Results 131 to 140 of about 48,603 (346)
Deciphering the conformational dynamics of Myelin Oligodendrocyte glycoprotein in the myelin sheath
Journal of Biomolecular Structure and DynamicsMyelin Oligodendrocyte Glycoprotein (MOG) is a transmembrane protein in the myelin sheath. It acts as an auto-antigen under certain unknown conditions causing demyelination, thus resulting in Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease (MOGAD).
Y. K. Ananya, L. Ramya
openaire +2 more sources
Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy
Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley +1 more source
Research progress of neurovascular units involved in ischemic stroke
Ibrain, EarlyView.The brain receives less blood when an ischemic stroke develops, which damages neurons and leads to an increased release of Pro‐inflammatory mediators that activate neurovascular unit (NVU). When the tight junctions are broken and the basement membrane is disrupted by matrix metalloproteinases produced by active endothelial and pericellular cells ...
Yu Yang +4 more
wiley +1 more source
Investigating the role of SARM1 in central nervous system
Ibrain, EarlyView.Sterile‐α and Toll/interleukin 1 receptor (TIR) motif‐containing protein 1 (SARM1) is a pivotal molecule that has garnered extensive attention in neuroscience. As an intracellular molecule, SARM1 possesses various crucial biological functions in the nervous system.
Junjie Wang +4 more
wiley +1 more source
The structural and functional integrity of peripheral nerves depends on the glial-derived signal desert hedgehog [PDF]
, 2006 We show that desert hedgehog ( dhh), a signaling molecule expressed by Schwann cells, is essential for the structural and functional integrity of the peripheral nerve.
Jessen, KR +6 more
core
Ibrain, Volume 11, Issue 1, Page 3-18, Spring 2025.With the advantages of high‐resolution imaging, efficient image acquisition, intraoperative real‐time detection, and radiation‐free and noninvasive characteristics, optical coherence tomography (OCT) provides accurate diagnosis and effective intraoperative guidance for the minimally invasive diagnosis and treatment of central nervous system (CNS ...
Jiuhong Li +10 more
wiley +1 more source
FURTHER OBSERVATIONS ON THE STRUCTURE OF MYELIN SHEATHS IN THE CENTRAL NERVOUS SYSTEM [PDF]
, 1964 Alan Peters
openalex +1 more source
Ibrain, EarlyView.Polysaccharide‐based nanoparticles offer versatile platforms for drug delivery and immune modulation in neurodegenerative diseases. This review highlights their potential in treating Alzheimer's, Parkinson's, and multiple sclerosis, focusing on targeted delivery and neuroinflammation.
Leto‐Aikaterini Tziveleka +5 more
wiley +1 more source
Siriraj Medical Journal, 2009 Objective: The study is to observe the histological structure and the ultrastructure of the peripheral nerve from cadaveric embalmed specimens and from fresh specimens by light microscope and by transmission electron microscope.
Kunnika Chatyingmongkol +2 more
doaj
The signal synchronization function of myelin [PDF]
arXivThe myelinated axons are widely present in both central and peripheral nervous systems. Its unique compact spiraling structure poses significant challenges to understanding its biological functions and developmental mechanisms. Conventionally, myelin is considered as an insulating layer to achieve saltatory conduction for the enhancement of the neural ...
arxiv