Results 211 to 220 of about 119,819 (305)

Systemic and Local Adiposity in the Bone Marrow Microenvironment Associated With Improved Prognosis in Hodgkin Lymphoma: Imaging and Molecular Analysis

International Journal of Cancer, EarlyView.
Schematic overview of systemic and bone marrow‐specific adiposity in Hodgkin Lymphoma (HL). Body Mass Index was associated with bone marrow (BM) involvement, relapse, and mortality (1). In contrast, increased yellow marrow density was associated with poorer prognosis (2).
Andreia Matos, William P. Cawthorn, Joana Marinho‐Dias, Sofia Ramalheira, Susana Roncon, Dulcineia Pereira, Teresa Ribeiro, Carla Rodrigues, Mário Mariz, Ana Miranda, Helena Brízido, Manuel Bicho, Pedro Medeiros, Ana Carneiro, Fernanda Trigo, Pingzhao Hu, Flávia Pereira, Hugo Duarte, Calum D. Gray, Tom Macgillivray, Alan G. Ramsay, Maria J. Oliveira, Ricardo Ribeiro   +22 more
wiley   +1 more source

Developmental Profiling of Structural and Functional Maturation in Mouse Corpus Callosum. [PDF]

Glia
Johnson H, Beall M, Latifi S, Peng J, Sun W.   +4 more
europepmc   +1 more source

The Role of Endothelin‐1 in Autoimmune Diseases: Mechanistic Insights and Therapeutic Targets

iNew Medicine, EarlyView.
The Role of Endothelin‐1 in Autoimmune Diseases. NF‐κB: nuclear factor kappa‐B; MAPK: mitogen‐activated protein kinase; PI3K: phosphoinositide 3‐kinase; ROS: reactive oxygen species; CTGF: connective tissue growth factor; TGF‐β: transforming growth factor‐β.
Xun Gong, Zhenyu Wang, Suyin Yang, Kaige Gao, Xin Yang, Min Tang   +5 more
wiley   +1 more source

Glial Ion Channels in Myelin Pathophysiology: Insights from Leukodystrophies. [PDF]

Life (Basel)
Belfiore M, Visentin S, Ambrosini E.
europepmc   +1 more source

A Tripartite Model for EBV‐Driven Multiple Sclerosis: B Cell Survival, Altered Self‐Presentation, and HLA‐DR15‐Restricted T Cell Cross‐Reactivity

iNew Medicine, EarlyView.
ABSTRACT This commentary integrates findings from three recent Cell reports to establish a unified mechanistic model of multiple sclerosis (MS) driven by the interplay between Epstein‐Barr virus (EBV) and the HLA‐DR15 genotype. EBV promotes CNS autoimmunity through three distinct but intersecting mechanisms.
Fang Zhu, Arnaud John Kombe Kombe, Tengchuan Jin   +2 more
wiley   +1 more source

Alzheimer's Disease-Associated Molecular Abnormalities in White Matter Glia and Related Pathologies Detected in Unfractionated and O4-Selected Serum Exosomes Using a Liquid Biopsy Approach. [PDF]

Biomedicines
de la Monte SM, Tong M.
europepmc   +1 more source

Safety Assessment and Hypoglycemic Effect of Moringa oleifera Lam. Seed Lectin (WSMoL) in Alloxan‐Induced Diabetic Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT Moringa oleifera Lam. seeds contain WSMoL, a lectin previously studied for toxicity and pharmacological effects. In this study, we investigated WSMoL (10, 25, or 50 mg/kg i.p.) for acute and 14‐day repeated‐dose toxicity, as well as genotoxicity, in Swiss mice.
Alícia Natalie Silva dos Santos, Matheus Cavalcanti de Barros, Cleidiane Silva Vieira de Souza, Ryan Cristian da Silva, Luana Cassandra Breitenbach Barroso Coelho, Maria Tereza dos Santos Correia, Fernanda das Chagas Ângelo Mendes Tenório, Alisson Macário de Oliveira, Thiago Henrique Napoleão, Robson Raion de Vasconcelos Alves, Patrícia Maria Guedes Paiva   +10 more
wiley   +1 more source

ABCA1: A Therapeutic Target for Improving Cholesterol Homeostasis in Peripheral Neuropathies. [PDF]

Biomolecules
Woo YH, Schmidt NE, Johansson JO, Notterpek L.   +3 more
europepmc   +1 more source

Large‐Scale Evaluation of Traditional Chinese Medicines Reveals Potential PPARγ Modulators for Type 2 Diabetes Management

Journal of Clinical Laboratory Analysis, EarlyView.
Identifying novel treatments for diabetic management is always a competitive research topic all over the world. PPAR‐γ is one of the key regulators involved in glucose and lipid metabolism and improves insulin sensitivity and glucose homeostasis. This study investigated the impacts of 639 traditional Chinese medicine (TCM) on PPAR‐γ gene promoter ...
Mingyuan Dou, Shandra Jones, Juan Montes, Jonathan Ritter, Li‐Yu Shih, Chia‐Jung Chan, Ying‐Chou Lin, Min Chen, Shih‐Yin Chen, Ning Wu   +9 more
wiley   +1 more source

Alterations in cerebrospinal fluid levels of myelin- and oligodendrocyte-related proteins in sporadic Creutzfeldt-Jakob disease. [PDF]

Acta Neuropathol Commun
Maass F, Thomas C, Kurvits L, Hermann P, Schmitz M, Bähr M, Stadelmann C, Zechel S, Canaslan S, Zerr I.   +9 more
europepmc   +1 more source