Results 131 to 140 of about 201,896 (346)

Actin Polymerization Is Essential for Myelin Sheath Fragmentation during Wallerian Degeneration

open access: yesJournal of Neuroscience, 2011
The mechanisms that trigger Wallerian degeneration (WD) of peripheral nerves after injury are not well understood. During the early period of WD, fragmentation of myelin into ovoid structures occurs near the Schmidt-Lantermann incisures (SLI), a ...
Junyang Jung   +9 more
semanticscholar   +1 more source

The X‐Linked Intellectual Disability Gene, ZDHHC9, Is Important for Oligodendrocyte Subtype Determination and Myelination

open access: yesGlia, EarlyView.
Zdhhc9 ablation grossly changes gene expression and myelin protein levels in CNS WM. Zdhhc9 is important for the establishment of mature oligodendrocyte subtypes. Zdhhc9 is important for axon myelination and the maintenance of myelin integrity. ABSTRACT Two percent of patients with X‐linked intellectual disability (XLID) exhibit loss‐of‐function ...
Rocio B. White   +9 more
wiley   +1 more source

Deciphering the conformational dynamics of Myelin Oligodendrocyte glycoprotein in the myelin sheath

open access: yesJournal of Biomolecular Structure and Dynamics
Myelin Oligodendrocyte Glycoprotein (MOG) is a transmembrane protein in the myelin sheath. It acts as an auto-antigen under certain unknown conditions causing demyelination, thus resulting in Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease (MOGAD).
Y. K. Ananya, L. Ramya
openaire   +2 more sources

Research progress of neurovascular units involved in ischemic stroke

open access: yesIbrain, EarlyView.
The brain receives less blood when an ischemic stroke develops, which damages neurons and leads to an increased release of Pro‐inflammatory mediators that activate neurovascular unit (NVU). When the tight junctions are broken and the basement membrane is disrupted by matrix metalloproteinases produced by active endothelial and pericellular cells ...
Yu Yang   +4 more
wiley   +1 more source

Investigating the role of SARM1 in central nervous system

open access: yesIbrain, EarlyView.
Sterile‐α and Toll/interleukin 1 receptor (TIR) motif‐containing protein 1 (SARM1) is a pivotal molecule that has garnered extensive attention in neuroscience. As an intracellular molecule, SARM1 possesses various crucial biological functions in the nervous system.
Junjie Wang   +4 more
wiley   +1 more source

Fertility preservation in female cancer patients: Surgical procedures

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract The surgical management of cancer patients wishing fertility preservation is multidisciplinary, involving surgeon, anesthetist, hematologist, and nursing and laboratory staff. Many oncology patients have a multitude of medical or surgical conditions that require careful planning of all therapy including surgical removal of reproductive ...
Rishi Roopnarinesingh, Togas Tulandi
wiley   +1 more source

Efficacy of Neuromuscular Ultrasound in Diagnosing and Treating a Mammogram‐Induced Brachial Plexus Injury—A Case Report

open access: yesJournal of Clinical Ultrasound, EarlyView.
This case highlights the diagnostic challenges of cutaneous nerve entrapment syndromes, often overlooked and misdiagnosed, especially without a clear inciting injury. Through the utilization of musculoskeletal ultrasound, peripheral neuropathies can be diagnosed and treated successfully. ABSTRACT A 40‐year‐old woman presented with chronic left anterior
Jaime Dougherty   +2 more
wiley   +1 more source

Improving the Detection of Myelin Integrity in Multiple Sclerosis Using Selective Inversion Recovery for MRI With Quantitative Magnetization Transfer

open access: yesJournal of Magnetic Resonance Imaging, EarlyView.
Background Selective inversion recovery quantitative magnetization transfer (SIR‐qMT)‐derived macromolecular to free water pool size ratio (PSR) and diffusion tensor imaging (DTI)‐derived radial diffusivity (RD) are potential metrics for assessing myelin integrity in multiple sclerosis (MS).
Ahmad A. Toubasi   +10 more
wiley   +1 more source

Histological and Ultrastructure of the Peripheral Nerve in Cadaveric Embalmed Specimens and in Fresh Cadavers: the Efficacy of Several Fixatives

open access: yesSiriraj Medical Journal, 2009
Objective: The study is to observe the histological structure and the ultrastructure of the peripheral nerve from cadaveric embalmed specimens and from fresh specimens by light microscope and by transmission electron microscope.
Kunnika Chatyingmongkol   +2 more
doaj  

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