsen, W, Huizinga, R, Kipp, M, Peferoen-Baert, R, Pryce, G, Puentes, F, Reijerkerk, A, Ummenthum, K, van der Star, BJ, van der Valk, P, Victor, M   +13 more
core   +4 more sources

A companion to the preclinical common data elements and case report forms for in vivo rodent neuroimaging: A report of the TASK3‐WG3 Neuroimaging Working Group of the ILAE/AES Joint Translational Task Force

Epilepsia Open, EarlyView., 2022
Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force established the TASK3 working groups to create common data elements (CDEs) for various aspects of preclinical epilepsy research studies, which could help improve the standardization of experimental designs.
Erwin A. van Vliet, Riikka Immonen, Ofer Prager, Alon Friedman, Jens P. Bankstahl, David K. Wright, Terence J. O'Brien, Heidrun Potschka, Olli Gröhn, Neil G. Harris   +9 more
wiley   +1 more source

Age-dependent differences in myelin basic protein expression in the hippocampus of young, adult and aged gerbils

Laboratory Animal Research, 2017
Myelin degeneration is one of the characteristics of aging and degenerative diseases. This study investigated age-related alterations in expression of myelin basic protein (MBP) in the hippocampal subregions (dentate gyrus, CA2/3 and CA1 areas) of ...
Ji Hyeon Ahn, Tae-Kyeong Lee, Joon Ha Park, Jeong Hwi Cho, In Hye Kim, Jae Chul Lee, Seongkweon Hong, Yong Hwan Jeon, Il Jun Kang, Young Joo Lee, Moo-Ho Won, Choong-Hyun Lee   +11 more
doaj   +1 more source

Central and peripheral dysmyelination in a 3‐year‐old girl with ring chromosome 18

Clinical Case Reports, 2019
Myelin basic protein (MBP) contributes to peripheral and central nervous system myelin. Developmental myelinopathies exist on a clinical spectrum, but MBP is not included on leukodystrophy or CMT gene panels.
Dawn Brianna Lammert, David Miedema, Josiree Ochotorena, Nienke Dosa, Kalliopi Petropoulou, Roger Robert Lebel, Ai Sakonju   +6 more
doaj   +1 more source

Methylation-dependent PAD2 upregulation in multiple sclerosis peripheral blood [PDF]

, 2012
Background: Peptidylarginine deiminase 2 (PAD2) and peptidylarginine deiminase 4 (PAD4) are two members of PAD family which are over-expressed in the multiple sclerosis (MS) brain.
ANNIBALI, Viviana, CAIAFA, Paola, CALABRESE, ROBERTA, CICCARONE, FABIO, COARELLI, GIULIA, GUASTAFIERRO, Tiziana, MECHELLI, Rosella, SALVETTI, Marco, UMETON, RENATO, ZAMPIERI, Michele   +9 more
core   +1 more source

CONTENTS OF SERUM MYELIN BASIC PROTEIN-IGG ANTIBODIES COMPLEXES IN NORMAL PREGNANCY AND GESTOSIS

Медицинская иммунология, 2014
Serum levels of myelin basic protein (MBP)-bound immune complexes were studied in blood sera from women with gestosis, as compared with those in normal pregnancy and non-pregnant woman.
V. G. Levchenko, N. V. Maltseva, O. F. Lykova, T. V. Konysheva, V. N. Zorina   +4 more
doaj   +1 more source

Autophagic degradation of CNS myelin maintains axon integrity

Cell Stress, 2022
(Macro)autophagy is a major lysosome-dependent degradation mechanism which engulfs, removes and recycles unwanted cytoplasmic material, including damaged organelles and toxic protein aggregates.
Niki Ktena, Stefanos Ioannis Kaplanis, Irina Kolotuev, Alexandros Georgilis, Emmanouela Kallergi, Vasiliki Stavroulaki, Vassiliki Nikoletopoulou, Maria Savvaki, Domna Karagogeos   +8 more
doaj   +1 more source

Conformational choreography of a molecular switch region in myelin basic protein—Molecular dynamics shows induced folding and secondary structure type conversion upon threonyl phosphorylation in both aqueous and membrane-associated environments [PDF]

, 2010
The 18.5kDa isoform of myelin basic protein is essential to maintaining the close apposition of myelin membranes in central nervous system myelin, but its intrinsic disorder (conformational dependence on environment), a variety of post-translational ...
Coll, Eoin P., Harauz, George, Polverini, Eugenia, Tieleman, D. Peter   +3 more
core   +1 more source

How Does Protein Zero Assemble Compact Myelin?

Cells, 2020
Myelin protein zero (P0), a type I transmembrane protein, is the most abundant protein in peripheral nervous system (PNS) myelin—the lipid-rich, periodic structure of membrane pairs that concentrically encloses long axonal segments.
Arne Raasakka, Petri Kursula
doaj   +1 more source

MENGA: a new comprehensive tool for the integration of neuroimaging data and the Allen human brain transcriptome atlas [PDF]

, 2016
Brain-wide mRNA mappings offer a great potential for neuroscience research as they can provide information about system proteomics. In a previous work we have correlated mRNA maps with the binding patterns of radioligands targeting specific molecular ...
Bertoldo, A, Expert, P, Rizzo, G, Turkheimer, FE, Veronese, M   +4 more
core   +4 more sources