Results 121 to 130 of about 53,137 (327)

Studies on cultured Schwann cells: the induction of myelin synthesis, and the control of their proliferation by a new growth factor [PDF]

, 1981
We have recently described the use of immunological methods to identify and purify rat Schwann cells. In dissociated cultures of neonatal sciatic nerve, all of the cells can be identified by antigenic criteria as either Schwann cells or fibroblasts.
Brockes, J. P., Fryxell, K. J., Lemke, G. E.   +2 more
core  

Deciphering the conformational dynamics of Myelin Oligodendrocyte glycoprotein in the myelin sheath

Journal of Biomolecular Structure and Dynamics
Myelin Oligodendrocyte Glycoprotein (MOG) is a transmembrane protein in the myelin sheath. It acts as an auto-antigen under certain unknown conditions causing demyelination, thus resulting in Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease (MOGAD).
Y. K. Ananya, L. Ramya
openaire   +2 more sources

Silk fibroin‐based biomaterials for spinal cord injury repair: Recent advances and future prospects

BMEMat, EarlyView.
A comprehensive review on the design principles and current strategies of silk fibroin‐based biomaterials in spinal cord injury repair, focusing on environmentally friendly processing techniques, and the strategies for designing composite scaffolds as well as discussing the advantages and current challenges of silk fibroin‐based biomaterials in spinal ...
Xiaoliang Cui, Xuanwen Wang, Siying Liu, Lilei Wang, Menghong Li, Jun Zhang, Li Wang, Ke‐Qin Zhang   +7 more
wiley   +1 more source

Monitoring Treatment‐Associated Receptor Expression in Multiple Sclerosis Using a Newly Developed Panel for Spectral Flow Cytometry

Cytometry Part A, EarlyView.
ABSTRACT Multiple sclerosis (MS) is a chronic, immune‐mediated autoimmune disease characterized by the infiltration of autoreactive T cells and other inflammatory immune cells from the periphery into the central nervous system. Currently, there is no cure for MS, and treatment consists of disease‐modifying therapies (DMTs), most of which modify or ...
Katharina Robichon, Jennifer Taylor, Imogen Milner, Kathryn Elizabeth Hally, Anne Camille La Flamme   +4 more
wiley   +1 more source

Metabolite‐Guided Acetylation Therapy: Astragaloside IV Reverses Diabetic Nephropathy via Gna13‐Driven Purine Metabolic Reprogramming

Food Frontiers, EarlyView.
This study unveils how ASIV reverses diabetic nephropathy by restoring Gna13‐K363 acetylation and reprogramming purine metabolism. Using spatial metabolomics and acetylproteomics, we identified zonation‐specific purine dysregulation in diabetic kidneys, with ASIV normalizing metabolite distribution (hypoxanthine, cAMP, guanine) and targeting Gna13 ...
Shi Qiu, Sifan Guo, Dandan Xie, Zhibo Wang, Ying Cai, Xian Wang, Qiang Yang, Chunsheng Lin, Hong Yao, Qiqi Zhao, Yu Guan, Songqi Tang, Yiqiang Xie, Aihua Zhang   +13 more
wiley   +1 more source

Prolactin Receptor Deficiency Promotes Hypomyelination in White Matter Tracts During Postnatal Central Nervous System Maturation in Mice

Glia, EarlyView.
Prolactin action is essential for proper myelination of white matter tracts during neonatal and prepubertal stages in mice. Lack of prolactin receptor (Prlr−/−) signaling leads to hypomyelination and impaired locomotor function. ABSTRACT A large wave of myelination in the central nervous system (CNS) of mammals occurs during postnatal development ...
Ana L. Ocampo‐Ruiz, José L. Dena‐Beltrán, Marco A. Dimas‐Rufino, Ximena Castillo, Dina I. Vazquez‐Carrillo, Andrea Silos‐Guajardo, Xarubet Ruiz‐Herrera, Edith Garay, Gonzalo Martínez de la Escalera, Carmen Clapp, Rogelio O. Arellano, Abraham J. Cisneros‐Mejorado, Yazmín Macotela   +12 more
wiley   +1 more source

FURTHER OBSERVATIONS ON THE STRUCTURE OF MYELIN SHEATHS IN THE CENTRAL NERVOUS SYSTEM [PDF]

, 1964
Alan Peters
openalex   +1 more source

Oligodendroglial Densities and Myelin Structure Are Altered in TDP‐43 Related Amyotrophic Lateral Sclerosis

Glia, EarlyView.
TDP‐43Q331K mice exhibit altered proliferative dynamics in oligodendrocytes and their precursors. Oligodendroglial cell death is evident in TDP‐43Q331K mice. TDP‐43Q331K mice display altered myelin reflectance and pathology in the spinal cord. ABSTRACT Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease characterized by the ...
Katherine N. Lewis, Georgina A. Craig, Joel Mason, Doris Tomas, Brittany Cuic, Adam K. Walker, David G. Gonsalvez, Bradley J. Turner, Samantha K. Barton   +8 more
wiley   +1 more source

Histological and Ultrastructure of the Peripheral Nerve in Cadaveric Embalmed Specimens and in Fresh Cadavers: the Efficacy of Several Fixatives

Siriraj Medical Journal, 2009
Objective: The study is to observe the histological structure and the ultrastructure of the peripheral nerve from cadaveric embalmed specimens and from fresh specimens by light microscope and by transmission electron microscope.
Kunnika Chatyingmongkol, Jantima Roongruangchai, Kesorn Sripaoraya   +2 more
doaj  

Management of Retropharyngeal Lymph Node Metastases in Thyroid Cancer

Head &Neck, EarlyView.
ABSTRACT Background Retropharyngeal lymph node (RPLN) metastases in thyroid cancer are rare, with optimal management underreported. Methods Retrospective study of consecutive thyroid cancer patients with RPLN metastases treated at MD Anderson Cancer Center between 2000 and 2024.
Isabelle Fournier, Ashwini Venkata Bandi, Sarah Hamidi, Priyanka Iyer, Naifa L. Busaidy, Maria E. Cabanillas, Ramona Dadu, Mimi I. Hu, Steven G. Waguespack, Ugur Nur Basmaci, Michelle D. Williams, Mena Mansour, Maria Gule Monroe, Neil D. Gross, Ryan P. Goepfert, Nancy D. Perrier, Victoria Banuchi, Jennifer R. Wang, Anastasios Maniakas, Mark E. Zafereo   +19 more
wiley   +1 more source