Results 171 to 180 of about 201,896 (346)

Novel insights into brain lipid metabolism in Alzheimer's disease: Oligodendrocytes and white matter abnormalities

open access: yesFEBS Open Bio
Alzheimer's disease (AD) is the most common cause of dementia. A genome‐wide association study has shown that several AD risk genes are involved in lipid metabolism.
Noe Kawade, Koji Yamanaka
doaj   +1 more source

Intermittent Fasting Enhances Motor Coordination Through Myelin Preservation in Aged Mice

open access: yesAging Cell, EarlyView.
Over a 10‐week regimen, IMF significantly improved locomotor activity, motor coordination, and muscle strength compared to controls (p < 0.01). Resting‐state fMRI (rsfMRI) demonstrated that IMF modulates brain‐wide functional connectivity, enhancing communication between key brain regions.
Zhuang Liu   +12 more
wiley   +1 more source

Incorporating familial risk, lifestyle factors, and pharmacogenomic insights into personalized noncommunicable disease (NCD) reports for healthcare funder beneficiaries participating in the Open Genome Project

open access: yesAnnals of Human Genetics, EarlyView.
Abstract Introduction An ethics‐guided decision‐making framework was developed for applying pathology‐supported genetic testing, a multifaceted pharmacodiagnostic approach that translates population risk stratification into clinical utility. We introduce this service, supported by the Open Genome Project, which aligns with the beneficence principle in ...
Manie De Klerk   +6 more
wiley   +1 more source

Evaluation of neurotoxic effects of lead acetat on rat radial nerve

open access: yesمجله دانشگاه علوم پزشکی گرگان, 2005
Background&Objective: Lead toxicity is a common popular problem. Many researches were performed about this toxicity both in-vivo and in-vitro since 100 years ago.Those studies showed that lead have toxic effects such as behavioral disorders, decrease of ...
M.Mehdizadeh (PhD)   +3 more
doaj  

Lipid-Protein and Lipid-Lipid Interactions in the Myelin Sheath [PDF]

open access: bronze, 2011
Hande Ozgen   +2 more
openalex   +1 more source

TIMP-1 associates with myelin membrane and preserves myelin in injured peripheral nerve

open access: yesNeurobiology of Disease
Myelin enables rapid impulse propagation in axons across long distances. Following peripheral nerve injury, Schwann cells provide trophic, metabolic, and immune support to damaged neurons.
Hanbum Joe   +8 more
doaj  

A narrative literature review about alpha‐lipoic acid role in dry eye and ocular surface disease

open access: yesActa Ophthalmologica, EarlyView.
Abstract Ocular surface diseases (OSD) include various conditions that affect the eye's surface, causing discomfort and pain. One such condition, dry eye disease (DED), is a multifactorial disorder that significantly impacts patients' quality of life, with prevalence rates ranging from 5% to 50% and higher incidence in women.
Antonio J. Mateo Orobia   +4 more
wiley   +1 more source

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