Results 241 to 246 of about 126,969 (246)

Stimulatory and Inhibitory Differentiation of Human Myeloid Dendritic Cells

Clinical Immunology, 2000
Dendritic cells (DCs) play a critical obligate role in presenting antigens to T cells for activation. In the process, upon antigen capture, DCs undergo maturation and become more stimulatory. Human myeloid DCs can be generated from various sources, including blood, bone marrow, and CD34(+) stem cells.
A, Chakraborty, L, Li, N G, Chakraborty, B, Mukherji   +3 more
openaire   +2 more sources

[Dendritic cells and acute myeloid leukemia].

Zhongguo shi yan xue ye xue za zhi, 2014
Dendritic cells can be derived from leukemia cells and normal precursor cells in the patients with acute myeloid leukemia (AML). Dendritic cells may capture leukemia antigen in bone marrow or lymph nodes, and present leukemia common antigen to stimulate proliferation of specific CD8(+) T cells, playing anti-leukemia effect. Dendritic cells for clinical
Zhan-Qiang, Zhang, Bin, Zhang, Hu, Chen
openaire   +1 more source

Dendritic cell potentials of early lymphoid and myeloid progenitors

Blood, 2001
It has been proposed that there are at least 2 classes of dendritic cells (DCs), CD8α+ DCs derived from the lymphoid lineage and CD8α− DCs derived from the myeloid lineage. Here, the abilities of lymphoid- and myeloid-restricted progenitors to generate DCs are compared, and their overall contributions to the DC compartment are evaluated.
M G, Manz, D, Traver, T, Miyamoto, I L, Weissman, K, Akashi   +4 more
openaire   +2 more sources

The function of myeloid dendritic cells in rheumatoid arthritis

Rheumatology International, 2017
Rheumatoid arthritis (RA) is a systemic autoimmune disease that causes joint pain, inflammation, and loss of function. Disease pathogenesis involves activation and proliferation of autoreactive pro-inflammatory effector T cells. While the details of RA onset and progression remain controversial, dendritic cell (DC) numbers dramatically increase in the ...
Mary Beth, Yu, William H R, Langridge
openaire   +2 more sources

Derivation of Dendritic Cells from Myeloid and Lymphoid Precursors

International Reviews of Immunology, 2001
The antigen presenting dendritic cells (DC) found in mouse and human lymphoid tissues are heterogeneous. Several subsets of mature DC have been described and these may correspond to distinct lineages. In this review, we present evidence obtained from a series of studies on the lineage origin of DC.
L, Wu, S, Vandenabeele, K, Georgopoulos
openaire   +2 more sources

Early plasmacytoid dendritic cell leukemia/lymphoma coexpressing myeloid antigenes

Annals of Hematology, 2004
Early plasmacytoid dendritic cell (pDC) leukemia/lymphoma has recently been described as a CD4(+)CD56(+) lineage negative malignancy with characteristic clinical, morphologic, immunophenotypic, and biological features. We present a case of a 72-year-old man who was diagnosed with isolated skin involvement 30 months ago and received numerous ...
A A N, Giagounidis, M, Heinsch, S, Haase, C, Aul   +3 more
openaire   +2 more sources