GPR56/ADGRG1 regulates development and maintenance of peripheral myelin [PDF]
Ackerman, Sarah D+9 more
core +1 more source
Microglial NF‐κB signaling increases M1‐like spinal microglia over time after spinal cord injury. Microglial NF‐κB signaling broadly affects gene expression in spinal cord. Microglial NF‐κB signaling modulates splenocytes acutely after spinal cord injury.
Micaela L. O'Reilly+8 more
wiley +1 more source
Oligodendrogenesis in Evolution, Development and Adulthood
Oligodendrocytes and myelin took shape in jawed vertebrates. During development, OPCs are originated from NSCs and then undergo differentiation into mature oligodendrocytes that supply myelin. OPCs persist in the adult CNS and continue to produce oligodendrocytes and myelin. Adaptive myelination, which fine‐tunes neural circuits in response to neuronal
Hao Hu+3 more
wiley +1 more source
Oligodendrocyte-specific overexpression of human alpha-synuclein results in elevated MBP levels and inflammatory responses in TgM83 mice, mimicking the pathological features of multiple system atrophy. [PDF]
Liu SC+5 more
europepmc +1 more source
Brain oligodendrocytes have lower rates of cholesterol synthesis and higher rates of lipoprotein uptake than spinal cord oligodendrocytes. Myelin lipid content is higher in CNS regions with larger average axon diameter. Brain and spinal cord myelin cholesterol content is innately different, while myelin fatty acid content can be modulated by fiber ...
Marie L. Mather+4 more
wiley +1 more source
Neuroplasticity After Hypoxic-Ischemic Brain Injury in Neonatal Pigs Based on Time-Dependent Behavior of <sup>1</sup>H-MRS-Tau Protein and Synaptic Associated Proteins and Synaptic Structure Analysis. [PDF]
Zhao S, Zheng Y.
europepmc +1 more source
What Does Iron Mean to an Oligodendrocyte?
ABSTRACT Iron is essential for life and plays a key role in multiple fundamental cellular functions. The brain has the highest rate of energy consumption, and within the brain, oligodendrocytes have the highest level of oxidative metabolism per volume. Oligodendrocytes also stain the strongest for iron.
Quinn W. Wade, James R. Connor
wiley +1 more source
Antibodies targeting ADAM17 reverse neurite outgrowth inhibition by myelin-associated inhibitors. [PDF]
Saha N+5 more
europepmc +1 more source
In vitro acylation of rat brain myelin proteolipid protein.
Laurace E. Townsend+3 more
openalex +1 more source
Studies on NG-methylarginine derivatives in myelin basic protein from developing and mutant mouse brain [PDF]
N Rawal+3 more
openalex +1 more source