Results 231 to 240 of about 119,819 (305)

Dasatinib and quercetin prevent alveolar bone loss in aged mice

Journal of Periodontology, EarlyView.
Abstract Background Recent findings have associated alveolar bone loss (ABL) with the presence of senescent cells. Aging and the accumulation of senescent cells are associated with a pro‐inflammatory environment which may exacerbate tissue damage.
Luisa S. Battistelli, Renata M. Moraes, Yuri C. Santos, Jaqueline L. Ribeiro, Maíra T. Garcia, Renata F. Prado, Florent Elefteriou, Ana Lia Anbinder   +7 more
wiley   +1 more source

Interleukin-Mediated Inflammatory Pathways and Nerve Injury in Lumbar Disc Herniation: A Narrative Review. [PDF]

Int J Gen Med
Wang D, Zhao D, Li X.
europepmc   +1 more source

Delayed diagnosis of 3β‐HSD7 deficiency in adolescence: Two case reports and review of the literature

JPGN Reports, EarlyView.
ABSTRACT Congenital bile acid synthesis defects (BASD), the most common of which is 3β‐hydroxy‐Δ5‐C27‐steroid dehydrogenase oxidoreductase (3β‐HSD7) deficiency, are a rare cause of fat‐soluble vitamin malabsorption. We describe a 14‐year‐old girl who presented at 14 months with a left distal femur fracture and failure to thrive.
Samantha Pendleton, Mojdeh Mostafavi, Jamie Mathew, Kayla Ganzburg, Barry Hirsch, Nadia Ovchinsky, Wael Sayej   +6 more
wiley   +1 more source

5-HT1B receptor agonists promote Schwann cell myelination. [PDF]

PLoS One
Kobayashi-Ujiie Y, Hiraki-Kamon K, Wakatsuki S, Araki T.   +3 more
europepmc   +1 more source

Lysosome Evanescence Mediates Autophagic Flux Impairment in Glucose Imbalanced Environments

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Schwann cells (SCs) support axonal function and promote nerve regeneration. This study investigated how various glucose concentrations influence SC viability, oxidative stress, and autophagy, which contribute to diabetic neuropathy. RSC96 SCs were cultured under five glucose conditions (0, 2.5, 5.5, 50, or 100 mM) for 24, 48, and 72 h.
Yuan‐Chen Cheng, Ling‐Li Chang, Hung‐Chen Wang, Wei‐Chun Hung, Chia‐Hua Hsieh, Yi‐Hsuan Wang, Kuang‐I Cheng   +6 more
wiley   +1 more source

Protective Effects of Riociguat Against Contrast‐Induced Nephropathy: An Experimental and Machine Learning‐Based Study in Rats

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Contrast‐induced nephropathy (CIN) is an important cause of acute kidney injury following exposure to iodinated contrast media, and effective preventive strategies remain limited. This study investigated the renoprotective effects of riociguat, a soluble guanylate cyclase stimulator, in an experimental rat model of CIN and explored machine ...
Mustafa Begenc Tascanov, Kenan Toprak, Sibel Turedi, İsmail Koyuncu, Zulkif Tanrıverdi, Necip Fazıl Dedeoglu, Halil Fedai, Asuman Bicer, İbrahim Halil Altıparmak, Recep Demirbag, Gencay Sarıısık   +10 more
wiley   +1 more source

Very long chain sphingolipids govern brain myelination by regulating oligodendrocyte differentiation and membrane microdomain integrity. [PDF]

J Transl Med
Sun H, Mo L, Cao M, Tian Y, Mo L, Ni Z, Zhang S, Huang X, Wang Y, Lam SM, Shui G.   +10 more
europepmc   +1 more source

Robotic arm‐assisted total knee arthroplasty reduces postoperative inflammatory response and blood loss compared to manual total knee arthroplasty: A matched‐pairs analysis of 688 patients

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Robotic arm‐assisted total knee arthroplasty (raTKA) has demonstrated several advantages over manual TKA (mTKA), including enhanced early recovery. Reduced soft tissue trauma and avoidance of femoral intramedullary canal opening have been hypothesised to lower the systemic inflammatory response.
Dirk Müller, Igor Lazic, Benjamin Schloßmacher, Vincent Lallinger, Michael T. Hirschmann, Rüdiger von Eisenhart‐Rothe, Florian Pohlig   +6 more
wiley   +1 more source

Age-Related Decline in Myelin Markers and Oligodendrocyte Density in Rhesus Macaque Prefrontal Cortex. [PDF]

eNeuro
Zhang Y, Yao L, Lv L, Zhao B, Zhong K, Li J.   +5 more
europepmc   +1 more source

Generation and characterization of iPSC-derived microglia for in vitro modeling of stimuli-specific neuroimmune responses. [PDF]

Alzheimers Dement
Haskell AK, Kulas JA, Carter WE, Javens-Wolfe J, Hinkel RD, Moussaif M, Smiley JS, Lazaro O, Robertson S, Palkowitz AD, Lamb BT, Richardson TI, Dage JL, Chu S, Johnson T, Stancato LF, Syed AQ.   +16 more
europepmc   +1 more source