Results 221 to 230 of about 54,075 (312)

High‐Content Immunofluorescence Quantification of Transcription Factors: Application to pSMADs for BMP/TGFβ Signaling Pathways

open access: yesCurrent Protocols, Volume 6, Issue 6, June 2026.
Abstract High‐throughput immunofluorescence (IF) detection has become an essential tool in drug discovery for analyzing multiple markers and providing insights into cellular pathways. While IF techniques have been established for decades, high‐content IF protocols vary among laboratories, highlighting the need for standardized and quantitative ...
Valia Khodr   +2 more
wiley   +1 more source

CD47 Promotes, While Exposure to Apoptotic Cells Destroys the Fusion Program of Differentiating Myoblasts. [PDF]

open access: yesFASEB J
Ali MA   +10 more
europepmc   +1 more source

Harnessing Fatty Acid By‐Products for Diabetes Management: Insights From Nutritional and Biological Research

open access: yeseFood, Volume 7, Issue 3, June 2026.
Bioactive fatty acids from agro‐industrial byproducts are highlighted as a promising avenue for managing diabetes in this review, which aims to develop targeted interventions for optimal utilization and therapeutic benefits. ABSTRACT Diabetes mellitus (DM), influenced by multifaceted factors, creates a complex imbalance within the body. Nutrition plays
Youssef Elouafy   +7 more
wiley   +1 more source

Progress on cell therapy for skeletal muscle disorders. [PDF]

open access: yesAdv Drug Deliv Rev
Azzag K, Perlingeiro RCR.
europepmc   +1 more source

Mutation type‐specific transcriptomic signatures and readthrough therapy rescue in SMC1A‐related developmental and epileptic encephalopathy

open access: yesEpilepsia, Volume 67, Issue 6, Page 3185-3198, June 2026.
Abstract Objective This study was undertaken to investigate the molecular consequences of pathogenic variants in the SMC1A gene—particularly those associated with developmental and epileptic encephalopathy (DEE85)—and to evaluate the therapeutic potential of ataluren in restoring SMC1A function and mitigating disease‐related transcriptomic and genomic ...
Maddalena Di Nardo   +7 more
wiley   +1 more source

Commitment to Myogenic Differentiation Significantly Aggravates the RNA Phenotype in Myotonic Dystrophy Type 1. [PDF]

open access: yesNeuropathol Appl Neurobiol
Ripken L   +6 more
europepmc   +1 more source

From Cell Line to Fillet: A Review of Biological and Engineering Strategies in Cultivated Seafood

open access: yesFood Bioengineering, Volume 5, Issue 2, Page 259-277, June 2026.
Bottlenecks of the cultivated seafood industry are shown, and they prevent efficiency of key production stages. These include limited cell line availability, sustainable and cost‐effective media, adaption to suspension culture, sustainable cost‐effective and edible scaffolds, food regulatory approval and acceptance of genetic modified organisms (GMO ...
Angela Trace   +3 more
wiley   +1 more source

The uncoordinated-5 homologue A is a key receptor in netrin-ligand-mediated fast-twitch myotube formation in male mice. [PDF]

open access: yesPhysiol Rep
Maeno T   +15 more
europepmc   +1 more source

Phosphoproteomics Preliminarily Revealed the Differential Phosphorylation Sites and Their Functional Significance in the Longissimus Dorsi Muscle of Kazakh and Xinjiang Brown Cattle

open access: yesFood Science &Nutrition, Volume 14, Issue 6, June 2026.
The phosphorylated protein profiles of the longissimus dorsi muscle tissues of Xinjiang brown cattle and Kazakh cattle were analyzed. RAB12 was a differentially expressed phosphorylated protein. After knockdown of RAB12, the immunofluorescence intensity of MYHC significantly increased, promoting myoblast differentiation.
Ailifeire Wumaier   +9 more
wiley   +1 more source

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