Results 151 to 160 of about 48,712 (325)

Cdc42 and Rac1 Signaling Are Both Required for and Act Synergistically in the Correct Formation of Myelin Sheaths in the CNS [PDF]

, 2006
Tina Buerki‐Thurnherr, Yves Benninger, Xunwei Wu, Anna Chrostek, Sven Krause, Klaus‐Armin Nave, Robin J.M. Franklin, Cord Brakebusch, Ueli Suter, João B. Relvas   +9 more
openalex   +1 more source

Myelin Sheath Regeneration [PDF]

, 2020

openalex   +1 more source

Oligodendrocyte Precursor Cells in Demyelination Repair: Mechanisms, Crosstalk, and Therapeutic Frontiers

Medicine Bulletin, EarlyView.
ABSTRACT In multiple sclerosis (MS), demyelination is often accompanied by severe motor and cognitive disability. Remyelination is the process of regenerating new myelin sheath on impaired axons, which is typically carried out by oligodendrocyte precursor cells (OPCs).
Zixin Gao, Mengdi Guo, Kehan Chen, Mei‐Ling Jiang, Lin‐ming Zhang, Lorenzo Di Cesare Mannelli, Cun‐jin Zhang   +6 more
wiley   +1 more source

Axon and Myelin Sheath Segmentation in Electron Microscopy Images using Meta Learning. [PDF]

IEEE Appl Imag Pattern Recognit Workshop, 2022
Nguyen NP, Lopez S, Smith CL, Lever TE, Nichols NL, Bunyak F.   +5 more
europepmc   +1 more source

\u3cem\u3eEx Vivo\u3c/em\u3e Diffusion Tensor Imaging of Spinal Cord Injury in Rats of Varying Degrees of Severity [PDF]

, 2013
The aim of this study was to characterize magnetic resonance diffusion tensor imaging (DTI) in proximal regions of the spinal cord following a thoracic spinal cord injury (SCI). Sprague–Dawley rats (n = 40) were administered a control, mild, moderate, or
Jirjis, Michael, Kurpad, Shekar N., Schmit, Brian D.   +2 more
core   +1 more source

6 4 Integrin and Dystroglycan Cooperate to Stabilize the Myelin Sheath [PDF]

, 2008
Alessandro Nodari, Stefano C. Previtali, Gabriele Dati, Simona Occhi, Felipe A. Court, Cristina Colombelli, Desirée Zambroni, Giorgia Dina, Ubaldo Del Carro, Kevin P. Campbell, Angelo Quattrini, Lawrence Wrabetz, M. Laura Feltri   +12 more
openalex   +1 more source

Dysregulation of Monounsaturated Fatty Acids is Related to α‐Synuclein in Multiple System Atrophy

Movement Disorders, EarlyView.
Abstract Background Multiple system atrophy (MSA) is a neurodegenerative disease pathologically characterized by the presence of glial cytoplasmic inclusions (GCI) composed of α‐synuclein aggregates. In Parkinson's disease, increases in monounsaturated fatty acids (MUFA) in phospholipid membranes promote α‐synuclein binding, aggregation, and toxicity ...
Finula I. Isik, YuHong Fu, Russell Pickford, Qi Cheng, Yue Yang, Simon J.G. Lewis, Nicolas Dzamko, Glenda M. Halliday, Woojin Scott Kim   +8 more
wiley   +1 more source

Novel insights into brain lipid metabolism in Alzheimer's disease: Oligodendrocytes and white matter abnormalities

FEBS Open Bio
Alzheimer's disease (AD) is the most common cause of dementia. A genome‐wide association study has shown that several AD risk genes are involved in lipid metabolism.
Noe Kawade, Koji Yamanaka
doaj   +1 more source

Oligodendrocyte HCN2 Channels Regulate Myelin Sheath Length. [PDF]

J Neurosci, 2021
Swire M, Assinck P, McNaughton PA, Lyons DA, Ffrench-Constant C, Livesey MR.   +5 more
europepmc   +1 more source

Expression, purification, and initial characterization of different domains of recombinant mouse 2',3'-cyclic nucleotide 3'-phosphodiesterase, an enigmatic enzyme from the myelin sheath [PDF]

, 2010
Matti Myllykoski, Petri Kursula
openalex   +1 more source