Results 221 to 230 of about 396,076 (261)
Selective SIK2/SIK3 inhibition reprograms pro- and antiinflammatory pathways in myeloid cells, improving autoimmune disease outcomes. [PDF]
JCI InsightDe Vos S +20 more
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Single-cell and spatial transcriptomics reveal transplant-associated T cells and myeloid cells in human liver transplantation. [PDF]
Front ImmunolZhou T +10 more
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Myeloid-derived suppressor cells in the era of increasing myeloid cell diversity [PDF]
Nature Reviews Immunology, 2021 Myeloid-derived suppressor cells (MDSCs) are pathologically activated neutrophils and monocytes with potent immunosuppressive activity. They are implicated in the regulation of immune responses in many pathological conditions and are closely associated with poor clinical outcomes in cancer.
Filippo Veglia +2 more
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The International Journal of Biochemistry & Cell Biology, 2004
Granulocytes and monocytes, collectively called myeloid cells, are differentiated descendants from common progenitors derived from hematopoietic stem cells in the bone marrow. Commitment to either lineage of myeloid cells is controlled by distinct transcription factors followed by terminal differentiation in response to specific colony-stimulating ...
Hiroshi, Kawamoto, Nagahiro, Minato
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Granulocytes and monocytes, collectively called myeloid cells, are differentiated descendants from common progenitors derived from hematopoietic stem cells in the bone marrow. Commitment to either lineage of myeloid cells is controlled by distinct transcription factors followed by terminal differentiation in response to specific colony-stimulating ...
Hiroshi, Kawamoto, Nagahiro, Minato
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Journal of Leukocyte Biology, 1999
Abstract There is considerable but as yet incomplete evidence for two developmental lineages of dendritic cells: a myeloid lineage shared with phagocytes and a lymphoid lineage shared with T cells. The two corresponding functional states, which may not require the existence of two formal lineages, are that myeloid dendritic cells capture
R M, Steinman, K, Inaba
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Abstract There is considerable but as yet incomplete evidence for two developmental lineages of dendritic cells: a myeloid lineage shared with phagocytes and a lymphoid lineage shared with T cells. The two corresponding functional states, which may not require the existence of two formal lineages, are that myeloid dendritic cells capture
R M, Steinman, K, Inaba
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The Myeloid Cell Compartment—Cell by Cell
Annual Review of Immunology, 2019Myeloid cells are a major cellular compartment of the immune system comprising monocytes, dendritic cells, tissue macrophages, and granulocytes. Models of cellular ontogeny, activation, differentiation, and tissue-specific functions of myeloid cells have been revisited during the last years with surprising results; for example, most tissue macrophages ...
Baßler, Kevin +4 more
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CD1c(+) myeloid dendritic cells in myeloid neoplasia
Cytometry Part B: Clinical Cytometry, 2015We determined the normal level and phenotype of CD1c(+) myeloid dendritic cells (MDCs) in blood and bone marrow and evaluated the level of CD1c(+) MDCs in 295 myeloid neoplasms. CD1c(+) MDCs were increased above the mean level of non‐neoplastic hospital controls in 18.0% (53/295) of myeloid malignancies, increased three standard deviations above the ...
Howard J, Meyerson +7 more
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Heterogeneity and origins of myeloid cells
Current Opinion in Hematology, 2022Purpose of review Myeloid cells – granulocytes, monocytes, macrophages and dendritic cells (DCs) – are innate immune cells that play key roles in pathogen defense and inflammation, as well as in tissue homeostasis and repair.
Yáñez Boyer, Alberto +2 more
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Science, 2017
Innate Immunity Hematopoietic stem cells are a common progenitor of adaptive and innate immune cells. However, the precise factors that guide differentiation down these disparate pathways remain unclear, in part owing to difficulties in working with small numbers of precursor cells. Lee et al .
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Innate Immunity Hematopoietic stem cells are a common progenitor of adaptive and innate immune cells. However, the precise factors that guide differentiation down these disparate pathways remain unclear, in part owing to difficulties in working with small numbers of precursor cells. Lee et al .
openaire +2 more sources