Results 101 to 110 of about 201,896 (346)
Di-san junyi daxue xuebao, 2020 Objective To explore the mechanisms by which Dexras1 promotes inflammation and participates in white matter damage (WMD) after subarachnoid hemorrhage (SAH). Methods Ninety healthy adult male SD rats were randomly divided into control group (sham group),
XIN Yuanjun +7 more
doaj +1 more source
Myelin organization in the nodal, paranodal, and juxtaparanodal regions revealed by scanning x-ray microdiffraction. [PDF]
PLoS ONE, 2014 X-ray diffraction has provided extensive information about the arrangement of lipids and proteins in multilamellar myelin. This information has been limited to the abundant inter-nodal regions of the sheath because these regions dominate the scattering ...
Hideyo Inouye +6 more
doaj +1 more source
Effects of normal aging on myelin sheath ultrastructures in the somatic sensorimotor system of rats.
Molecular Medicine Reports, 2014 Previous studies have presented qualitative and quantitative data regarding the morphological changes that occur peripherally in myelin sheaths and nerve fibers of rats during their lifespan.
Fang-Mei Xie +4 more
semanticscholar +1 more source
Myelin Fat Facts: An Overview of Lipids and Fatty Acid Metabolism
Cells, 2020 Myelin is critical for the proper function of the nervous system and one of the most complex cell–cell interactions of the body. Myelination allows for the rapid conduction of action potentials along axonal fibers and provides physical and trophic ...
Y. Poitelon +2 more
semanticscholar +1 more source
Endothelial PD‐1 Regulates Vascular Homeostasis and Oligodendrogenesis during Brain Development
Advanced Science, EarlyView.Vascular endothelial cells are fundamental for angiogenesis and brain development. This study reveals that endothelial programmed cell death 1 (PD‐1) is critical for cerebral angiogenesis and blood brain barrier (BBB) maturation. It also mediates interaction with oligodendrocyte precursor cells (OPCs), modulating OPCs differentiation and myelination ...
Tingting He +7 more
wiley +1 more source
Acta Medica Iranica, 2015 Multiple Sclerosis (MS) causes loss of the myelin sheath, which leads to loss of neurons. Regeneration of myelin sheath stimulates axon regeneration and neurons’ survival. In this study, olfactory ensheathing cell (OEC) transplantation is investigated to
Mohammad Azimi Alamouti +6 more
doaj
Neural Regeneration Research, 2023 The extracellular matrix surrounding oligodendrocytes plays an important role during myelination and remyelination in the brain. In many cases, the microenvironment surrounding demyelination lesions contains inhibitory molecules, which lead to repair ...
Ya-Jie Xiong +5 more
doaj +1 more source
MAGEA6 Engages a YY1‐Dependent Transcription to Dictate Perineural Invasion in Colorectal Cancer
Advanced Science, EarlyView.This study investigates the role of MAGEA6 in perineural invasion (PNI) in colorectal cancer (CRC). MAGEA6 promotes CRC invasiveness by inhibiting YY1 ubiquitination, enhancing CXCL1 secretion, and recruiting Schwann cells. These findings highlight the potential of targeting the MAGEA6/YY1/CXCL1 axis for therapeutic strategies against PNI and tumor ...
Hao Wang +9 more
wiley +1 more source
Cell vibron polariton in the myelin sheath of nerve [PDF]
arXiv, 2019 Polaritons are arousing tremendous interests in physics and material sciences for their unique and amazing properties, especially including the condensation, lasing without inversion and even room-temperature superfluidity. Herein, we propose a cell vibron polariton (cell-VP): a collectively coherent mode of a photon and all phospholipid molecules in a
arxiv
Natural History and Diagnostic Findings in an Adult Man Diagnosed With Attenuated Krabbe Disease
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Krabbe disease (KD), or globoid cell leukodystrophy, is a rare autosomal recessive lysosomal storage disorder caused by a deficiency in galactocerebrosidase (GALC), leading to psychosine (galactosylsphingosine) accumulation and myelin damage.
Eamon P. McCarron +8 more
wiley +1 more source