Results 251 to 260 of about 5,666,125 (336)

Research progress on the use of the optical coherence tomography system for the diagnosis and treatment of central nervous system tumors

Ibrain, Volume 11, Issue 1, Page 3-18, Spring 2025.
With the advantages of high‐resolution imaging, efficient image acquisition, intraoperative real‐time detection, and radiation‐free and noninvasive characteristics, optical coherence tomography (OCT) provides accurate diagnosis and effective intraoperative guidance for the minimally invasive diagnosis and treatment of central nervous system (CNS ...
Jiuhong Li, Ziba Ayi, Gonggong Lu, Haibo Rao, Feilong Yang, Jing Li, Jiachen Sun, Junlin Lu, Xulin Hu, Si Zhang, Xuhui Hui   +10 more
wiley   +1 more source

Myelin Lipid Composition in the Central Nervous System Is Regionally Distinct and Requires Mechanistic Target of Rapamycin Signaling. [PDF]

Glia
Mather ML, Evangelou AV, Bourne JN, Macklin WB, Wood TL.   +4 more
europepmc   +1 more source

Somatic cell reprogramming for Parkinson's disease treatment

Ibrain, Volume 11, Issue 1, Page 59-73, Spring 2025.
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley   +1 more source

Inflammation's impact on the interaction between oligodendrocytes and axons. [PDF]

Discov Immunol
Green TRF, Pingen M, Edgar JM.
europepmc   +1 more source

Immunomodulatory natural polysaccharide‐based nanoparticles for the treatment of neurodegenerative diseases

Ibrain, EarlyView.
Polysaccharide‐based nanoparticles offer versatile platforms for drug delivery and immune modulation in neurodegenerative diseases. This review highlights their potential in treating Alzheimer's, Parkinson's, and multiple sclerosis, focusing on targeted delivery and neuroinflammation.
Leto‐Aikaterini Tziveleka, Mariafrancesca Cascione, Paolo Pellegrino, Annalisa Bianco, Stefano Leporatti, Valeria De Matteis   +5 more
wiley   +1 more source

Activation of XBP1s attenuates disease severity in models of proteotoxic Charcot-Marie-Tooth type 1B. [PDF]

Brain
Touvier T, Veneri FA, Claessens A, Ferri C, Mastrangelo R, Sorgiati N, Bianchi F, Valenzano S, Del Carro U, Rivellini C, Duong P, Shy ME, Kelly JW, Svaren J, Wiseman RL, D'Antonio M.   +15 more
europepmc   +1 more source

Magnesium Silicate Composite Patch With Neurovascular Regenerative Properties Promotes Diabetic Wound Healing in Mice

Interdisciplinary Materials, EarlyView.
The PCL‐PLLA‐MgSiO3 composite patch fabricated via electrospinning demonstrates superior therapeutic effects on diabetic wound healing compared to commercially available products, especially neurovascular network recovery. This will provide a promising bioactive patch for future clinical diabetic wound management.
Shunxiang Xu, Hongwei Shao, Zheyu Jin, Jiankun Xu, Fanyan Deng, Yuantao Zhang, Liangbin Zhou, Samuel Ka‐kin Ling, Congqin Ning, Wenxue Tong, Ling Qin   +10 more
wiley   +1 more source

Novel potential neuroprotective targets for DengZhanXiXin injection in middle cerebral artery occlusion rats recommended by quantitative proteomics and simulated docking. [PDF]

Front Neurosci
Li M, Wang L, An H, Li X, Chen Y, Wei D, Zhang Z.   +6 more
europepmc   +1 more source

Therapeutic targeting of chromatin alterations in leukemia and solid tumors

International Journal of Cancer, EarlyView.
Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner, Tobias Berg, Daniel Sasca, Sophie‐Luise Mersiowsky, Jayant Y. Gadrey, Johanna Thomas, Michael W. M. Kühn, Michael Lübbert   +7 more
wiley   +1 more source

Tubulin Polymerization Promoting Proteins: Functional Diversity With Implications in Neurological Disorders. [PDF]

J Neurosci Res
Diaz PJ, Shi Q, McNeish PY, Banerjee S.
europepmc   +1 more source