Results 101 to 110 of about 163,909 (218)

Paramagnetic Rim Lesions Are Associated With Trans‐Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis

Annals of Clinical and Translational Neurology, Volume 13, Issue 9, Page 1831-1841, September 2026.
ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem, Angel Liu, Sargis Manukyan, Mustafa Subhi, Elaina Luskin, Bryan Quah, Sreekanth Madhusoodhanan Nair, Arzu C. Has Silemek, Gabriela Zabala, Yujie Cui, Laura Locke, Paula Barreras, Marwa Kaisey, Vinicius Calsavara, Daniel S. Reich, Nancy L. Sicotte, Pascal Sati, Omar Al‐Louzi   +17 more
wiley   +1 more source

Characterization of immune response to neurofilament light in experimental autoimmune encephalomyelitis [PDF]

, 2013
PMCID: PMC3856490This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided ...
Amor, Sandra, Gerritsen, W.H., Victor, M. (Marion), Peferoen-Baert, R., Gerritsen, Wouter, Kimberley Ummenthum, Reijerkerk, Arie, Puentes, F. (Fabiola), Baker, D., Amor, S, Fabiola Puentes, Ruth Huizinga, van der Star, BJ, Sandra Amor, van der Valk, P, Gerritsen, W. (Wouter), David Baker, van der Star, B.J., Regina Peferoen-Baert, Baker, David, Markus Kipp, Marion Victor, Amor, S., Star, B.J. (Baukje) van der, Arie Reijerkerk, Puentes, F., Pryce, Gareth, Baker, D, Victor, Marion, Pryce, K. (Karena), Victor, M., Victor, M, Peferoen-Baert, R, Paul van der Valk, Kipp, M., Ummenthum, K, Victor, Marion Barbara, Beyer, C. (Cordian), Huizinga, R., Baker, D.A. (David), Reijerkerk, A., van der Star, Baukje J., Peferoen-Baert, Regina, Ummenthum, K. (Kimberley), Puentes, F, Amor, S. (Sandra), Ummenthum, Kimberley, Cordian Beyer, Baukje J van der Star, Reijerkerk, A, Huizinga, Ruth, Ummenthum, K., Gareth Pryce, Peferoen-Baert, R.M.B. (Regina), Valk, P. (Paul) van der, Wouter Gerritsen, Huizinga, R, Puentes, Fabiola, Huizinga, R. (Ruth), Beyer, C., Kipp, M, Gerritsen, W, Kipp, Markus, Beyer, C, Beyer, Cordian, Reijerkerk, A. (Arie), Kipp, M. (Markus), Pryce, G, Pryce, G., van der Valk, P., van der Valk, Paul   +70 more
core   +2 more sources

Anti‐TNF‐Alpha Associated Central Nervous System Demyelination. Drug‐Induced Demyelination or Multiple Sclerosis Trigger? A Case Series

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Adalimumab is a monoclonal antibody that targets TNF‐α and is effective in treating several autoimmune disorders, including non‐infectious uveitis; however, it has been associated with demyelinating lesions. This study presents two cases of CNS demyelination in patients who consumed adalimumab. First, an 18‐year‐old man presented with subacute
Marzie Abutorabi‐zarchi, Amin Ziyaei, Davoud Ghane   +2 more
wiley   +1 more source

Quantitative analysis of aquaporin-4 (AQP4) and myelin oligodendrocyte glycoprotein (MOG) antibodies titres: correlation with relapses [PDF]

Detection of antibodies against aquaporin-4 (AQP4-IgG) and myelin oligodendrocyte glycoprotein (MOG-IgG) is essential for diagnosis of AQP4-IgG+ neuromyelitis optica spectrum disorder and myelin oligodendrocyte glycoprotein antibody-associated disease ...
Nasello, Martina, Leite, Maria Isabel, Xue, Huiru, Mgbachi, Victor, Palace, Jacqueline, Woodhall, Mark, Waters, Patrick, Geraldes, Ruth   +7 more
core   +1 more source

ICU Management of COVID-19 vaccine-related myelin oligodendrocyte glycoprotein IgG-association encephalomyelitis

, 2022
This is a 19 y.o. woman with a history of bipolar disorder admitted to the hospital for Myelin Oligodendrocyte Glycoprotein IgG-Associated Encephalomyelitis. She received her COVID-19 vaccination 5 days prior to symptom onset.
Vrtar, Andrew, Haddad, Moshe, Soto, Roy G   +2 more
core   +1 more source

Prolonged Headache in a 13‐Year‐Old Girl With Acute Lymphoblastic Leukemia: A Case of Possible Neuroinflammatory Complication Responsive to Intravenous Immunoglobulin

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Neurological complications in pediatric acute lymphoblastic leukemia (ALL) may result from disease, CNS involvement, or treatment. We report a 13‐year‐old girl with persistent headache and blurred vision suggestive of raised intracranial pressure.
Amereh Hadizadeh, Hossein Esfahani, Firozeh Hosseini, Afshin Fayyazi, Nasibeh Ghalandari   +4 more
wiley   +1 more source

Antibodies to Oligodendrocyte Glycoprotein in Children with ADEM

Pediatric Neurology Briefs, 2010
Antibodies to native myelin oligodendrocyte glycoprotein (nMOG) in 47 children during a first episode of CNS demyelination (acute disseminated encephalomyelitis [ADEM] in 19, and a clinical isolated syndrome [CIS] in 28) were investigated by a cell-based
J Gordon Millichap
doaj   +1 more source

Recent Advancements in Drug Delivery Across the Blood–Brain Barrier in Amyotrophic Lateral Sclerosis (ALS)

CNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
Progressive BBB/BSCB dysfunction is increasingly recognized as both a pathological feature and a therapeutic barrier in ALS. Novel delivery technologies and barrier‐restoration strategies may enhance CNS drug exposure, improve the efficacy of disease‐modifying therapies, and advance ALS treatment. ABSTRACT Background Amyotrophic lateral sclerosis (ALS)
Nitesh Sanghai, Kaitlyn Pierce, Nidhi Sharma, Sasha Leggett, Tara Chand Yadav, Pegah Masrori, Devi Atukorallaya, Senthilnathan Palaniyandi, Paul C. Marcogliese, Geoffrey K. Tranmer   +9 more
wiley   +1 more source

Asymptomatic Optic Nerve Enhancement in Myelin Oligodendrocyte Glycoprotein Associated Disease

, 2022
The rate of asymptomatic optic nerve enhancement on magnetic resonance imaging (MRI) has been reported as high as 51% in neuromyelitis optica (1), but has not been explored in patients with myelin oligodendrocyte glycoprotein antibody associated disease (
Mary Labowsky; Sanders Chang; Himanshu Sharma; Puneet Belani; Michael Schecht; Bradley Delman; Mark Kupersmith
core  

Emodin Suppresses the RAGE/ROCK1 Pathway to Modulate the Oligodendrocyte Lineage and Ameliorate Demyelination in Vascular Dementia Rats

CNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
Emodin improves white matter remyelination and alleviates cognitive deficits through suppression of the RAGE/ROCK1 signaling pathway in VD rats. Mechanistically, it modulates the OL lineage by reducing the elevated proliferative response of OPCs while promoting their maturation and remyelination.
Xueqing Wang, Xiumei Dong, Cunbao He, Junjie Zhang, Wenming Ban, Guoqi Zhu, Jingji Wang, Yilan Zhen   +7 more
wiley   +1 more source