Results 151 to 160 of about 201,896 (346)

The Multiple Roles of Myelin Protein Genes During the Development of the Oligodendrocyte

ASN Neuro, 2009
It has become clear that the products of several of the earliest identified myelin protein genes perform functions that extend beyond the myelin sheath. Interestingly, these myelin proteins, which comprise proteolipid protein, 2′, 3′-cyclic nucleotide 3′-
Daniel Fulton, Pablo M Paez, Anthony T Campagnoni   +2 more
doaj   +1 more source

Specific Iron Binding to Natural Sphingomyelin Membrane Induced by Non-Specific Co-Solutes [PDF]

Hypothesis: Sphingomyelin (SPM), a crucial phospholipid in the myelin sheath, is vital in insulating nerve fibers. We hypothesize that iron ions selectively bind to the phosphatidylcholine (PC) template within the SPM membrane under near-physiological conditions, disrupting membrane organization.
arxiv   +1 more source

Myelin sheath survival after guanethidine-induced axonal degeneration. [PDF]

, 1992
Grahame J. Kidd, John W. Heath, Bruce D. Trapp, Peter R. Dunkley   +3 more
openalex   +1 more source

Proteomic Insight Into Alzheimer's Disease Pathogenesis Pathways

PROTEOMICS, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a leading cause of dementia, but the pathogenesis mechanism is still elusive. Advances in proteomics have uncovered key molecular mechanisms underlying AD, revealing a complex network of dysregulated pathways, including amyloid metabolism, tau pathology, apolipoprotein E (APOE), protein degradation ...
Taekyung Ryu, Kyungdo Kim, Nicholas Asiimwe, Chan Hyun Na   +3 more
wiley   +1 more source

Axon and Myelin Sheath Segmentation in Electron Microscopy Images using Meta Learning. [PDF]

IEEE Appl Imag Pattern Recognit Workshop, 2022
Nguyen NP, Lopez S, Smith CL, Lever TE, Nichols NL, Bunyak F.   +5 more
europepmc   +1 more source

Myelin dysfunction/degradation in the central nervous system: why are myelin sheaths susceptible to damage? [PDF]

, 1999
Monika Bradl
openalex   +1 more source

Inner Ear Immunity and Audio‐Vestibular Dysfunction

Sensory Neuroscience, EarlyView.
Diagram of the immune response of the inner ear and associated damage. ABSTRACT The inner ear is a critical sensory organ regulated by the immune system to maintain balance and respond to external stimuli. Immune cells like macrophages, lymphocytes, neutrophils, and natural killer cells play important roles in inner ear immunity. Inflammatory mediators,
Xiaofei Li, Hanyue Wang, Jing Wang, Maoli Duan, Yafeng Lyu   +4 more
wiley   +1 more source

Bioinformatics analysis of myelin-microbe interactions suggests multiple types of molecular mimicry in the pathogenesis of multiple sclerosis.

PLoS ONE
Multiple sclerosis (MS) is a devastating autoimmune disease that leads to the destruction of the myelin sheath in the human central nervous system (CNS).
Ali Bigdeli, Mostafa Ghaderi-Zefrehei, Bluma J Lesch, Mehrdad Behmanesh, S Shahriar Arab   +4 more
doaj   +1 more source

Regeneration of sensory nerve branches in extraction socket and surrounding alveolar bone in rat: immunohistochemical observation of the axon and myelin sheath changes. [PDF]

Odontology, 2023
Kakuta W, Matsunaga S, Otsu Y, Kitamura K, Abe S, Yajima Y, Sekine H.   +6 more
europepmc   +1 more source

Functional Gap Junctions in the Schwann Cell Myelin Sheath [PDF]

, 1998
Rita J. Balice‐Gordon, Linda Jo Bone, Steven S. Scherer   +2 more
openalex   +1 more source