Results 21 to 30 of about 48,603 (346)
Microglia phagocytose myelin sheaths to modify developmental myelination [PDF]
Nature Neuroscience, 2020 During development, oligodendrocytes contact and wrap neuronal axons with myelin. Similarly to neurons and synapses, excess myelin sheaths are produced and selectively eliminated, but how elimination occurs is unknown. Microglia, the resident immune cells of the central nervous system, engulf surplus neurons and synapses. To determine whether microglia
Alexandria N. Hughes, Bruce Appel
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A RADIAL COMPONENT OF CENTRAL MYELIN SHEATHS [PDF]
The Journal of Cell Biology, 1961 Alan Peters
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Advanced Maternal Age Impairs Myelination in Offspring Rats
Frontiers in Pediatrics, 2022 The effects of advanced maternal age (AMA) on the neurodevelopment of offspring are becoming increasingly important. Myelination is an important aspect of brain development; however, a limited number of studies have focused on the effects of AMA on ...
Wei Han +4 more
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Spatio-temporal modeling of saltatory conduction in neurons using Poisson-Nernst-Planck treatment and estimation of conduction velocity [PDF]
Brain Multiphysics, 2022, 2022 Action potential propagation along the axons and across the dendrites is the foundation of the electrical activity observed in the brain and the rest of the central nervous system. Theoretical and numerical modeling of this action potential activity has long been a key focus area of electro-chemical neuronal modeling.
arxiv +1 more source
Title: Effect of six-week high intensity interval training under simulated microgravity condition on morphology of radial nerve myelin sheet in male rats [PDF]
فصلنامه علوم و فناوری فضایی, 2019 The purpose of this study was to investigate the effect of six weeks of HIIT under simulated microgravity condition on morphological changes of radial nerve myelin sheath in male rats.
hossein ghadampour-vahed +3 more
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Microtubules, Myelin Sheaths, and Altered Behavior [PDF]
eneuro, 2021 Mice are skttish creatures that innately hide from perceived threats by staying out of open areas, freezing to avoid predators, or hiding in dark spaces when an adverse stimulus is sensed. However, after inducing a global TPPP (tubulin polymerization promoting protein) gene knock-out (KO), which results in reduced myelin length and thickness (Fu et al.,
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Mechanical Responses of a Single Myelin Layer: A Molecular Simulation Study
Biomolecules, 2023 The myelin sheath provides insulation to the brain’s neuron cells, which aids in signal transmission and communication with the body. Degenerated myelin hampers the connection between the glial cells, which are the front row responders during traumatic ...
Fairuz Maliha, Ashfaq Adnan
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Epilepsia Open, EarlyView., 2022 Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force initiated the TASK3 working group to create common data elements (CDEs) for various aspects of preclinical epilepsy research studies, which could help improve the standardization of experimental designs.
Eleonora Aronica +6 more
wiley +1 more source
Peripheral Nerve Diffusion Tensor Imaging: Assessment of Axon and Myelin Sheath Integrity. [PDF]
PLoS ONE, 2015 To investigate the potential of diffusion tensor imaging (DTI) parameters as in-vivo biomarkers of axon and myelin sheath integrity of the median nerve in the carpal tunnel as validated by correlation with electrophysiology.MRI examinations at 3T ...
A Heckel +7 more
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A myelin sheath protein forming its lattice. [PDF]
J Biol Chem, 2020 The formation of a mature, multilayered myelin sheath requires the compaction of lipid bilayers, but the molecular mechanism by which these bilayers condense is an open question. In this issue, Ruskamo et al. find that peripheral myelin protein P2 forms an ordered three-dimensional lattice within model membranes using Escherichia coli polar lipid ...
Tsuge H.
europepmc +5 more sources