Results 121 to 130 of about 13,094 (201)

Spectral tracing of deuterium for imaging glucose metabolism. [PDF]

, 2019
Cells and tissues often display pronounced spatial and dynamical metabolic heterogeneity. Common glucose-imaging techniques report glucose uptake or catabolism activity, yet do not trace the functional utilization of glucose-derived anabolic products ...
Liu, Yinong, Miao, Yupeng, Min, Wei, Qian, Naixin, Shen, Yihui, Shi, Lingyan, Wei, Mian, Zhang, Luyuan   +7 more
core  

Identificación y uso de biomarcadores pronósticos en el ictus isquémico [PDF]

, 2012
II. Es van analitzar mostres de microdiàlisi cerebral in vivo de pacients d'ictus isquèmic pel descobriment de biomarcadors associats a la malaltia cerebrovascular. Es van obtenir microdialitzats (MDs) de la zona infartada, de la zona del periinfart i de
García Berrocoso, Teresa, Montaner, Joan, Universitat Autònoma de Barcelona. Departament de Medicina, Universitat Autònoma de Barcelona. Facultat de Medicina   +3 more
core  

Linking obesity-associated genotype to child language development: the role of early-life neurology-related proteomics and brain myelination

eBioMedicine
The association between childhood obesity and language development may be confounded by socio-environmental factors and attributed to comorbid pathways.In a longitudinal Singaporean mother-offspring cohort, we leveraged trans-ancestry polygenic predictions of body mass index (BMI) to interrogate the causal effects of early-life BMI on child language ...
Jian Huang, Jinyi Che, Michelle Z.L. Kee, Ai Peng Tan, Evelyn C. Law, Patricia Pelufo Silveira, Irina Pokhvisneva, Sachin Patel, Keith M. Godfrey, Lourdes Mary Daniel, Kok Hian Tan, Yap Seng Chong, Shiao-Yng Chan, Johan G. Eriksson, Dennis Wang, Jonathan Yinhao Huang   +15 more
openaire   +6 more sources

Proteomic signatures of physical, cognitive, and imaging outcomes in multiple sclerosis

Annals of Clinical and Translational Neurology
Background A quantitative measurement of serum proteome biomarkers that would associate with disease progression endpoints can provide risk stratification for persons with multiple sclerosis (PwMS) and supplement the clinical decision‐making process ...
Kian Jalaleddini, Dejan Jakimovski, Anisha Keshavan, Shannon McCurdy, Kelly Leyden, Ferhan Qureshi, Atiyeh Ghoreyshi, Niels Bergsland, Michael G. Dwyer, Murali Ramanathan, Bianca Weinstock‐Guttman, Ralph HB Benedict, Robert Zivadinov   +12 more
doaj   +1 more source

Mechanistic Insights of Gamma Sensory Stimulation: CSF Proteomic Analyses Reveal Changes in Myelin and Synaptic Proteins [PDF]

Alzheimers Dement
AbstractBackgroundPreclinical investigations in Alzheimer’s disease (AD) have highlighted the efficacy of gamma sensory stimulation in mitigating AD‐related pathologies. Cognito Therapeutics, Inc. (Cambridge, MA) has designed the Sensory Stimulation System for safe at‐home usage, to induce EEG‐confirmed gamma oscillations as a potential treatment for ...
Shpokayte M, Pandey K, Singer A, Doung D, Lah J, Levey A, Seyfried N, Malchano Z, Kern R, Hajos M.   +9 more
europepmc   +2 more sources

Myelin matters: proteomic insights into white matter disorders

Expert Review of Proteomics, 2010
Werner, H., Jahn, O.
openaire   +4 more sources

ASTROCYTE DYSFUNCTION IN AUTOSOMAL DOMINANT LEUKODYSTROPHY (ADLD): INSIGHTS FROM 2D AND 3D IN VITRO SYSTEMS AND EX VIVO CEREBROSPINAL FLUID METABOLOMICS

European Journal of Histochemistry
Autosomal Dominant Leukodystrophy (ADLD) is a rare, fatal neurodegenerative disorder caused by LMNB1 gene overexpression, leading to progressive central nervous system demyelination with no effective therapy.
doaj   +1 more source

Myelin Abnormalities in Schizophrenia: Insights from Proteomic Investigations of Post-Mortem Schizophrenia and Pre-Clinical Animal Models

, 2019
Accumulating evidence from epidemiologic and clinical findings report that both exposure to prenatal inflammation and prenatal iron deficiency significantly increase the risk of developing Schizophrenia in the offspring. Abnormalities in myelin are the most robust neuropathological findings in post-mortem human Schizophrenia, however the exact ...
openaire   +2 more sources

GPR56/ADGRG1 regulates development and maintenance of peripheral myelin [PDF]

, 2018
Ackerman, Sarah D, D\u27Rozario, Mitchell, et al,, Gamble, Paul, Harty, Breanne L, MacEwan, Matthew R, Mogha, Amit, Monk, Kelly R, Ray, Wilson Zachary, Sanchez, Nicholas E   +9 more
core   +1 more source

Proteomic Characterization of Spinal Cord Myelin in the Mouse. [PDF]

ASN Neuro
Schmitt O, Kaddatz H, Mikkat S, Kipp M, Schümann A, Joost S.   +5 more
europepmc   +1 more source