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Targetoid ulcerating eruption in a previously healthy man. [PDF]

JAAD Case Rep
Giordano JA, Cohen OG, Flowers RH, Moore ME.   +3 more
europepmc   +1 more source

Myeloid Differentiation Factor 88 (MyD88)-Deficiency Increases Risk of Diabetes in Mice

Myeloid Differentiation Factor 88 (MyD88)-Deficiency Increases Risk of Diabetes in Mice
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Myeloid differentiation factor 88 expression in eyelid specimens of rosacea

Orbit, 2021
Rosacea is a common cause of ocular surface disease. Specific immunologic features have been implicated in its pathogenesis, including toll-like receptors, mitogen-associated kinase, and nuclear factor kappa-B. Myeolid differentiation factor 88 (MYD88) has been associated with these elements, suggesting a role for this protein in rosacea.
Edward J, Wladis, Thilaka, Arunachalam, Juliann E, LaJoie, Kevin W, Lau, Alejandro P, Adam   +4 more
openaire   +2 more sources

Evolutionary and functional conservation of myeloid differentiation factor 88 (MyD88) in amphibian Xenopus tropicalis

Gene, 2023
As a universal adaptor used by most TLR members, the myeloid differentiation factor 88 (MyD88) plays essential roles in TLR-mediated inflammatory response of invertebrate and vertebrate animals, and functional features of MyD88 remain largely unknown in amphibians. In this study, a MyD88 gene named Xt-MyD88 was characterized in the Western clawed frog (
Hongli Xia, Yishan Lu, Zhen Gan
exaly   +3 more sources

Identification and Functional Analysis of Myeloid Differentiation Factor 88 (Myd88) in Early Development of Haliotis Diversicolor

Fish & Shellfish Immunology, 2023
Myeloid differentiation factor 88 (MyD88) is a universal adaptor protein and plays an important role in the signal transduction of Toll like receptors (TLR) family. In this study, the MyD88 gene from the Haliotis diversicolor (hdMyD88) was identified.
Xiaoting Gong, Min Li, Lili Zhang, Shiyu Huang, Guodong Wang   +4 more
openaire   +2 more sources

Myeloid Differentiation Factor 88 Promotes Cisplatin Chemoresistance in Ovarian Cancer

Cell Biochemistry and Biophysics, 2014
To investigate regulatory effects and associated mechanisms of myeloid differentiation factor 88 (MyD88) on cisplatin chemoresistance in human ovarian cancer (OC) cells. The expression of MyD88 in SKOV3/DDP cells was restrained by short interfering RNA (siRNA) of MyD88.
Guanghong, Liu, Peijie, Du, Zhanxin, Zhang   +2 more
openaire   +2 more sources

Functional characterization of myeloid differentiation factor 88 in Nile tilapia (Oreochromis niloticus)

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 2020
Myeloid differentiation factor 88 (MyD88) is an indispensable component of the toll-like receptor (TLR)- and interleukin 1 receptor-mediated signaling pathways and plays an important role in defensive immune responses. In this study, we cloned MyD88 from the Nile tilapia, Oreochromis niloticus (OnMyD88).
Nguyen Bao, Trung, Po-Tsang, Lee
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Identification, functional characterization and expression pattern of myeloid differentiation factor 88 (MyD88) in Nibea albiflora

Fish & Shellfish Immunology, 2022
Myeloid differentiation factor 88 (MyD88), composed of an N-terminal death domain and a C-terminal Toll/interleukin (IL)-IR homology domain, is a key connector protein in the TLR signal transduction pathway. In this study a novel isoform of MyD88 in Nibea albiflora (named as NaMyD88) was identified and functionally characterized (GenBank accession no ...
Xiuqin, Tang, Meijun, Yang, Jiaxin, Liu, Libing, Zheng, Dongdong, Xu, Changfeng, Chi, Zhenming, Lv, Huihui, Liu   +7 more
openaire   +2 more sources