Results 71 to 80 of about 43,839 (265)
Neurotherapeutics, 2021 Myelin is a key evolutionary specialization and adaptation of vertebrates formed by the plasma membrane of glial cells, which insulate axons in the nervous system. Myelination not only allows rapid and efficient transmission of electric impulses in the axon by decreasing capacitance and increasing resistance but also influences axonal metabolism and ...
openaire +3 more sources
Advanced Science, EarlyView.By investigating auditory hyperexcitability in a mouse model for hereditary deafness, this study identified a subpopulation of afferent neurons of the auditory nerve marked by Otogl expression. Despite their apparently normal hearing, Otogl+/− mice display poor activation of afferent neurons processing loud sounds and an elevation of the middle the ear
Mathilde Gagliardini +24 more
wiley +1 more source
Human Brain Mapping, Volume 44, Issue 1, Page 218-228, January 2023., 2023 The use of magnetoencephalography and the Human Connectome Project multimodal parcellation revealed precise cortical areas underlying attention modulation of auditory sensory activity in healthy individuals and impairments in early psychosis. The sensory reduction and attention modulation impairment indicate pathophysiology proximal to disease onset ...
Mark T. Curtis +3 more
wiley +1 more source
Developmental hypomyelination in Wolfram syndrome: New insights from neuroimaging and gene expression analyses [PDF]
, 2019 Wolfram syndrome is a rare multisystem disorder caused by mutations in WFS1 or CISD2 genes leading to brain structural abnormalities and neurological symptoms. These abnormalities appear in early stages of the disease.
Dougherty, Joseph +7 more
core +1 more source
What's the Function of Connexin 32 in the Peripheral Nervous System? [PDF]
, 2018 Connexin 32 (Cx32) is a fundamental protein in the peripheral nervous system (PNS) as its mutations cause the X-linked form of Charcot-Marie-Tooth disease (CMT1X), the second most common form of hereditary motor and sensory neuropathy and a demyelinating
Bortolozzi, Mario
core +1 more source
Progress and Perspectives in 2D Piezoelectric Materials for Piezotronics and Piezo‐Phototronics
Advanced Science, EarlyView.This review examines advancements in 2D materials, focusing on their applications in piezotronics and piezo‐phototronics. It discusses key materials like TMDs, h‐BN, and phosphorene, highlighting their unique mechanical, electronic, and optical properties.
Fengyi Pang +6 more
wiley +1 more source
Human Mutation, Volume 43, Issue 12, Page 1866-1871, December 2022., 2022 Abstract Galloway–Mowat syndrome (GAMOS) is a very rare condition characterized by early‐onset nephrotic syndrome and microcephaly with variable neurologic features. While considerable genetic heterogeneity of GAMOS has been identified, the majority of cases are caused by pathogenic variants in genes encoding the four components of the Kinase ...
Ernestine Treimer +8 more
wiley +1 more source
A physical perspective to understand myelin. II. The physical origin of myelin development [PDF]
arXiv, 2021 The physical principle of myelin development is obtained from our previous study by explaining Peter's quadrant mystery: an external applied negative and positive E-field can promote and inhibit the growth of the inner tongue of the myelin sheath, respectively. In this study, this principle is considered as a fundamental hypothesis, named Hypothesis-E,
arxiv
Combination Therapy With Fingolimod and Neural Stem Cells Promotes Functional Myelination [PDF]
, 2019 Myelination, which occurs predominantly postnatally and continues throughout life, is important for proper neurologic function of the mammalian central nervous system (CNS).
Ciric, Bogoljub +7 more
core +1 more source
Adult mesenchymal stem cell therapy for myelin repair in Multiple Sclerosis. [PDF]
, 2012 Multiple sclerosis (MS) is a demyelinating immune-mediated disease of the central nervous system (CNS). It is the most frequent neurological disease in young adults and affects over 2 million people worldwide.
Aigner, Ludwig, Rivera, Francisco J
core +2 more sources