Results 91 to 100 of about 41,188 (289)
HaematologicaIntroduction: Myeloproliferative neoplasms (MPNs) are a main cause of splanchnic vein thrombosis (SVT), with JAK2V617F as a known risk factor. The impact of co-occurring mutations on thrombosis risk remains unclear.
L. Fagiolo +12 more
doaj
International Journal of Laboratory Hematology, EarlyView.ABSTRACT The recent fifth edition WHO classification and ICC classification systems have moved further toward genetically defined classifications of acute leukemias. Both now recognize myelodysplasia‐related (MR) mutations as defining of MDS‐related AML (AML‐MR).
Timothy J. Kirtek, Olga K. Weinberg
wiley +1 more source
Granulocytic Sarcoma of the Male Breast in Acute Myeloblastic Leukemia with Concurrent Deletion of 5q and Trisomy 8 [PDF]
, 2012 We describe a unique case of Granulocytic Sarcoma (GS) in a male, who presented to us with a painless right breast mass without any prior history of Leukemia.
Islam, Md. Monirul +2 more
core +2 more sources
Digital Pathology in Hematopathology: From Vision to Deployment
International Journal of Laboratory Hematology, EarlyView.ABSTRACT Digital pathology (DP) has evolved alongside other technical advances, transforming our daily lives and diagnostic medicine. It is likely that, as in other areas of life, science, and medicine, the overall level of digitization will continue to rise, along with an increasing number of groups implementing DP.
Ryan C. Shean, Anton V. Rets
wiley +1 more source
Haematologica, 2017 The myeloproliferative neoplasms, including polycythemia vera, essential thrombocythemia and myelofibrosis, are distinguished by their debilitating symptom profiles, life-threatening complications and profound impact on quality of life.
Holly L. Geyer +51 more
doaj +1 more source
Absence of CALR Mutations in Idiopathic Erythrocytosis Patients with Low Serum Erythropoietin Levels [PDF]
, 2018 International ...
Catherwood, Mark A +8 more
core +2 more sources
Clinical Discernment, Bone Marrow, and Molecular Diagnostics Are Equally Important to Solve the Phenotypic Mimicry among Subtypes of Myeloproliferative Neoplasms [PDF]
, 2021 Susann Schulze +6 more
openalex +1 more source
Diagnosing Systemic Mastocytosis: State of the Art
International Journal of Laboratory Hematology, EarlyView.ABSTRACT With the advent of effective multikinase and selective tyrosine kinase inhibitors in systemic mastocytosis, diagnosing this rare disease has been critical to improving patient morbidity and mortality. This state‐of‐the‐art review interprets the international diagnostic criteria, including differences between the WHO 5th edition classification ...
Anton Rets, Tracy I. George
wiley +1 more source
Adding hydroxyurea in combination with ruxolitinib improves clinical responses in hyperproliferative forms of myelofibrosis [PDF]
, 2019 Ruxolitinib, an orally bioavailable and selective inhibitor of Janus kinase 1 (JAK1) and JAK2, significantly reduces splenomegaly and disease-related symptoms in patients with myelofibrosis (MF).
Annunziata, M. +14 more
core +1 more source
Unexplained Elevated Vitamin B12: Consider Macro‐B12
International Journal of Laboratory Hematology, EarlyView.ABSTRACT Introduction Elevated vitamin B12 concentration can be caused by supplementation, liver disease, kidney disease, or myeloid malignancies. Persistent, unexplained elevations of vitamin B12 can raise concern among patients and may lead to invasive diagnostic procedures, including bone marrow biopsy.
Evelien G. E. Hurkmans +3 more
wiley +1 more source