Results 251 to 260 of about 130,050 (381)

Progressive Alcohol-Related Brain Atrophy and White Matter Pathology Are Linked to Long-Term Inhibitory Effects on mTOR Signaling. [PDF]

Biomolecules
Tong M, Homans C, Pelit W, Delikkaya B, de la Monte SM.   +4 more
europepmc   +1 more source

Post-transcriptional events are responsible for low expression of myelin basic protein in myelin deficient mice: role of natural antisense RNA. [PDF]

, 1990
Mirjana Toŝić, Arthur Roach, J.C. de Rivaz, M Dolivo, J.-M. Matthieu   +4 more
openalex   +1 more source

Somatic cell reprogramming for Parkinson's disease treatment

Ibrain, Volume 11, Issue 1, Page 59-73, Spring 2025.
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley   +1 more source

Purifying selection of the lysosomal enzymes arylsulfatase A and beta-galactocerebrosidase and their evolutionary impact on myelin integrity. [PDF]

J Lipid Res
Luetzen MA, Chakraborty R, Moreno-Ramos OA, Echeverri-Peña OY, Satta Y, Montaño AM.   +5 more
europepmc   +1 more source

Core promoter of the mouse myelin basic protein gene governs brain-specific transcription in vitro. [PDF]

, 1990
Takeshi Tamura, Kohsuke Sumita, Susumu Hirose, Katsuhiko Mikoshiba   +3 more
openalex   +1 more source

Immunomodulatory natural polysaccharide‐based nanoparticles for the treatment of neurodegenerative diseases

Ibrain, EarlyView.
Polysaccharide‐based nanoparticles offer versatile platforms for drug delivery and immune modulation in neurodegenerative diseases. This review highlights their potential in treating Alzheimer's, Parkinson's, and multiple sclerosis, focusing on targeted delivery and neuroinflammation.
Leto‐Aikaterini Tziveleka, Mariafrancesca Cascione, Paolo Pellegrino, Annalisa Bianco, Stefano Leporatti, Valeria De Matteis   +5 more
wiley   +1 more source

Thinning of originally-existing, mature myelin represents a nondestructive form of myelin loss in the adult CNS. [PDF]

Front Cell Neurosci
Lin ML, Lin W.
europepmc   +1 more source

Therapeutic targeting of chromatin alterations in leukemia and solid tumors

International Journal of Cancer, EarlyView.
Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner, Tobias Berg, Daniel Sasca, Sophie‐Luise Mersiowsky, Jayant Y. Gadrey, Johanna Thomas, Michael W. M. Kühn, Michael Lübbert   +7 more
wiley   +1 more source

Research status of regenerative difficulties after central nervous system injury. [PDF]

Regen Ther
Fu Y, Rui X, Zhu S, Guo C, Li H, Pan Z, Wu X, He W.   +7 more
europepmc   +1 more source

IgG subclasses of antibodies reacting with HIV and myelin basic protein in CSF from HIV infected patients

, 1988
Tiit Mathiesen, Anders Sönnerborg, B. Wahren   +2 more
openalex   +1 more source