Results 231 to 240 of about 160,066 (290)

Therapeutic advances in acute myeloid leukemia: from LSD1 blockade to PROTAC-based strategies. [PDF]

Ann Med Surg (Lond)
Khan SA, Qamar MA, Feroze MT.
europepmc   +1 more source

Epigenetic Regulation in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
The aim of this narrative literature review was to identify epigenetic marks associated with periodontitis and to place them in a biological context. The literature was reviewed based on pre‐defined criteria. Cell type specific chromatin and mRNA modifications were included.
Henrik Dommisch, Arne Sönke Schäfer, Denica Kuzmanova, Dominique S. Michaud   +3 more
wiley   +1 more source

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

Mechanisms and functions of chemerin in cancer: Potential roles in therapeutic intervention [PDF]

, 2018
Pachynski, Russell K, Shin, Woo Jae, Zabel, Brian A   +2 more
core   +1 more source

The Keystone‐Pathogen Hypothesis Updated: The Role of Porphyromonas gingivalis in Periodontitis

Journal of Periodontal Research, EarlyView.
Porphyromonas gingivalis orchestrates a coordinated manipulation of immune and inflammatory responses in periodontal tissues which leads to the generation of a dysbiotic, subgingival biofilm community, and progression of periodontitis. The type 9 secretion system, lipid A modification, and the formation of outer membrane vesicles are important ...
Mike A. Curtis, James A. Garnett, Richard P. Darveau   +2 more
wiley   +1 more source

The oncogenic role of ecotropic viral integration site 1 in hematological malignancies: mechanisms of activation and leukemogenesis. [PDF]

Front Immunol
Hao Y, Liu J, Lou J, Yan J.
europepmc   +1 more source

In Silico Perturbation Identifies Transcription Factors as Protective Targets in HSPCs After Irradiation. [PDF]

Int J Mol Sci
Tao Z, Zhang Q, Chen Y, Lv S, Huang Q, Tian H, Liu Q, Li C, Wang Y, Lu H, Quan C, Chen H, Lu Y, Zhou G.   +13 more
europepmc   +1 more source

Metabolic and epigenetic interplay in HSPC specification: A balance between extrinsic and intrinsic cues. [PDF]

iScience
Kalogeraki M, Rondeau V, Abou Nader Z, Espéli M, Balabanian K.   +4 more
europepmc   +1 more source

Bidirectional Interactions Between Immune Regulation and the Insulin-like Growth Factor Axis in Colorectal Cancer. [PDF]

Int J Mol Sci
Centeno-Girona H, López-Acevedo SN, Zenón-Meléndez C, Díaz-Miranda OL, Caraballo EV.   +4 more
europepmc   +1 more source

Type I interferons in bacterial diseases: myeloid cells at the crossroads of protection and pathology. [PDF]

Front Immunol
Lyadova I.
europepmc   +1 more source