Alzheimer's disease (AD) is the most common cause of dementia. A genome‐wide association study has shown that several AD risk genes are involved in lipid metabolism.
Noe Kawade, Koji Yamanaka
doaj +1 more source
Expression, purification, and initial characterization of different domains of recombinant mouse 2',3'-cyclic nucleotide 3'-phosphodiesterase, an enigmatic enzyme from the myelin sheath [PDF]
Matti Myllykoski, Petri Kursula
openalex +1 more source
Intermittent Fasting Enhances Motor Coordination Through Myelin Preservation in Aged Mice
Over a 10‐week regimen, IMF significantly improved locomotor activity, motor coordination, and muscle strength compared to controls (p < 0.01). Resting‐state fMRI (rsfMRI) demonstrated that IMF modulates brain‐wide functional connectivity, enhancing communication between key brain regions.
Zhuang Liu+12 more
wiley +1 more source
Knockdown of G protein-coupled receptor-17 (GPR17) facilitates the regeneration and repair of myelin sheath post-periventricular leukomalacia (PVL). [PDF]
He L+6 more
europepmc +1 more source
Abstract Introduction An ethics‐guided decision‐making framework was developed for applying pathology‐supported genetic testing, a multifaceted pharmacodiagnostic approach that translates population risk stratification into clinical utility. We introduce this service, supported by the Open Genome Project, which aligns with the beneficence principle in ...
Manie De Klerk+6 more
wiley +1 more source
Evaluation of neurotoxic effects of lead acetat on rat radial nerve
Background&Objective: Lead toxicity is a common popular problem. Many researches were performed about this toxicity both in-vivo and in-vitro since 100 years ago.Those studies showed that lead have toxic effects such as behavioral disorders, decrease of ...
M.Mehdizadeh (PhD)+3 more
doaj
Lipid-Protein and Lipid-Lipid Interactions in the Myelin Sheath [PDF]
Hande Ozgen+2 more
openalex +1 more source
TIMP-1 associates with myelin membrane and preserves myelin in injured peripheral nerve
Myelin enables rapid impulse propagation in axons across long distances. Following peripheral nerve injury, Schwann cells provide trophic, metabolic, and immune support to damaged neurons.
Hanbum Joe+8 more
doaj
A narrative literature review about alpha‐lipoic acid role in dry eye and ocular surface disease
Abstract Ocular surface diseases (OSD) include various conditions that affect the eye's surface, causing discomfort and pain. One such condition, dry eye disease (DED), is a multifactorial disorder that significantly impacts patients' quality of life, with prevalence rates ranging from 5% to 50% and higher incidence in women.
Antonio J. Mateo Orobia+4 more
wiley +1 more source