Axon and Myelin Sheath Segmentation in Electron Microscopy Images using Meta Learning. [PDF]
IEEE Appl Imag Pattern Recognit Workshop, 2022 Nguyen NP +5 more
europepmc +3 more sources
Myelin Sheath Decompaction, Axon Swelling, and Functional Loss during Chronic Secondary Degeneration in Rat Optic Nerve [PDF]
Investigative Ophthalmology and Visual Science, 2012 Sophie C. Payne +4 more
openalex +2 more sources
The RNA binding protein fragile X mental retardation protein promotes myelin sheath growth. [PDF]
Glia, 2020 During development, oligodendrocytes in the central nervous system extend a multitude of processes that wrap axons with myelin. The highly polarized oligodendrocytes generate myelin sheaths on many different axons, which are far removed from the cell ...
Doll CA, Yergert KM, Appel BH.
europepmc +2 more sources
Oligodendrocytes express synaptic proteins that modulate myelin sheath formation. [PDF]
Nat Commun, 2019 Vesicular release from neurons promotes myelin sheath growth on axons. Oligodendrocytes express proteins that allow dendrites to respond to vesicular release at synapses, suggesting that axon-myelin contacts use similar communication mechanisms as ...
Hughes AN, Appel B.
europepmc +2 more sources
Myelin sheath structure and regeneration in peripheral nerve injury repair. [PDF]
Proc Natl Acad Sci U S A, 2019 Significance Afferent and efferent nerve fibers cannot be distinguished based on the axonal diameter or the presence of the Remark bundle. The compaction of the myelin sheath involves 2 steps: 1) The distance between the 2 layers of cell membranes in the
Liu B +15 more
europepmc +2 more sources
SKAP2 as a new regulator of oligodendroglial migration and myelin sheath formation
bioRxiv, 2021 Oligodendroglial progenitor cells (OPC) are highly proliferative and migratory bipolar cells, which differentiate into complex myelin forming and axon ensheathing mature oligodendrocytes during myelination.
Julia Ghelman +5 more
semanticscholar +1 more source
Ca <sup>2+</sup> activity signatures of myelin sheath formation and growth in vivo. [PDF]
Nat Neurosci, 2018 During myelination, individual oligodendrocytes initially over-produce short myelin sheaths, which are either retracted or stabilized. By live-imaging oligodendrocyte Ca2+ activity in vivo, we find that high-amplitude, long-duration Ca2+ transients in ...
Baraban M, Koudelka S, Lyons DA.
europepmc +3 more sources
Aerobic exercise attenuates abnormal myelination and oligodendrocyte differentiation in 3xTg-AD mice
Experimental Gerontology, 2023 Pathological features of Alzheimer's Disease (AD) include alterations in the structure and function of neurons as well as of myelin sheaths. Accumulated evidence shows that aerobic type of exercise can enhance neuroplasticity in mouse models of AD ...
Dan Qiu +4 more
doaj +1 more source